Vancomycin-Resistant Enterococci (VRE)

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Treatments

-Antibiotic Sensitivity Testing -Resistant to Many Antibiotics (4 From Notes) - Linezolid (Protein Synthesis Inhibitor) -Telavancin (Synthetic Vancomycin/Glycopeptide)

Problem

-First Isolated in France 1986 (America 1989) -Avoparcin Used In Animal Feeds in Europe -HUGE Problem -Clinical Samples 100% -Carriers 12%

VRE

-Gram + Cocci -Healthcare Associated Infections (NOSOCOMIAL) -Normal Flora (Colon, Female Genital Tract, Skin)

At Risk on Infection

-Long Term Antibiotic Use -Hospitalization (HAIs) -Weakened Immune System -Surgical Procedures -Medical Devices -Carriers of VRE (Exposure-Normal Flora)

Solution

Banned Use of Avoparcin in Animal Feed -Reduced Clinical to 25% -Reduced Carriers to 3% -Remove the Resistance wth Change of Behavior or How Antibiotic is Used

Possible Infections

UTIs Bacteremia Endocarditis

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