Nutrition Chapter 5 Digestion, Absorption, & Metabolism
treat galactosemia
A strict galactose-free diet
Glycogen storage disease ( GSD) (genetic defect)
Absence of enzymes required for synthesis or breakdown of gylcogen
Macronutrients and micronutrients
Absorbs through the lymph or blood
What allows for the distribution, use, and storage of nutrients throughout the body ?
Absorption,transport, and metabolism
With proper treatment of PKU
Affected children grow normally and healthy lives
Amount of nutrients absorbed depends on bioavailability?
Amount of nutrient present, competition between nutrients for absorption sites, form in which nutrient is present
The lower part of the stomach is called
Antrum
Phenylketonuria (PKU) (genetic defect)
Are enzymes response for metabolizing essential amino acid phenylalanine is missing
When gylcogen reserves are full, excess energy is stored where ?
As fat via lipogenesis in adipose tissue (fat)
Von ebners glands are located where ?
At the back of the tongue and it secretes lingual lipase
Treatment of GSD is ?
Avoidance of hypoglycemia
Catabolism
Breaking down of larger substances into smaller units
Anabolism
Building up of larger substances from smaller units
If galactosemia is left untreated
Can cause brain and liver damage
pancreatic enzymes
Carbohydrates, proteins, and fats
water and electrolytes
Carey and circulate the products of digestion through the tract and into the tissues
active transport
Carriers partner moves particles across a membrane
lymphatic system
Carries non-water soluble fatty materials, lymph vessels in villi carry fat molecules, route to larger lymph vessels, eventually to bloodstream through thoracic duct
dietary fiber
Contributes bulk to help form feces
What 3 functions does the intramural nerve plexus have ?
Controls muscle tone in wall, regulate rate and intensity of contractions, and coordinate various movements .
disaccharidases
Converts disaccharides into monosaccharides
pancreatic lipase
Converts fat to glycerine and fatty acids
pancreatic amylase
Converts starch to maltose and sucrose
Lactose tolerance
Deficiency of any of the disaccharides in small intestine
All lactose sources must be eliminated from what ?
Diet
4 main steps in preparing food for bodies use:
Digestion, absorption, transport, and metabolism
Bile
Emulsifies fat into smaller pieces to assist fat enzymes
Galactosemia screening and treatment can do what ?
Enable normal life
metabolic processes
Ensure that the body has energy in the form of adesosine triphosphate (ATP)
What does muscle tone (tonic contraction) do ?
Ensures the continuous passage of the food mass and valve control alone the way
Galactosemia (genetic defect)
Enzyme responsible for converting galactose to glucose is missing
Gylcogen storage disease (GSD) depends on what ?
Enzymes missing and tissue affected
Surface villi motions stir and mix chyme which does what ?
Exposes nutrients for absorption
The upper part of the stomach is called
Fundus
Food travels through what system until it is absorbed and delivered to cells or excreted ?
GI System
What at the stomach entrance relaxes, allowing food to enter, then constricts to relation to retain food ?
Gastroesophageal sphincter
Mechanical digestion is also called ?
Gastrointestinal Motility
Chemical Digestion is also called
Gastrointestinal Secretions
They body prefers to use what as its primary source of energy ?
Glucose
Glucose is converted into what ?
Glycogen via glycogenesis, stored in liver or muscles
There are 5 types of GI secretions
Hydrochloric acid and buffer ions, enzymes, mucus, water and electrolytes, and bile
Three types of acid secretions :
Hydrochloric acid, Mucus, & Enzymes
Allergies
Inappropriate immune response , not necessarily a problem with the digestive system
Symptoms of lactose tolerance
Insufficient lactase to break down milk and abdominal cramping and diarrhea . Products containing lactose must be avoided
Metabolism
Is all of the chemical changes in the cell that produce materials for energy, tissue building, and metabolic controls
Peristalsis
Is muscle tone ( tonic contraction) & period muscle contraction
Transport
Is the movement of nutrients through the circulatory system from one area of the body to another
Absorption
Is the taking in of nutrients into cells that line the GI tract
What has to happen for food to become ready to use ?
It has to be changed into simpler substances for absorption and even simpler for constituents that cells can use to sustain life
Protein can be an energy source but :
It is relatively inefficient and results in nitrogen waste
By the time the food mass reaches the lower portion of the stomach what is it ?
It's a semiliquid acid/food mix called chyme
What does the stomach muscles do ?
