AP BIO FINAL

Which of the following messenger RNA sequences could code for both of the two amino acid sequences above, simply by a shift in the reading frame?

. . . AGCAGCAGCAGC . . .

The rate of oxygen consumption in germinating pea seeds at 26ºC is

0.05 mL / min

Which of the following best estimates the population size of the sea lions in 2000 based on the data shown in Figure 1?

175,000

The graph in Figure 1 shows the percent saturation of fetal hemoglobin and maternal hemoglobin in humans as a function of the partial pressure of oxygen. Based on the data, which of the following values is closest to the predicted difference in the percent saturation of fetal hemoglobin and maternal hemoglobin at 40mmHg40mmHg?

20

If 2n = 48 for a particular cell, then the chromosome number in each cell after meiosis would be

24

The researcher plans to do a chi-square analysis of the data and calculates the expected number of mice with each combination of phenotypes. Which of the following is the expected number of offspring that will display both trait Q and trait R? Responses

36

Poaching is the illegal hunting or capturing of wild animals. Both male and female African elephants have tusks that are a significant source of ivory used for ornaments and jewelry. Assuming that the size of the tusks is heritable, which of the following is the most likely long-term effect of poachers targeting African elephants with large tusks? Responses

A decrease in average tusk size because elephants with large tusks are less likely to survive to reproduce

Based on the information presented, which of the following genetic changes in an individual without diabetes is most likely to result in a disrupted cellular response to insulin signaling similar to that of an individual with type 2 diabetes?

A deletion in the gene encoding the insulin receptor that removes only the cytoplasmic domain of the protein

Based on the data, which of the following best describes the relationship between light and the degradation of mRNA GmRNA G and mRNA HmRNA H?

A longer exposure to light increases the rate of mRNA GmRNA G degradation but not of mRNA HmRNA H degradation.

Lactase is the enzyme needed to digest lactose, the sugar found in milk. Most mammals produce lactase when they are young but stop once nursing ends. In humans however, many people continue to produce lactase into adulthood and are referred to as lactase-persistent. Which of the following mutations is most likely to cause lactase persistence in humans?

A mutation that increases the binding of transcription factors to the promoter of the lactase gene

Which of the following statements about the rate of CO2 fixation in the two types of plants is supported by the data shown in the figures? Responses

At 21%21% O2�2, plant type 22 has a lower rate of CO2CO2 fixation than plant type 11 does in both types of soil.

[Figure 1. Percent survival of normal melanocytes and cancerous melanocyte (melanoma) lines 11 and 22 after treatment with different concentrations of drug X] Which of the following best describes the data in Figure 1 ?

At a concentration above 10 μM10 �M, drug XX reduces melanoma cell survival.

Based on the data in Figure 1, which of the following best describes the inheritance pattern of Friedreich's ataxia?

Autosomal recessive

Butterflies of the genus Colias live in the Rocky Mountains, where they experience a wide range of temperatures. Different variants of a particular glycolytic enzyme in the flight muscles are optimally active at different temperatures. Within the same population, some individual butterflies fly most effectively at 29°C , while others fly most effectively at 40°C. Still others can be equally active at both temperatures. Which of the following claims is most consistent with the observed butterfly behavior?

Butterflies that express two variants of the enzyme are active over a greater range of temperature.

Which of the following descriptions of cell type I and cell type II are most consistent with the data?

Cell type 1: Animal Cell surrounded by a plasma membrane only Cell type 2: Plant cell surrounded by a plasma membrane and a cell wall.

Based on the data, which structural domain is most likely required for DNA binding?

Domain F

[TABLE 1. INTERACTION AND FUNCTION OF COMBINATIONS OF STRUCTURAL VARIANTS OF PROTEINS II AND II] Which of the following claims is best supported by the data from test 5 in Table 1 ?

Domain F is not required for protein-protein interaction.

Which of the following best predicts the effect of disrupting the proton gradient in BAT?

Electron transport and oxidative phosphorylation will be decoupled, generating more heat but less ATPATP.

Which of the following correctly shows the order in which protein X moves through the cell?

Endoplasmic reticulum→→Golgi apparatus→→lysosomes

The Esp gene encodes a protein that alters the structure of the insulin receptor on osteoblasts and interferes with the binding of insulin to the receptor. A researcher created a group of osteoblasts with an Esp mutation that prevented the production of a functional Esp product (mutant). The researcher then exposed the mutant strain and a normal strain that expresses Esp to glucose and compared the levels of insulin in the blood near the osteoblasts (Figure 2). Question Which of the following claims is most consistent with the data shown in Figure 2 ?

