Microbiology Chapter 15 Connect Questions

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Which of the following are Secondary Lymphoid organs (Areas where mature lymphocytes become activated)? 1. Bone Marrow 2. Thymus 3. Lymph Node 4. Peyer's Patches 5. Tonsils. 6. Mucosa-assoiated lymphoid tissue (MALT)

1. Bone Marrow 2. Lymph Noded 3. Peyer's Patches 4. Tonsils. 5. MALT

After helper T-cell activation, which of the following are produced? 1. Cytokines 2. Th and Tc cells 3. Th effector cells and Th memory cells. 4. Th cells and B cells. 5. Th plasma cells and Th memory cells.

1. Cytokines 2. Th Effector cells and Th memory cells

Cytotoxic T Cells?

1. Recognizes antigens presented on MHC Class I molecules. 2. Also called CD8 T cells. 3. Reponds to endogenous antigens. 4. Not targeted by HIV. 5.Destroys target cells by releasing "death packages"

Helper T Cells?

1. Recognizes antigens presented on MHC Class II molecules. 2. Also called CD4 T cells. 3. Responds to exogenous antigens. 4. Can be targeted by HIV 5. Release cytokines to reactivate B cells or macrophages.

Place the following statements in order (1 to 5). A. Activated T cells proliferate and differentiate. Anergic T cells undergo apoptosis. B. Antigen fragments are presented on MHC molecules on the dendritic cell cytoplasmic membrane. C. Naive T cells recognize and bind the antigen-MHC complexes on dendritic cells also displaying co-stimulary molecules. D. Dendritic cells recognize and take up antigen.

D B C A

TRUE OR FALSE B lymphocytes cannot produce and secrete antibody without the assistance of helper T lymphocytes.

FALSE

TRUE OR FALSE Dendritic cells can only present antigenic epitopes to T cells by losing them into MHC Class II molecules on the dendritic cell surface.

FALSE

You would be more susceptible to viral infections.

If your cell-mediated immune response were compromised?

Most abundant class overall, but mainly found in mucosal secretions. Generally found as a dimer.

IgA

Involved in maturation of B lymphocytes and antibody responses, but function is largely uncharacterized.

IgD

Binds via Fc region to mast cells/basophils. Involved in allergic responses and responses to parasites.

IgE

Main class found in blood . Only class that can cross the placenta. Found as a monomer.

IgG

First class produced in primary response Forms a pentamer. Helps activate complement through the classical pathway.

IgM

TRUE OR FALSE Memory B cells are formed during the primary response so that upon secondary antigen exposure, a faster and more vigorous antibody response ensues.

TRUE


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