Knead, mix, store, and propel food mass forward
Pinocytosis
Larger materials are engulfed by a cell
During mechanical digestion what rolls food into a spiral motion, mixing it and exposing it for absorption?
Longitudinal rotation
mucus
Lubricates and protects the GI tract tissues and helps mix the food mass
During metabolism
Macronutrients have been broken down, absorbed into bloodstream or lymphatic system, next nutrients can be converted into energy or stored
At mechanical digestion what begins to break down the food ?
Mastication ( biting & chewing )
What changes must food undergo to be delivered to cell ?
Mechanical and chemical
What two actions makes up the digestive system ?
Mechanical and chemical digestion
Side affects of PKU
Mental retardation and CNS damage
Three absorbing structures
Mucosal folds, villi, & microvilli ( these three structures make the inner intestinal surface area 600 times greater the the outer surface of the intestinal wall
The mucus protects what lining
Mucosal lining
Excess protein/amino acids converted to glucose via gluconeogenesis or converted to fat for storage but they are NOT stored as what ?
Muscle
What are the two general types of movement in the GI wall ?
Muscle tone (tonic contraction) & periodic muscle contraction and relaxation
intramural nerve plexus
Network of nerves in the walls of the intestine that control muscle action and secretions for digestion and absorption. ( extends from the esophagus to the anus)
Intolerance or Allergies aren't what ?
Not genetically inborn errors of metabolism
What does not come ready to use and are packed in foods in a variety of forms ?
Nutrients
simple diffusion
Particles move outward in all directions toward ares of lesser contraction
What types of movements stir chyme ?
Pendulum movements
Enzymes
Pepsinogen is secreted by stomach cells and is activated by HCI to become pepsin. A protein splitting enzyme
What waves pushes food forward during mechanical digestion ?
Peristaltic waves
Three examples of genetic defects are:
Phenylalanine (PKU), galactosemia, and glycogen storage disease
Muscles and nerves work together to do what ?
Produce constant motility ( movement)
Hydrochloric acid and buffer ions
Produces the correct pH necessary for enzyme activity
Which valve slowly releases chyme into the first section of the small intestine ( duodenum)
Pyloric valve
Carboxypeptidase
Removes end amino acids from peptide chains
Salivary glands secrete saliva containing what ?
Salivary amylase or ptyalin
What glands also secrete a mucous material to lubricate and bind food particles, facilitating the swallowing of the food bolus ?
Salivary glands
What from the mucous glands in the esophagus help move food toward the stomach ?
Secretions
mucus
Secretions protect the stomach lining from erosive effect of the acid and also bind and mix food mass and help move it along
What rings chop food mass into lumps ?
Segmentation
Enzymes
Specific digestive proteins for breaking down nutrients
The food enters the upper part of the stomach (fundus) under what control ?
Sphincter control
Trypsin and chymotrypsin
Split large protein molecules into small peptide fragments and eventually into small amino acids ( protein)
Energy that is not need at present is
Stored
Special organ structures and functions accomplish these task through the successive parts of what system ?
The GI System
hydrochloric acid
The hormone gastrin stimulates parietal cells in the stomach lining to secrete acid
Where does mechanical digestion begins ?
The mouth
Digestion
The process by which food is broken down in the GI tract to release nutrients in forms that the body can absorb
Muscles at what base facilitates the swallowing process ?
The tongue
What are periodic muscle contraction and relaxation
They are the rhythmic waves that mix the food mass and movie it forward
facilitate diffusion
Uses a protein channel for carrier-assisted movement of larger particles
Vascular system are :
Veins and arteries, they carry water soluble nutrients, oxygen, other vital substances, transport waste, portal circulation (intestines to liver) first carry nutrients to liver for cell enzymes work
What nutrient does not require digestion and it easily absorbs into the general circulation?
Water
The large intestines main process is to absorb what ?
Water. Small amounts of it remains for the feces
Mitochondria
Where metabolism takes place
What kinds of food must be broken down into smaller substances for absorption and metabolism to meet the body's needs ?
Whole food
metabolism of glucose
Yields less energy than metabolism of fat, but glucose is the body's primary source of energy
Micronutrients are
carbs, protein, fats, water
Two forms of metabolism
catabolism and anabolism
What is chemical and mechanical digestion ?
its when food is broken down into smaller substances and the nutrients are then avaible for biological use