Peds Week 10

Staging is between stages ____ and ____

1, 5

A normal ANC is _____ A decreased ANC is _____

1,000 500

There is only a _______ chance that siblings match their bone marrow

1/4

Give Neupogen sub q or IV for ____ ____ ____ to induce production, can cause severe bone pain in children

10-14 days

The peak age for children with bone tumors is ____ _____ ____

10-18 years

A normal platelet count is ____ If platelets are less than ______ then you have a major risk for hemorrhage

150,000-450,000 20,000

The nurse is administering an intravenous chemotherapeutic agent to a child with leukemia. The child suddenly begins to wheeze and have severe urticaria. Which of the following is the most appropriate nursing action? 1. Recheck rate of drug infusion. 2. Stop drug infusion immediately. 3. Observe child closely for next 10 minutes. 4. Explain to child this is an expected side effect.

2

Genetic mutation before birth and then a clean immune system makes the child very exposed

2 hit theory

The peak age for children with a neuroblastoma

3 years old

Hair will grow back in ____ ____ ____

3-6 months

Give antiemetics _______ before chemo starts

30 minutes

Cancer is the second leading cause of death from disease in children ages ______ ____ ____

5-14

Children with a SCT have no means of fighting an infection for ____ ____ _____ ____

7-10 days

1 in ____ children with downs also develop ______

95, leukemia

Which leukemia has a better survival rate?

ALL

Two types of leukemia

ALL, AML

Medication used to help promote excretion of uric acid in the kidneys

Alopurinol

This med resembles essential metabolic elements needed for cell growth but are altered to prevent DNA or RNA

Antimetabolites

With a lab you would draw a _____ to look at the blood, a complete _____ to look at kidney and liver function, and look at _____ for the kidneys.

CBC, chemistry, urine

They do a lumbar puncture to see if the cancer has metastasized into the _____

CNS

This device makes easy access for chemotherapy, blood sampling, IV fluids, medications, and TPN

CVAD

Bone cancer that is from the space around the bone cells

Ewing

To find donor cells for a SCT you have to match the _____ componenent

HLA

Painful, enlarged lymph nodes is which type of cancer?

Hodgkin lymphoma

Which cancer is more prevalent in advanced, affluent societies?

Leukemia

_______ is given if ANC is less than 500

Neupogen

Bone cancer that is originating directly from the bone cells

Osteosarcoma

DO NOT _____ a Wilm's tumor

Palpate

_____ _____ ______ is better because it has no exit point so it decreases the side effects of radiation

Proton beam radiation

Which cancer is the only one with an inherited gene pattern?

Retinoblastoma

Extent of the disease at time of diagnosis

Staging

____ are chemo drugs that can cause severe damage and need good handling

Vesicants

Those at risk for tumor lysis is a high ____ _____, a large _____, and a sensitivity to ______

WBC count, tumor, chemo

An abdominal mass that does not cross the midline

Wilms tumor

If there is blood return of the CVAD then ______ ____

administer chemo

The first aim of prevention is to prevent ______ _____ by teaching about not smoking, wearing sunscreen, etc.)

adult cancers

You need to _____ treat n/v so the child never experiences it

aggressively

A ______ donation comes from a family member or a donor

allogeneic

Cancer cells don't have organization and they vary in size and shape known as

anaplasia

Normal cells will only grow on an attached, firm surface but cancer cells can grow on virtually any surface known as _____ _____

anchorage independence

Cancer cells provide their own blood supply to support their growth known as _____

angiogensis

To assess a CVAD _____ for blood return

aspirate

A ______ donation comes from the patient themself

autologous

Cancer cells have _____ meaning they are independent from normal cellular controls

autonomy

Stem cell transplants have 3 reasons. The first reason for a SCT is that the ____ ____ is not functioning, may be caused by aplastic anemia

bone marrow

Most common solid tumor in pediatrics

brain

Long term effects of radiation are most damaging to children with ____ _____

brain tumors

What is the second leading cause of death from disease in children

cancer

If a thrombolytic doesn't work to get blood return, then order a ____ _____ to check placement

chest x-ray

Biological characteristics of the tumor like the origin and cell analysis

classification

Surgery can be ____ or ____

curative, palliative

An _____ CVAD has tubes coming out of the body and is for more of a short term solution

external

Don't give the child's _____ _____ because you don't want them to develop an _______ later

favorite food, aversion

A hallmark of tumor lysis syndrome is ___ _____ from crystallization of uric acid

flank pain

Never ____ _____a port!

force flush

With chemo it is imperative that you have a ____ _____ IV

free flowing

In younger children with a brain tumor, you would see an increase in _____ _____

head size

HLA stands for

human leukocyte antigen

The BEST prophylaxis treatment for tumor lysis syndrome is

hydration

Leukemia is the unrestricted proliferation of ______ _____

immature WBC

Cancer cells are _____ meaning they never die

immortal

The biggest priority for children receiving a SCT is preventing

infection

An _____ CVAD has a port access by going through the skin and is for long term, you can go swimming!

internal

All leukemia patients receive an _____ ______ as prophylaxis for CNS metastasis

intrathecal injection

A wilms tumor is a tumor in the ____

kidneys

Second reason for a SCT is as a treatment for _____

leukemia

Chemo kills ____ and _____ cells

malignant, nonmalignant

Chemo drugs are classified according to their ____ ____ ____

mechanism of action

In older children with a brain tumor, they would have _____ _____

morning nausea/vomiting

A firm, non tender, irregular abdominal mass that crosses midline would be a ___

neuroblastoma

Four electrolytes found with tumor lysis syndrome

phosphate, calcium, potassium, sodium

Which vaccines should you not give when the child has cancer?

polio, chicken pox, MMR

If there is no blood return, then ________ patient first because it is least invasive

reposition

Radiation is used to ______ the tumor and also prepare for a _____ _____ ____

shrink, stem cell transplant

The second aim of prevention is to recognize the early ____ and _____ of cancer

signs, symptoms

The third reason for SCT is that chemo was used to treat a ____ _____ but it also killed the bone marrow

solid turmo

If there is still no blood return after repositioning, then get an order for a ________

thrombolytic agent

Rapid release of intracellular contents from cancer cells to the blood stream is known as ___

tumor lysis syndrome