4.19 The extracellular matrix of animal cells function in support and regulation

extracellular matrix (ECM)

A substance in which the cells of an animal tissus are enbedded; consists of protein and polysaccharides.

integrins

A transmembrane protein that interconnects the extracellular matrx and the cytoskeleton.

extracellular matrix (ECM)

Animal cells produce an ________ _______. This elaborate layer helps hold cells together in tissues and protects and supports the plasma membrane.

signals

Integrins have the function of integration: They transmit ________ between the ECM and the cytoskeleton.

integrins integrins

The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called ________. ________ span the membrane, attaching on the other side to proteins connected to microfilaments of the cytoskeleton.

glycoproteins, proteins

The main components of the ECM are ________, _______ bonded with carbohydrates.

collagen collagen

The most abundant glycoprotein is ________, which forms strong fibers outside the cell. In fact _______accounts for about 40% of the protein in your body.