Clin path 1

A technician needs to collect 1.5 mL of blood for a specific blood test. Which is the best size syringe to use to collect the sample?Which is the preferred item to use for blood collection?

3 Ml syringe with a purple top tube

A cloudy appearance to the plasma layer of the microhemocrit tube may be an indication of which of the following?

Anemia

A technician is asked to collect a blood sample and perform a manual complete blood count (CBC) and cellular morphology analysis. Which is the preferred anticoagulant for the blood collection?

EDTA

Which term refers to the constant and continual production of red blood cells?

Erythropoiesis

Blood cells are constantly produced and have a finite life span; therefore they need to be continually replaced. Which term identifies the process of the production of blood cells and platelets?

Erythropoiesis and Thrombopoiesis

Which types of white blood cells always contain granules and are commonly referred to as polymorphonuclear leukocytes?

Granulocytes

Which term refers to the process by which neutrophils, eosinophils, and basophils are formed?

Granulopoiesis

Which of the following anticoagulants should not be used if analyzing WBC morphology?

Heparin

A reddish tinge to the whitish gray buffy coat layer in the microhematocrit tube is evidence of what?

Increase of nucleated RBCs

Which type of cytokine is the stimulus for production of granulocytes?

Leukopoietin

Which term indicates a decrease in the number of lymphocytes?

Lymphopenia

Which cell type is not capable of cell division? Note: Hemoglobin formation is completed at this stage and will eventually extrude its nucleus and mature into a reticulocyte.

Metarubricyte

Which of the following cells is the smallest erythroid cell, has a condensed nucleus, and has a deep red cytoplasm?

Metarubricyte

List the order of maturation series of granulocytes beginning with the most immature to the most mature?

Myeloblast, promyleocyte, neutrophilic myelocyte, neutrophilic metamyelocyte, neutrophilic band, neutrophil

At which stage during the granulopoiesis process do the granule characteristics of mature neutrophil, eosinophil, and basophil begin to appear?

Myelocyte

Granule characteristics of the mature neutrophil, eosinophil, and basophil begin to appear at which stage of granulopoiesis?

Myelocyte

Which type of cell will be a large cell containing two to four nuclei and will continually get larger as the nucleus replicates until it is fully mature?

Promegakaryocyte

Which type of cell is a large pale-staining cell with no prominent nucleoli?

Promyelocyte

Which of these cells is a product of megakaryocyte/erythrocyte progenitor cells and has a condensed nucleus and an intensely blue cytoplasm?

Prorubricyte

When stained with new methylene blue, what type of maturing cell will appear to have small dark blue spots in the cytoplasm?

Punctate reticulocyte

Which vacutainer is best suited for the collection of blood for a hematologic test?

Purple top

List the order of the maturation series of erythrocytes beginning with the most immature to the most mature?

Rubiblast, Prorubricyte, Basophilic rubricyte, Polychromatic rubricyte, Metarubricyte, reticulocyte

The common myeloid progenitor (CMP) will produce a megakaryocyte/erythrocyte progenitor. What type of cell produced by the megakaryocyte/erythrocyte progenitor will eventually give rise to erythrocytes?

Rubriblast

Which type of lymphocyte matures only in the thymus?

T lymphocytes

Whole blood is composed of fluid and cells - Name the cells and the fluid.

The fluid is plasma and the cells are RBC, the five WBC, and platelets

Which types of white blood cells may sometimes contain granules, but only in very small numbers, and are referred to as mononuclear leukocytes?

agranulocytes

Which types of cells have a horseshoe-shaped nucleus with parallel sides?

band cells

Chemical messengers, referred to as cytokines, are involved in producing specific blood cell types. Which cytokine is responsible for the production of red blood cells?

erythropoietin

Which process of blood cell and platelet production takes place in the red bone marrow of primarily the long bones in adult animals?

hematopoiesis

Which vessel is the preferred blood source for venous blood in most species?

jugular

Erythropoietin stimulates red blood cell production and is primarily produced in certain cells within which organ in the body?

kidney

Which term best describes the increase in the number of immature neutrophils in the peripheral blood?

left shift

Which term best describes neoplastic cells present in the blood or bone marrow?

leukemia

Which term indicates an increase in the number of leukocytes?

leukocytosis

This cytokine, thrombopoietin, is responsible for the production of thrombocytes in primarily which organ of the body?

liver

The common lymphoid progenitor (CLP) product of the pluripotent hematopoietic stem cell (HSC) eventually gives rise to specific progenitors that develop in various populations of what type of cell?

lymphocytes

Which refers to the process by which lymphocytes are formed?

lymphopoiesis

The common myeloid progenitor (CMP) will produce a megakaryocyte/erythrocyte progenitor. What type of cell produced by the megakaryocyte/erythrocyte progenitor will eventually give rise to platelets?

megakaryoblast

A technician is reviewing a slide made from bone marrow. What is the largest type of cell that is characterized by numerous nuclear lobes and a reddish cytoplasm?

megakaryocyte

Which refers to a very large cell in which the cytoplasm extends into the bone marrow sinuses and shears off into the flow of blood, creating proplatelets?

megakaryocyte

Myeloid cells are large and pale-staining cells. Which type of cell would be a myeloid cell?

monocyte

Macrophages may develop from which type of cell if exposed to a specific cytokine?

monocytes

Which refers to the process by which monocytes are formed?

monopoiesis

Which term indicates a decrease in the number of neutrophils?

neutropenia

Which term indicates a decreased number of all blood cell types?

pancytopenia

Which is the fluid portion of whole blood in which the cells are suspended?

plasma

Which blood components are fragments of the cytoplasm of megakaryocytes?

platelets

Erythrocytes, leukocytes, and platelets all arise from the same type of cell. From what type of cell do these cells originate?

pluripotent hematopoietic stem cell

Which is the fluid part of blood from which fibrinogen has been removed?

serum

Which is the fluid that is squeezed out around the cellular clot when blood clots?

serum

Erythroid cells are small and have clumped basophilic nuclei. Which type of cell would be an erythroid cell?

thrombocyte

Which cytokine is largely responsible for the production of platelets?

thrombopoietin