Upper GI System Drugs

A client has been prescribed rabeprazole (Aciphex). It will be important for the nurse to assess the client's drug history to determine if the client is taking which drug

Digoxin

A critical care nurse is preparing to administer an intragastric drip of an antacid to a client through a nasogastric tube. How should the nurse most accurately titrate the dose and frequency?

By aspirating stomach contents and measuring the pH

antacids are alkaline substances primarily used to directly neutralize gastric acid in the stomach to prevent/treat PUD, GERD, heartburn, and GI bleed. In the treatment of what medical diagnosis might aluminum-based antacids be used? Select all that apply.

Chronis renal failure Hyperphosphatemia

Which medication reduces the secretion of gastric acid by inhibition of the hydrogen-potassium adenosine triphosphate (ATPase) enzyme system of the gastric parietal cells? Select all that apply.

Esomeprazole, Lansoprazole

Which herbal products have been used as a homeopathic remedy for GI problems, including motion sickness, nausea, vomiting, and digestion? (Choose one)

Ginger

The client will receive cimetidine 800 mg PO at bedtime. Prior to administration, the nurse should inform the client that common side effects related to this medication include:

headache

A nurse is teaching a client about omeprazole, which has been prescribed as part of a regimen to treat an H. pylori infection. What statement, made by the client, suggests that the client understands proper use of the drug?

"I need to swallow the drug whole."

What is the benefit of adding proton pump inhibitors (PPIs) to the treatment regime treating an H. pylori bacterial infection?

decreases production of gastric secretions

A client presents to the walk-in clinic reporting vomiting and burning in the mid-epigastria. The nurse suspects peptic ulcer disease and knows that to confirm peptic ulcer disease, the provider is likely to order a diagnostic test to detect the possible presence of what?

Infection with Helicobacter pylori

A client is diagnosed with peptic ulcer disease complicated by H. pylori. What is the rationale for adding bismuth to the client's medication regimen?

Provides antibacterial effects

The nurse is caring for a 27-year-old female client who has just been prescribed misoprostol. What is a priority teaching point for this client?

You will need to use a barrier-type contraceptive

The nurse is caring for a client who is prescribed esomeprazole. The client informs the nurse that they are also taking sucralfate. The nurse would anticipate which effect as a possibility when these two drugs are administered?

decreased absorption of the esomeprazole

A male client tells the nurse that he takes antacid tablets several times each day. Knowing that the brand of antacid he uses contains calcium carbonate, the nurse cautions the client that overuse could place him at risk for:

metabolic alkalosis

Which client is at risk for the development of an acute ulcer? select all that apply.

A client on a mechanical ventilator for 5 days A client with 2nd degree burns over 50% of the body A client who experienced a stroke A client who is diagnosed with jaundice

Which client would be most likely to benefit from treatment with ondansetron (Zofran)?

A woman who is receiving chemotherapy for the treatment of colon cancer

A client has been prescribed chlorpromazine hydrochloride for nausea. What assessment should the nurse perform before the drug is administered to the client?

Assess signs of fluid and electrolyte imbalances

A client has presented to the emergency department with a 48-hour history of spasticity, malaise, and agitation. Arterial blood gas testing reveals that the client has metabolic alkalosis. What is the most appropriate action by the nurse?

Assess the client's use of sodium bicarbonate and other antacids.

An antacid has been added to the treatment regimen for a client on multiple medications. When is the best time for the nurse to administer the antacid?

At bedtime

The nurse should be aware that ranitidine achieves a therapeutic effect by which means?

Inhibiting the secretion of gastric acid

A client is diagnosed with peptic ulcer due to H. pylori. The nurse would anticipate administering which agent in conjunction with an antibiotic?

Omeprazole

A client with peptic ulcer disease is experiencing fewer symptoms because of suppression of hydrochloric acid secretion into the lumen of the stomach. What category of medication is this client most likely receiving?

Proton pump inhibitor

A client with a history of peptic ulcer disease has responded well to treatment with a histamine-2 antagonist. What effect will this drug have?

Reduce the quantity of hydrochloric acid secreted.

A client is prescribed cimetidine for the treatment of a peptic ulcer disease and gastric reflux. The dosage of this drug should be reduced if the client has:

Renal disease

The client has a magnesium-based antacid prescribed for administration before meals. The nurse knows to withhold the medication if the client exhibits what?

Renal dysfunction

A nurse is planning care for a 59-year-old woman who is on ranitidine therapy. The nurse is concerned for the client's safety. What would be an appropriate nursing diagnosis?

Risk for Injury related to drug-induced somnolence, dizziness, confusion, or hallucinations

A client diagnosed with an H. pylori-associated ulcer has been prescribed treatment that includes two antimicrobials. What does the nurse identify as the reason for using multiple antimicrobials?

Two antimicrobials help prevent the emergence of drug-resistant H. pylori organisms

A client, with recent abdominal pain and a 40-pack per year smoking history, is prescribed a treatment regimen for a diagnosis of duodenal ulcer. What important teaching would the nurse include in relation to treatment?

smoking effects on the healing of ulcers

A nurse is teaching a client about prescribed lansoprazole. The nurse instructs the client to take the drug at which time?

1 hour before eating

A client is prescribed a proton pump inhibitor to treat erosive gastritis. How soon will the client's symptoms be resolved?

1 to 2 weeks

A client has been prescribed 200 micrograms of misoprostol to be taken 4 times a day orally for the prevention of gastric ulcers. The drug is available in 100 microgram tablets. How many tablets should the nurse administer to the client each time?

2 tabs

A client with ulcers has asked the nurse if it would be acceptable to take bismuth subsalicylate. Before recommending an over-the-counter (OTC) formulation of bismuth subsalicylate, the nurse should conduct which client assessment?

Allergy status

The nurse is caring for four clients. Which client would benefit most from misoprostol, a synthetic prostaglandin E analog?

An 83-year-old male with rheumatoid arthritis

The nurse should warn a client taking aluminum- and calcium-containing antacids about which adverse effects?

Constipation

Which adverse reaction of proton pump inhibitors is specific to menopausal women with osteoporosis?

Increased fracture risk

A client arrives at the walk-in clinic reporting vomiting and a burning sensation in the mid-epigastric region. The nurse suspects that the client has peptic ulcer disease. Which is a potential cause of peptic ulcer disease?

Infection with H. Pylori

A client has been prescribed rabeprazole (Aciphex). It will be important for the nurse to assess the client's drug history to determine if the client is taking which drug?

digoxin

An older adult client has been on long-term proton pump inhibitor (PPI) therapy. The nurse practitioner should focus on what assessment related to adverse effects?

bone density

While reviewing the medication history of a client's newly prescribed omeprazole, the nurse sees that the client is also taking warfarin. What potential interaction should the nurse account for when developing the plan of care for this client?

hemorrhage

What is the most likely reason esomeprazole (Nexium) has been prescribed for a client who has a diagnosis of H. Pylori and is taking antiplatelet drugs?

prevention of bleeding

The nurse administers ranitidine cautiously to clients with evidence of what condition?

renal disease

How does histamine release contribute to ulcer formation?

stimulates gastric acid secretion

The nurse is caring for a client requiring digestive enzyme replacement therapy. What is the appropriate nursing diagnosis for this client?

Risk for imbalanced nutrition

Client teaching should include what instruction about antacids?

Take antacid 1 hour before other medications.

The nurse is caring for a client who has recently been prescribed misoprostol. What change in the client's health status should the nurse communicate most promptly to the care provider?

The client believes that she may be pregnant.

Administering an antacid to a client taking which medications will decrease the absorption of the medication and result in a decreased drug effect?

digoxin