Microbiology Chapter 15 Connect Questions

Which of the following are Secondary Lymphoid organs (Areas where mature lymphocytes become activated)? 1. Bone Marrow 2. Thymus 3. Lymph Node 4. Peyer's Patches 5. Tonsils. 6. Mucosa-assoiated lymphoid tissue (MALT)

1. Bone Marrow 2. Lymph Noded 3. Peyer's Patches 4. Tonsils. 5. MALT

After helper T-cell activation, which of the following are produced? 1. Cytokines 2. Th and Tc cells 3. Th effector cells and Th memory cells. 4. Th cells and B cells. 5. Th plasma cells and Th memory cells.

1. Cytokines 2. Th Effector cells and Th memory cells

Cytotoxic T Cells?

1. Recognizes antigens presented on MHC Class I molecules. 2. Also called CD8 T cells. 3. Reponds to endogenous antigens. 4. Not targeted by HIV. 5.Destroys target cells by releasing "death packages"

Helper T Cells?

1. Recognizes antigens presented on MHC Class II molecules. 2. Also called CD4 T cells. 3. Responds to exogenous antigens. 4. Can be targeted by HIV 5. Release cytokines to reactivate B cells or macrophages.

Place the following statements in order (1 to 5). A. Activated T cells proliferate and differentiate. Anergic T cells undergo apoptosis. B. Antigen fragments are presented on MHC molecules on the dendritic cell cytoplasmic membrane. C. Naive T cells recognize and bind the antigen-MHC complexes on dendritic cells also displaying co-stimulary molecules. D. Dendritic cells recognize and take up antigen.

D B C A

TRUE OR FALSE B lymphocytes cannot produce and secrete antibody without the assistance of helper T lymphocytes.

FALSE

TRUE OR FALSE Dendritic cells can only present antigenic epitopes to T cells by losing them into MHC Class II molecules on the dendritic cell surface.

FALSE

You would be more susceptible to viral infections.

If your cell-mediated immune response were compromised?

Most abundant class overall, but mainly found in mucosal secretions. Generally found as a dimer.

IgA

Involved in maturation of B lymphocytes and antibody responses, but function is largely uncharacterized.

IgD

Binds via Fc region to mast cells/basophils. Involved in allergic responses and responses to parasites.

IgE

Main class found in blood . Only class that can cross the placenta. Found as a monomer.

IgG

First class produced in primary response Forms a pentamer. Helps activate complement through the classical pathway.

IgM

TRUE OR FALSE Memory B cells are formed during the primary response so that upon secondary antigen exposure, a faster and more vigorous antibody response ensues.

TRUE