CYP3A4 inhibitors and inducers
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Inhibitors Mnemonic
G PACMAN
Oxcarbazepine
Inducer
Phenobarbital
Inducer
Phenytoin
Inducer
Rifampin, Rifabutin, Rifapentine
Inducer
Smoking
Inducer
St. John's Wort
Inducer
Carbamazepine
Inducer and auto-inducer
-Azole antifungals
Inhibitor
Amiodarone
Inhibitor
Cyclosporine and Cimetidine (H2RA)
Inhibitor
Grapefruit
Inhibitor
Macrolides
Inhibitor
Non-DHP CCBs (verapamil, diltiazem)
Inhibitor
Protease Inhibitors (-navirs)
Inhibitor
Inducers Mnemonic
PS PORCS