Esp expression is necessary to prevent the overproduction of insulin.

[The table below describes the action of two genes involved in the regulation of nervous system development in the nematode C. elegans.] Which of the following claims is best supported by the data? Responses

Gene A promotes neuron development; gene B promotes programmed cell death in neuronal precursors.

The table shows the changes in allele frequencies of a specific gene in two populations of randomly mating small mammals after 30 years. The populations inhabit adjacent equatorial islands that have similar topography and climate. Which of the following is the most reliable conclusion that can be drawn from analysis of the data above?

Genetic drift has occurred in population 1.

Which of the following best supports the claim that organisms of different domains share a common ancestor?

Glycolysis occurs in both prokaryotic cells and eukaryotic cells

An increase in the concentration of protons in the cytosol will most likely have which of the following effects on glycolysis?

Glycolytic enzymes will denature as a result of the increased H+H+concentration.

A researcher measured the temperature at which two different samples of double-stranded DNADNA denature (separate into single strands). Sample 11 denatured at a significantly lower temperature than sample 22 did. Based on the data, the researcher claims that the DNADNA in sample 22 is composed of a higher percentage of guanine and cytosine than the DNADNA in sample 11 is. Which of the following best supports the researcher's claim?

Guanine-cytosine pairs denature at a higher temperature because they have more hydrogen bonds between them than adenine-thymine pairs do.

One model of a sustainable fisheries practice is for individual fish to be removed from a natural population at a rate equal to the highest possible growth rate of an ideal population. The graph above represents a population of bluefin tuna living along the Atlantic coast. At which labeled point in the graph is the population growth rate the highest?

III

(AVERAGE CHANGE IN pHpH IN CONTROL AND TREATMENT GROUPS OVER A 4040-MINUTE PERIOD) Which of the following graphs best represents the data in Table 1 ?

IMAGE Connected Line

Which of the following graphs is the most appropriate representation of the experimental data?

IMAGE filled in bar graph

[Figure 2. FXN��� gene fragment sizes for several family members. A sample of DNADNA with fragments of known lengths was used for comparison.] Which of the following statements best describes the results seen in Figure 2 ?

Individuals III-2III-2 and III-3III-3 carry two different alleles of the FXN��� gene, a mutant allele and a wild-type allele. Individual IV-1IV-1 inherited two copies of the mutant allele.

While there is only one species of Galápagos Island tortoise, there are several subspecies. Larger islands with more wet highlands have lush vegetation near the ground. Tortoises there tend to have high-domed shells and shorter necks, which restrict upward head movement. They also have shorter limbs. They are the heaviest and largest of the subspecies. Smaller, drier islands are inhabited by tortoises with longer necks and limbs and with shells that are elevated above the neck, which allow them to browse taller vegetation. Based on the information given, which of the following is a plausible explanation for the ancestry of the tortoise subspecies?

Individuals with different adaptations in shell shape and leg length best exploited the food resources and left more surviving offspring on each island.

Chytridiomycosis is a potentially lethal fungal infection that adversely affects some frog populations. The incidence and severity of the fungal infection can vary over time. Which of the following statements best describes the changes in the frog population that are depicted in the model above?

Infected individuals gradually died out, and genetically resistant individuals became more common. The frog population recovered because of the increased frequency of resistant individuals.

[Individuals of a particular species of ground beetle are either light tan or dark brown...] Which of the following can be inferred from the data in the table?

Insectivorous birds are predators of this species of ground beetle.

Researchers analyzed the amino sequence of the protein cytochrome c� in various groups of organisms and determined the number of amino substitutions that have occurred in the different groups of organisms. They plotted the data with respect to the time since divergence of the members of paired groups from a common ancestor (Figure 1). Based on the data, which of the following organisms are most distantly related?

Insects and vertebrates

Pesticides are chemicals that are often sprayed on crops to kill plant-eating insects, preventing damage to the crops. While pesticides are effective initially, many researchers claim that any single pesticide will see reduced effectiveness in as little as ten to fifteen years. Which of the following best supports the claim by scientists that the pesticides will eventually lose their effectiveness?

Insects that are naturally resistant to the pesticide will survive and reproduce more than the insects that are sensitive to the pesticide.

