Vancomycin-Resistant Enterococci (VRE)
Treatments
-Antibiotic Sensitivity Testing -Resistant to Many Antibiotics (4 From Notes) - Linezolid (Protein Synthesis Inhibitor) -Telavancin (Synthetic Vancomycin/Glycopeptide)
Problem
-First Isolated in France 1986 (America 1989) -Avoparcin Used In Animal Feeds in Europe -HUGE Problem -Clinical Samples 100% -Carriers 12%
VRE
-Gram + Cocci -Healthcare Associated Infections (NOSOCOMIAL) -Normal Flora (Colon, Female Genital Tract, Skin)
At Risk on Infection
-Long Term Antibiotic Use -Hospitalization (HAIs) -Weakened Immune System -Surgical Procedures -Medical Devices -Carriers of VRE (Exposure-Normal Flora)
Solution
Banned Use of Avoparcin in Animal Feed -Reduced Clinical to 25% -Reduced Carriers to 3% -Remove the Resistance wth Change of Behavior or How Antibiotic is Used
Possible Infections
UTIs Bacteremia Endocarditis