Ch 14 Practice Questions

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The better the patient's oral hygiene is, the less likely that lesions associated with use of phenytoin will occur.

True

Each of the following is an example of a type of generalized seizure except one. Which is the exception?

Simple

Which is the most important drug interaction of antiepileptic drugs?

Stimulation of hepatic microsomal enzymes

Which of the following statements is true concerning epilepsy?

The majority of epileptic patients have idiopathic epilepsy.

Each of the following statements is true of absence seizures except one. Which is the exception?

To avoid trauma, tongue blades should not be used in the oral cavity.

Which of the following drugs is often used first for treating patients with generalized tonic-clonic seizures even though it is not Food and Drug Administration (FDA) approved for this use?

Valproate

The drug of choice for treatment of absence seizures is

ethosuximide

Ethosuximide is the drug of choice for the treatment of _____ seizures.

generalized absence

The mechanism of action of vigabatrin is thought to be

irreversible inhibition of GABA.

Gingival enlargement as a consequence of phenytoin therapy most commonly affects the __________ facial gingiva

maxillary anterior

Surgical intervention to reduce phenytoin-induced gingival enlargement should wait until at least 18 months after cessation of therapy because

some patients experience additional reduction in the enlargement after the 1-year period.

Seizures characterized by a duration for longer than 30 minutes are called _____ seizures.

status epilepticus

A patient experiencing tonic-clonic seizures should be managed by

tilting the patient's head to one side to prevent aspiration.

The cause of phenytoin gingival enlargement is

unknown

Clonazepam (Klonopin) is

used as an adjunct to treat ethosuximide-resistant absence seizures.

Gingival enlargement may occur in what percentage of chronic users of phenytoin?

50%

Lamotrigine is an effective treatment for myoclonic seizures.

True

Valproate is associated with toxicity of which of the following organs?

Liver

____ is noted for having cross-sensitivity with carbamazepine in 20% to 30% of patients.

Oxcarbazepine

Fetal hydantoin syndrome is associated with maternal ingestion of

Phenytoin

Which agent has a narrow therapeutic index because its metabolism is a saturable process?

Phenytoin

Which antiepileptic medication has been known to produce osteomalacia?

Phenytoin

Which of the following seizures are categorized as generalized seizures?

Absence seizures Simple (Jacksonian) seizures

Alopecia may be observed as an adverse effect of phenytoin. Carbamazepine can cause hirsutism.

Both statements are false

Performing laboratory tests is necessary to monitor patients who are taking carbamazepine. The dental team should observe the oral cavity for petechiae or signs of infections.

Both the statement and the reason are correct and related.

Which of the following statements is true of absence seizures and tonic-clonic seizures?

Both types of seizures involve the loss of consciousness.

Which of the following statements is true regarding adverse reactions to antiepileptic agents?

CNS depression is a common side effect of antiepileptic agents.

Which antiepileptic agent is commonly prescribed for trigeminal neuralgia?

Carbamazepine

Which of the following antiepileptics may be used to manage trigeminal neuralgia?

Carbamazepine

Which of the following agents interferes with platelets?

Carbamazepine Valproic acid

Which of the following antiepileptic drugs is commonly used as monotherapy for partial onset and generalized tonic-clonic seizures and may be effective for children with Lennox-Gastaut syndrome?

Levetiracetam (Keppra)

Each of following is considered a drug of choice for treatment of generalized tonic-clonic seizures except one. Which is the exception?

Eslicarbazepine

Vitamin C is an effective adjunctive therapy for gingival enlargement

False

Lamotrigine (Lamictal) belongs to which of the following classes of antiepileptic drugs?

Inactivates sodium channels


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