On a large volcanic island, researchers are studying a population of annual herbaceous plants. Which of the following observations best supports the prediction that speciation will occur within the existing plant population?

Lava has separated the population into two areas: an upland forest and a lowland marsh.

Which of the following combinations of flies showed the highest number of mating instances?

Males grown on starch paired with females grown on starch

Which of the following best describes the reproductive ability of C. elegans following the ARDARD induced in the first experiment?

Mating with a well-fed male consistently produced more offspring than did reproduction via self-fertilization.

These cells are the result of nondisjunction during which of the following phases?

Meiosis I

Based on Figure 2, which of the following best supports the claim that drug X inhibits oxygen consumption? Responses

Melanoma line 33 consumes statistically less oxygen per cell in the presence of drug XX than it does in the presence of the solvent alone.

Which of the following is the strongest evidence supporting the endosymbiont hypothesis?

Mitochondria have their own DNADNA and divide independently of the cell.

Which of the following is the most likely effect of a mutation in the gene coding for a DNA repair enzyme?

Mutations will accumulate more quickly because the cell will not be able to fix errors in replication.

The pesticide DDT was widely used in the 1940s as a method of insect control. In the late 1950s the first DDT-resistant mosquitoes were discovered, and eventually DDT-resistant mosquitoes were found globally. When DDT is used now, the development of DDT resistance in mosquito populations occurs in months rather than years. Which of the following best explains the observations concerning DDT resistance in mosquitoes?

Natural selection favors DDT-resistant mosquitoes that are already present in a population when DDT exposure occurs.

In an investigation of interspecies competition, researchers grew the unicellular protozoan Paramecium aurelia in a 5 mL culture and Paramecium caudatum in a separate 5 mL culture. P. aurelia and P. caudatum were grown together in a third 5 mL culture. Each day a small sample of each culture was removed so the total number of individuals could be estimated, and the remainder of the population was transferred to fresh growth medium. The experimental results are represented in the graphs below. Which of the following conclusions is best supported by the results of the experiment?

Neither population grows as large when cultured together as each does when cultured separately.

Which of the following communities is likely to be most stable?

One with high species diversity

[BACTERIAL GROWTH FOLLOWING TRANSFORMATION WITH OR WITHOUT THE KANAMYCIN RESISTANCE GENE] Which of the following claims is best supported by the data in Table 1 ?

Only the bacteria that were successfully transformed with the kanamycin resistance gene grew on plate 44.

Membrane-bound organelles have been an important component in the evolution of complex, multicellular organisms. Which of the following best summarizes an advantage of eukaryotic cells having internal membranes?

Organelles isolate specific reactions, increasing metabolic efficiency.

In a species of cactus, the number of spines on a plant is genetically determined. The graph above shows frequency distributions for populations of the cactus species growing in the presence or absence of two herbivores: peccaries (a New World pig) and wasp larvae. Which of the following best accounts for the different frequency distributions in the graph?

Peccaries eat cacti with a smaller number of spines, and wasp larvae eat cacti with a greater number of spines.

Trypsin and pepsin are enzymes that function in different areas of the digestive tract. One functions in the stomach, where the pHpH is between 1.51.5 and 3.53.5, while the other functions in the small intestines, where the pHpH is between 66 and 88. Based on Figure 1, which of the following best describes where each enzyme functions?

Pepsin works in the stomach because the optimal pHpH for pepsin is acidic.

Which of the following samples most likely contains a double-stranded RNARNA virus?

Sample 1

[TABLE 1. PERCENT CHEMICAL COMPOSITION OF FOUR MACROMOLECULES] Which of the following claims is best supported by the data in Table 1 ?

Sample B contains protein.

Based on the data in the table, which of the following lizard species are most closely related?

Species EE and species D

What is the frequency of the recessive allele?

Square root of 0.25

The drug 5-fluorouracil inhibits thymine production in eukaryotic cells. Which of the following cell cycle stages will be most directly affected by 5-fluorouracil? Responses

Synthesis of DNA phase (SS)

The data above represent the results of three different crosses involving the inheritance of a gene that determines whether a certain organism is blue or white. Which of the following best explains the mechanism of inheritance of the gene?

The allele for blue is an X-linked dominant allele because there are no blue male offspring in cross 2.

