Quiz 9

What does the term gene expression mean? Question 19 options: A. The gene makes RNA which may be decoded to make a protein. B. The gene is tuned off. C. The gene contains many exons.

A. the gene makes RNA which may be decoded to make a protein

Post-translational modifications of proteins can affect which of the following? Question 13 options: a. protein function b. transcriptional regulation - c. chromatin modification d. all of the above -

a. protein function

What are epigenetic modifications? Question 20 options: a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequence

a. the addition of reversible changes to histone proteins and DNA

What will result from the binding of a transcription factor to an enhancer region? Question 6 options: a. decreased transcription of an adjacent gene b. increased transcription of a distant gene c. alteration of the translation of an adjacent gene d. initiation of the recruitment of RNA polymerase

b. increased transcription of a distant gene

Post-translational control refers to: Question 12 options: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translation

b. regulation of gene expression after translation

If glucose is absent, but so is lactose, the�lac�operon will be ________. Question 10 options: a. activated b. repressed c. activated, but only partially d. mutated

b. repressed

A(n) __________ operon uses a protein bound to the promoter region of a gene to keep the gene repressed or silent. Question 7 options: activator inducible repressible negative

b. repressible

Which of the following types of chromatin is associated with actively expressed genes? Question 14 options: A. heterochromatin B. homochromatin C. Euchromatin

c. Euchromatin

This is a segment of DNA that can be thousands of nucleotides away from a gene yet influence the transcription of that gene. Question 11 options: a. terminator b. promoter c. enhancer

c. enhancer

Cancer causing genes are called ________. Question 1 options: a. transformation genes b. tumor suppressor genes c. oncogenes d. mutated genes

c. oncogenes

Targeted therapies are used in patients with a set gene expression pattern. A targeted therapy that prevents the activation of the estrogen receptor in breast cancer would be beneficial to which type of patient? Question 15 options: a. patients who express the EGFR receptor in normal cells b. patients with a mutation that inactivates the estrogen receptor c. patients with lots of the estrogen receptor expressed in their tumor d. patients that have no estrogen receptor expressed in their tumor

c. patients with lots of the estrogen receptor expressed in their tumor

The binding of ________ is required for transcription to start. Question 16 options: a. a protein b. DNA polymerase c. RNA polymerase d. a transcription factor

d. a transcription factor

Which of the following are involved in post-transcriptional control? Question 2 options: a. control of RNA splicing b. control of RNA shuttling c. control of RNA stability d. all of the above

d. all of the above

Which of the following are true of epigenetic changes? Question 3 options: a. allow DNA to be transcribed b. move histones to open or close a chromosomal region c. are temporary d. all of the above

d. all of the above

Prokaryotic cells lack a nucleus. Therefore, the genes in prokaryotic cells are: Question 8 options: a. all expressed, all of the time b. transcribed and translated almost simultaneously c. transcriptionally controlled because translation begins before transcription ends d. b and c are both true

d. b and c are both true

Binding of an RNA binding protein will ________ the stability of the RNA molecule. Question 9 options: a. increase b. decrease c. neither increase nor decrease d. either increase or decrease

d. either increase or decrease

Control of gene expression in eukaryotic cells occurs at which level(s)? Question 4 options: a. only the transcriptional level b. epigenetic and transcriptional levels c. epigenetic, transcriptional, and translational levels d. epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels

d. epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels

Heritable changes that do not invovle changes in the DNA sequence are called: Question 17 options: epigenetic post-transcriptional mutations

epigenetic

Which of the following is an oncogene that causes cancer in many cell that become cancerous? Question 5 options: a. trp b. lac c. myc

myc

A protein that binds to the DNA at the promoter or enhancer region and that influences transcription of a gene is known as a(n): Question 18 options: transcription factor operon promoter

transcription factor