Clin path 1
A technician needs to collect 1.5 mL of blood for a specific blood test. Which is the best size syringe to use to collect the sample?Which is the preferred item to use for blood collection?
3 Ml syringe with a purple top tube
A cloudy appearance to the plasma layer of the microhemocrit tube may be an indication of which of the following?
Anemia
A technician is asked to collect a blood sample and perform a manual complete blood count (CBC) and cellular morphology analysis. Which is the preferred anticoagulant for the blood collection?
EDTA
Which term refers to the constant and continual production of red blood cells?
Erythropoiesis
Blood cells are constantly produced and have a finite life span; therefore they need to be continually replaced. Which term identifies the process of the production of blood cells and platelets?
Erythropoiesis and Thrombopoiesis
Which types of white blood cells always contain granules and are commonly referred to as polymorphonuclear leukocytes?
Granulocytes
Which term refers to the process by which neutrophils, eosinophils, and basophils are formed?
Granulopoiesis
Which of the following anticoagulants should not be used if analyzing WBC morphology?
Heparin
A reddish tinge to the whitish gray buffy coat layer in the microhematocrit tube is evidence of what?
Increase of nucleated RBCs
Which type of cytokine is the stimulus for production of granulocytes?
Leukopoietin
Which term indicates a decrease in the number of lymphocytes?
Lymphopenia
Which cell type is not capable of cell division? Note: Hemoglobin formation is completed at this stage and will eventually extrude its nucleus and mature into a reticulocyte.
Metarubricyte
Which of the following cells is the smallest erythroid cell, has a condensed nucleus, and has a deep red cytoplasm?
Metarubricyte
List the order of maturation series of granulocytes beginning with the most immature to the most mature?
Myeloblast, promyleocyte, neutrophilic myelocyte, neutrophilic metamyelocyte, neutrophilic band, neutrophil
At which stage during the granulopoiesis process do the granule characteristics of mature neutrophil, eosinophil, and basophil begin to appear?
Myelocyte
Granule characteristics of the mature neutrophil, eosinophil, and basophil begin to appear at which stage of granulopoiesis?
Myelocyte
Which type of cell will be a large cell containing two to four nuclei and will continually get larger as the nucleus replicates until it is fully mature?
Promegakaryocyte
Which type of cell is a large pale-staining cell with no prominent nucleoli?
Promyelocyte
Which of these cells is a product of megakaryocyte/erythrocyte progenitor cells and has a condensed nucleus and an intensely blue cytoplasm?
Prorubricyte
When stained with new methylene blue, what type of maturing cell will appear to have small dark blue spots in the cytoplasm?
Punctate reticulocyte
Which vacutainer is best suited for the collection of blood for a hematologic test?
Purple top
List the order of the maturation series of erythrocytes beginning with the most immature to the most mature?
Rubiblast, Prorubricyte, Basophilic rubricyte, Polychromatic rubricyte, Metarubricyte, reticulocyte
The common myeloid progenitor (CMP) will produce a megakaryocyte/erythrocyte progenitor. What type of cell produced by the megakaryocyte/erythrocyte progenitor will eventually give rise to erythrocytes?
Rubriblast
Which type of lymphocyte matures only in the thymus?
T lymphocytes
Whole blood is composed of fluid and cells - Name the cells and the fluid.
The fluid is plasma and the cells are RBC, the five WBC, and platelets
Which types of white blood cells may sometimes contain granules, but only in very small numbers, and are referred to as mononuclear leukocytes?
agranulocytes
Which types of cells have a horseshoe-shaped nucleus with parallel sides?
band cells
Chemical messengers, referred to as cytokines, are involved in producing specific blood cell types. Which cytokine is responsible for the production of red blood cells?
erythropoietin
Which process of blood cell and platelet production takes place in the red bone marrow of primarily the long bones in adult animals?
hematopoiesis
Which vessel is the preferred blood source for venous blood in most species?
jugular
Erythropoietin stimulates red blood cell production and is primarily produced in certain cells within which organ in the body?
kidney
Which term best describes the increase in the number of immature neutrophils in the peripheral blood?
left shift
Which term best describes neoplastic cells present in the blood or bone marrow?
leukemia
Which term indicates an increase in the number of leukocytes?
leukocytosis
This cytokine, thrombopoietin, is responsible for the production of thrombocytes in primarily which organ of the body?
liver
The common lymphoid progenitor (CLP) product of the pluripotent hematopoietic stem cell (HSC) eventually gives rise to specific progenitors that develop in various populations of what type of cell?
lymphocytes
Which refers to the process by which lymphocytes are formed?
lymphopoiesis
The common myeloid progenitor (CMP) will produce a megakaryocyte/erythrocyte progenitor. What type of cell produced by the megakaryocyte/erythrocyte progenitor will eventually give rise to platelets?
megakaryoblast
A technician is reviewing a slide made from bone marrow. What is the largest type of cell that is characterized by numerous nuclear lobes and a reddish cytoplasm?
megakaryocyte
Which refers to a very large cell in which the cytoplasm extends into the bone marrow sinuses and shears off into the flow of blood, creating proplatelets?
megakaryocyte
Myeloid cells are large and pale-staining cells. Which type of cell would be a myeloid cell?
monocyte
Macrophages may develop from which type of cell if exposed to a specific cytokine?
monocytes
Which refers to the process by which monocytes are formed?
monopoiesis
Which term indicates a decrease in the number of neutrophils?
neutropenia
Which term indicates a decreased number of all blood cell types?
pancytopenia
Which is the fluid portion of whole blood in which the cells are suspended?
plasma
Which blood components are fragments of the cytoplasm of megakaryocytes?
platelets
Erythrocytes, leukocytes, and platelets all arise from the same type of cell. From what type of cell do these cells originate?
pluripotent hematopoietic stem cell
Which is the fluid part of blood from which fibrinogen has been removed?
serum
Which is the fluid that is squeezed out around the cellular clot when blood clots?
serum
Erythroid cells are small and have clumped basophilic nuclei. Which type of cell would be an erythroid cell?
thrombocyte
Which cytokine is largely responsible for the production of platelets?
thrombopoietin