Developers have approved a project that will permanently reduce the primary producers' biomass by 50 percent and remove all rabbits and deer. Which of the following is the most likely result at the completion of the project? Responses

The biomass of coyotes will be dramatically reduced.

Figure 1. Replicated DNA produced after a chemical is introduced Which of the following claims is best supported by the data?

The chemical inhibits DNADNA ligase.

Humans have a diploid number (2n) of 46. Which of the following statements best predicts the consequence if meiosis did not occur during gametogenesis?

The chromosome number would double with each generation.

The figure shows a phylogenetic tree of various members of the order Proboscidea, which includes modern elephants. Which of the following claims is best supported by the information in the figure ? Responses

The common ancestor of the African elephant and the mastodon is the Palaeomastodon.

Which of the following describes the relationship between the amount of chlorophyll a in a water sample and the concentration of nitrogen in that sample?

The concentrations of nitrogen and chlorophyll a are directly correlated.

In an experiment, the efficiency of oxygen exchange across the plasma membrane is being assessed in four artificial red blood cells. The table above lists some properties of those artificial cells. Other conditions being equal, which artificial cell is predicted to be the most efficient in exchanging oxygen with the environment by diffusion?

The cuboidal cell

Arctic foxes typically have a white coat in the winter. In summer, when there is no snow on the ground, the foxes typically have a darker coat. Which of the following is most likely responsible for the seasonal change in coat color? Responses

The decrease in the amount of daylight in winter causes a change in gene expression, which results in the foxes growing a lighter-appearing coat.

Mercurial sulfhydryl is an inhibitor of aquaporins. Which of the following is the most likely effect of adding mercurial sulfhydryl to the distilled water solution?

The grape cells will gain water more slowly because of a lack of facilitated diffusion.

Which of the following predicts the most likely ecological problem that would occur if guppies are introduced into new areas to control the mosquito population?

The guppies might have no natural predators, which will result in a dramatic increase in the guppy population and an increase in competition for other native species.

The amino acid sequence of cytochrome c is exactly the same in humans and chimpanzees. There is a difference of 13 amino acids between the cytochrome c of humans and dogs, and a difference of 20 amino acids between the cytochrome c of humans and rattlesnakes. Which of the following statements is best supported by these data?

The human is apparently more closely related to the chimpanzee than to the dog or rattlesnake.

Based on the data in Table 1, which of the following best evaluates the student's hypothesis?

The hypothesis is not supported because the mass of the grape increased in the grape juice.

Modern bananas originated from a cross between a tetraploid banana species and a diploid banana species. The product of this cross was the triploid Cavendish banana strain, a sterile hybrid that is only grown asexually. Recently, the Panama fungus has been observed more frequently parasitizing the Cavendish banana, and scientists claim that this type of banana is on the brink of extinction. Which of the following provides the best explanation of the scientists' claim regarding the threat to the Cavendish banana?

The lack of genetic diversity of the Cavendish banana decreases the chance that a variation exists in the population that is immune to the fungus.

By discharging electric sparks into a laboratory chamber atmosphere that consisted of water vapor, hydrogen gas, methane, and ammonia, Stanley Miller obtained data that showed that a number of organic molecules, including many amino acids, could be synthesized. Miller was attempting to model early Earth conditions as understood in the 1950s. The results of Miller's experiments best support which of the following hypotheses?

The molecules essential to life today could have formed under early Earth conditions.

Based on the information provided, which of the following best justifies the claim that osteocalcin is a hormone?

The osteoblasts in the bone secrete osteocalcin, which causes cells in the pancreas to change their activity.

Which of the following observations provides the best evidence that acetyl-CoA negatively regulates pyruvate dehydrogenase activity?

The rate of the pyruvate dehydrogenase-catalyzed reaction is slower in the presence of a higher concentration of acetyl-CoACoA.

The following the DNA sequence is a small part of the coding (nontemplate) strand from the open reading frame of β-hemoglobin gene. Given the codon chart listed below, what would be the effect of a mutation that deletes the G at the beginning of the DNA sequence?

The reading frame of the sequence would shift, causing a change in the amino acid sequence after that point.

Undersea landslides can disrupt marine habitats by burying organisms that live on the ocean floor. The graph above shows the size of a population of a certain organism that lives on the ocean floor. The population was affected by a recent landslide at the time indicated on the graph. Which of the following best predicts how the population will be affected by the landslide?

The reduced population will likely have allelic frequencies that are different from the initial population.

