MC - Pharmaceutics II Exam 2

Vyvanse is a Prodrug that gets metabolized into what 2 metabolites? A. d-amphetamine + l-lysine B. l-amphetamine + d-amphetamine C. d-amphetamine + v-lysine D. l-amphetamine + l-lysine

A. d-amphetamine + l-lysine

What is the ingredient croscarmellose sodium used for in making acetaminophen tablets? A. disintegrant B. filler C. solubilizer D. coloring agent

A. disintegrant

What role does the ingredient hydrated silica have? A. water absorbant B. disintegrant C. API D. binder

A. water absorbant

What is the main role of the sugar spheres in Metadate CD capsules? A. API B. filler C. disintegrant D. solution binder

B. filler

Which method involves dissolving the API into a melted base and then transferring the ingredients into molds? A. dry granulation B. fusion molding C. direct compression D. wet granulation

B. fusion molding

What is the role of talc in the formulation of Danazol hard capsules? A. to ensure disintegration of powder mixture (disintegrant) B. improve powder flow properties (glidant) C. improved flow properties and reduced powder adhesion to metal parts (lubricant) D. improve plug formation and compression (diluent)

B. improve powder flow properties (glidant)

What is an advantage of Lamprene dosage form (soft gelatin capsule?) A. less expensive to formulate B. increase bioavailability C. increased stability D. all of the above

B. increase bioavailability

What is the API in Oxecta? A. magnesium stearate B. oxycodone hydrochloride C. crospovidone D. polyethylene oxide

B. oxycodone hydrochloride

What is the therapeutic class of Nurtec? A. agent for gout B. treatment for acute migraine C. antihypertensive D. analgesic

B. treatment for acute migraine

What is the purpose of the PEG hydrogel in Dextenza? A. colorant B. vehicle C. buffering agent D. opacifier

B. vehicle

What is the point of advice that is TRUE for patients taking Oxecta? A. alcohol use is not an issue when taking Oxecta B. it is okay to crush the tablet if the patient has a hard time swallowing pills C. Oxecta should never be stopped abruptly D. if a dose is missed, take it with the next dose

C. Oxecta should never be stopped abruptly

Which ingredient is essential in the controlled release timing of Lamprene (soft gelatin capsule)? A. citric acid B. parabens C. beeswax D. ethyl vanillin

C. beeswax

What is the mechanism of action of Nurtec? A. opioid receptor agonist B. inhibits prostaglandin synthesis through inhibition of cyclooxygenases C. calcitonin-gene related peptide receptor antagonist D. inhibits xanthine oxidase

C. calcitonin-gene related peptide receptor antagonist

The ingredient's "titanium dioxide" and "yellow ferric oxide" act as ___ in the formulation of avigan tablets A. surfactants B. sweeteners C. colorants D. plasticizers

C. colorants

Which of the following characteristics/effects of Danazol is correct? A. stimulates an overall increase to estrogen production B. danazol has been found to have low permeability and high solubility C. effect of pituitary gland, which results in reduced FSH and LH production D. used to increase the growth rate of breast tissue

C. effect of pituitary gland, which results in reduced FSH and LH production

Which of these is the primary reason for why it is possible for vyvanse to have a chewable dosage form? A. contains no excipients B. white in color C. not metabolized into active form until after it is absorbed by gut D. small in size

C. not metabolized into active form until after it is absorbed by gut

What is the indication for Dextenza? A. conjunctivitis B. corneal laceration C. post-op ophthalmic surgery inflammation of the eye and pain D. fungal infection of the eye

C. post-op ophthalmic surgery inflammation of the eye and pain

Which of the following describes proper storage techniques for Annovera? A. store in direct sunlight B. store in a freezer or refrigerator C. store at room temperature D. store very high temperatures

C. store at room temperature

Which of the following is the best option for storage of suboxone? A. store in cold, damp area with little sunlight B. store in fridge C. store in dry, room temperature places D. store in cold, dry area with little sunlight

C. store in dry, room temperature places

Which method of tablet production is used to make acetaminophen tablets? A. direct compression B. dry granulation C. wet granulation D. all of the above

C. wet granulation

Which of the following best describes the correct length of effectiveness of one Annovera? A. 1 month B. 3 months C. 6 months D. 1 year

D. 1 year

Hydroxychloroquine's FDA approved indications include which of the following? A. malaria B. RA C. systemic lupus erythematosus D. all of the above

D. all of the above

What purpose does silicon dioxide serve in Anusol-HC? A. viscosity agent B. slow dispersion of API in the body C. excipient D. all of the above

D. all of the above

Why is Metadate CD preferred over IR formulations of Methylphenidate HCl? A. higher adherence B. once a day dosing instead of multiple times per day C. less fluctuation of plasma concentration D. all of the above

D. all of the above

What is the role of the benzalkonium chloride in the preparation of Rhopressa solution? A. lubricant B. wetting agent C. pore-forming agent D. antibacterial preservative E. diluent

D. antibacterial preservative

What are the advantages to using suboxone sublingual films? A. they have increased bioavailability as compared to SL tablets B. you can take a much lower dose when switching from SL tablets C. they help to deter abuse D. both A and C are correct

D. both A and C are correct

What formulation method is used to produce Cleocin Ovules? A. film coating method B. wet granulation C. hard gelatin capsule D. fusion molding

D. fusion molding

A major benefit of Rhopressa as an ophthalmic solution include all of the following EXCEPT? A. a half-life long enough to allow once daily administration B. localization to the eye because of selective metabolites C. decreased systemic absorption D. increased systemic absorption E. ingredients bypass first pass metabolism

D. increased systemic absorption

Which statement is true? A. the capsule formulation of Avigan increased bioavailability B. the capsule formulation of Avigan decreased bioavailability C. the tablet formulation of Avigan increased bioavailability D. no change in bioavailability between capsule and tablet formulations

D. no change in bioavailability between capsule and tablet formulations

What is the use of titanium dioxide in hydroxychloroquine tablets? A. binder B. coating agent C. lubricant D. prevent light degradation

D. prevent light degradation