Cartilage

What is the proteoglycan core of the matrix?

Aggrecan

Which cartilage is perichondrium absent from?

Articular hyaline cartilage Fibrocartilage

Where is elastic cartilage found?

Auricle, epiglottis, parts of the larynx, Eustachian tube

What type of collagen makes up fibrocartilage?

Course collagen type I

Which cartilage has chondrocytes seen individually or in isogenous groups arranged in long rows?

Fibrocartilage

Which cartilage has no recognizable perichondrium?

Fibrocartilage

Which cartilage can have an alternative pattern?

Fibrocartilage (herringbone in IVD)

What are chondrocytes?

Mature cells that become trapped in individual lacunae

What are the three types of cartilage cells?

Chondrogenic Chondroblasts Chondrocytes

Which glycoprotein binds the chondrocytes to the matrix?

Chondronectin

What are the GAG's in the matrix?

Chondrotin sulfate Keratan sulfate Hyaluronic acid

What is the perichondrium? What type of collagen is it composed of?

Dense fibrous sheath composed of collagen type I

Which cartilage has a yellowish color when fresh?

Elastic

What is 95% of cartilage tissue made up of? What is is devoid of?

Gel-like extracellular matrix It is avascular, with no nerves or lymphatics

What are GAG's?

Glycosoaminoglycans

What is the most abundant type of cartilage?

Hyaline

Which cartilage appears blueish-white when fresh?

Hyaline

Which cartilage serves as the temporary skeleton in the embryo?

Hyaline

Where is fibrocartilage found?

IVD, pubic symphysis

What are the two layers of the perichondrium?

Inner chondrogenic layer Outer dense irregular CT layer with fibroblasts and blood vessels

Where are chondrogenic cells found?

Inner layer of Perichondrium

What are three types of growth of cartilage?

Interstitial Appositional Regeneration (limited)

How do cartilage plates expand?

Interstitial growth

What is the function of chondroblasts?

Manufacture the matrix

What is the function of cartilage?

Supports soft tissues, Facilitates smooth movement of joints, Involved in the growth of long bones,

What type of collagen makes up the matrix?

Type II embedded in a hydrated gel

How do isogenous groups form?

When chondrocytes go through mitosis