After a search of nucleotide sequence databases, researchers identified an IRE in the 5¢ untranslated region of a gene encoding aconitase, an enzyme involved in the Krebs cycle. Which of the following pieces of experimental evidence best supports the claim that the synthesis of aconitase is controlled by a mechanism similar to ferritin regulation?

The relative amount of aconitase protein increases in the presence of high levels of iron.

Which of the following is a valid interpretation of the experimental results that explains how individuals with type 2 diabetes differ from individuals without diabetes?

The relatively low levels of glucose uptake in individuals with type 2 diabetes indicate that mobilization of GLUT4 to the cell surface is reduced in muscle cells of those individuals.

Which of the following best describes the scientists' findings concerning the density of symbionts presented in Figure 2 ?

The symbiont density at 32°C32°C was different from the density at 27°C27°C on days 55 and 1010 of the experiment. D

Which of the following is the most likely explanation of the results?

The two genes are linked on an autosome.

For following group of questions first study the description of the situation and then choose the one best answer to each question following it and fill in the corresponding oval on the answer sheet. A survey reveals that 25 percent of a population of 1,000 individuals have attached earlobes (are homozygous recessivefor the trait). For the following questions, assume that the population fits the parameters of the Hardy-Weinberg law. Question Unlike most natural populations, this population is best characterized in which of the following ways? Responses

There is genetic equilibrium.

Which of the following best explains the most likely method by which this antitumor drug works?

Trabectedin interferes with the duplication of DNADNA during interphase and thus prevents cancer cells from passing the G2G2 checkpoint.

MRSA is the acronym for methicillin-resistant Staphylococcus aureus. Many of the strains of the common bacterium are also resistant to other antibiotics in use today. The resistance is linked to a collection of genes carried on plasmids that are passed from one bacterium to another by conjugation. Suppose a newly discovered, chemically different antibiotic is used in place of methicillin. Which of the following would be the most likely effect on Staphylococcus aureus antibiotic resistance?

Transmission of the methicillin-resistance plasmid would gradually decrease but the plasmid would not entirely disappear from the Staphylococcus aureus population.

Figure 1 shows the relative rates of transpiration (water loss) and water intake for a plant over an 1818-hour period. Which of the following describes the most likely relationship between transpiration and water intake in the plant? Responses

Transpiration from the leaves of the plant stimulates subsequent water intake by the roots of the plant.

The student analyzed the data from the investigation and concluded that the estimate of the mean of one treatment group was unreliable. Which of the following identifies the treatment group most likely to have provided an unreliable estimate of the mean, and correctly explains why the estimate appears unreliable?

Treatment group II; it has a lower than expected mean absorbance and the largest standard error of the mean.

A scientist is developing a mathematical model of cells of different shapes. To construct the model, the scientist has specified that the width of each cell at its widest point must be 30μm30μm and the height of each cell must be 90 μm90 μm. Table 1 shows the three-dimensional shapes that the scientist is considering for the model cells. Which of the proposed shapes for the model cells will allow the most efficient exchange of materials with the surrounding environment? Responses

Triangular prism

To investigate the effects of ground-level ozone pollution on different species of plants, researchers recorded the number of plants in a certain area that had ozone-induced leaf damage. Based on the results of the survey shown in Table 1, which of the following plant species was most affected by ozone pollution?

Wild grape

A mutation in the upland cotton plant causes the development of chloroplasts with a single outer membrane and no internal membranes. Which of the following would most likely be observed in chloroplasts of cotton plants with this mutation?

hey would be unable to generate the ATPATP and NADPHNADPH needed to make sugars, because these processes occur on membranes within the chloroplast.

According to the results of this experiment, germination of tobacco seeds during the first week is Responses

increased by exposure to light

[Figure 1. Absorbance readings of four prepared tubes with various solutions over a 6060-minute period.] Which of the following claims is best supported by the experimental results?

light is required for the electron transport chain to transfer electrons.

In the Arctic Ocean, the predominant primary producers are phytoplankton. Phytoplankton are consumed by zooplankton, which in turn are eaten by codfish. In years when there is more open water (less ice coverage), there are more zooplankton and fish than in years with less open water (more ice coverage). Based on the graph above, the difference is most likely because

the ice blocks the light, so in years with more ice coverage, there is less photosynthesis by the phytoplankton

There are white-eyed females in the F2 generation because

these F2 females have two white alleles