Blood Cells (pictures)

Promonocyte

12-18um. Nucleus is slightly indented/folded. Chromatin pattern is delicate. At least one nucleolus is present. Blue cytoplasm with scattered azule granules

Monocyte

15-20um. Nucleus can be oval, round, kidney shaped, but mostly horseshoe shaped or folded on self. Chromatin is loose and stringy. Blue-gray cytoplasm and azure granules (ground-glass appearance). Psuedopods or blebs often seen

Segmented neutrophil

3-4 nuclear lobes attached by threadlike filaments. Secretory granules present

Megakaryocyte

30-50um. Multilobulated nucleus. Abundant granular cytoplasm

Basophil

Bean shaped nucleus

Eosinophils

Biloped nucleus. Refractile, orange-red secondary granules in cytoplasm

Macrophages

Can be as large as 40-50um. Usually oval nucleus with netlike chromatin pattern. Cytoplasm is pale, frequently vacuolated, and often filled with debris of phagocytized cells in organisms

Neutrophil promyelocyte

Chromatin becomes compact, nucleus is eccentric, primary granules present

Karyolysis

Chromatin dissolution due to action of DNAases and RNAases which leads to necrosis

Neutrophil myelocyte

Chromatin is even more compact into a round nucleus. Last stage of capable mitosis. Secondary granules are formed

Neutrophil metamyelocytes

Chromatin is more compact into a kidney bean shape. Secondary and tertiary granules are formed

Hemochromatosis

Condition when stained with Prussian blue reaction gives the particles a blue hue

Basophil

Contains lobulated nucleus obscured by its granules. Chromatin is clumped. Colorless cytoplasm and large blue-black granules

Plasma cell

Cytoplasm is basophilic because of abundance of ribosomes

Neutrophil myeloblast (myelocytic series)

Earliest recognizable cell of this series

Lipofuscin

Finely granular yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion. It is considered to be one of the aging or "wear-and-tear" pigments, found in the liver, kidney, heart muscle, retina, adrenals, nerve cells, and ganglion cells

Eosinophil

Has only one nucleus divided into 2 lobes at opposite sides of the cytoplasm

Immature basophil

Has round, lobulated nuclei with only slightly condensed chromatin. Cytoplasm is blue and contains large blue-black secondary granules which water soluble and may be dissolved of the blood film is washed too much during the staining process

Hemosidirin

Iron-storage complex. Can be identified with "Perls prussian blue" stain. Commonly found in macrophages and is especially abundant in situations following hemorrhage, suggesting that its formation may be related to phagocytosis of red blood cells and hemoglobin

Eosinophil myelocytes

Large, pale, reddish-orange secondary granules, along with azure granules in blue cytoplasm

Band

Nucleus shows compact chromatin that is shaped into a horseshoe. Tertiary and secretory granules are formed

Karyorrhexis

Pyknotic nuclei membrane ruptures and nucleus undergoes fragmentation leading to necrosis

Eosinophil metamyelocytes

Secondary granules increase in number and a third type of granule is generated called: secretory granule (vesicle)

Reticulocyte

Small amount of residual ribosomal RNA is present which appear as a mesh of small blue strands

Hemochromatosis (hereditary)

The disease characterized by an accumulation of an iron-rich brown pigment, in liver and Kupffer cells

Pyknosis

When the DNA condenses into a shrunken basophilic mass

Anthracosis

Where inhaled coal dust progressively builds up in the lungs and cannot be removed by the body which leads to inflammation, fibrosis, and necrosis