BME3 Exam Study
glucose oxidase was isolated from
fungus
george walden was the engineer at the Eli Lilly in charge of insulin production and purification. George Walden's major contribution was that:
he invented isoelectric precipitation
the Ames Reflective Meter was one of the first
home based blood glucose meters
james collip discovered that if he injected too much insulin into a rabbit it developed convulsions. This effect is known as
hypoglycemia
diabetes was first described
independently by many different cultures
the fragment of preproinsulin called c-peptide
is essential, people will die within months without it
engineered E. coli bacteria containing recombinant DNA is not dangerous to humans because
it is incapable of surviving outside well controlled laboratory environments
congress passed the animal welfare act of 1966 after an uproar caused by the publication of an article about dog dealers in what magazine?
life
fred banting grew up
on a farm
immediately after his one year of surgical residence at toronto's hospital for sick children, fred banting
opened his own practice to see patients
arnold beckman invented and sold one of the first integrated
pH meters
during the summer of 1921, Fred Banting performed experiments on dogs. In one group of dogs, he tried to cause the dogs to develop diabetes by removing an organ. Which organ did he remove?
pancreas
from the 1920s through the 1960s, insulin used by patients with diabetes came from which sources
pigs and cows
fred banting developed his idea on how to treat diabetes while he was
preparing a lecture for medical students
the label of a prescription drug
summarizes all the scientific information known about the drug
the quantity known as pH measures
the concentration of hydrogen ions in a solution
james collip, at the University of Toronto, developed a method to isolate insulin based upon
the solubility of insulin in alcohol/water mixtures
banting's method of isolating insulin involved a surgical procedure to tie off ducts in the pancreas, waiting several weeks, then removing the pancreas.
this method was used to produce insulin for just a few times
patients enrolled in the Diabetes Control and Complications Trial were randomly assigned to be part of the tight control group or the standard group.
true
an insulin molecule in circulating in your bloodstream consists of
two chains of amino acids linked together by disulfide bonds
fred banting performed his experiments on dogs at
uni of toronto
today, most insulin in produced in a large factory by which types of organisms
yeast or bacteria
the University of Toronto licensed a patent on the production of insulin to Eli Lilly. The agreement allowed Eli Lilly to manufacture and sell insulin. In return, Eli Lilly would give the University of Toronto
5% of Eli Lily's net sales from the insulin
off label prescribing is when
a physician prescribes a drug to treat a condition that was NOT approved by the FDA
axel ullrich was the first person to insert the human insulin gene into a bacteria, or clone the insulin gene. He obtained the human insulin gene that he cloned from
a woman's insulinoma tumor that was surgically removed
fred banting entered medical school
after dropping out of college
severe symptoms of hypoglycemia could be confused with
alcoholic intoxication
a closed loop system for insulin delivery contains
an insulin pump and a continuous blood glucose meter
the birth control drug Nexplanon is usually implanted under the skin of a woman's
arm
a complete lack of vitamin A in a person's diet can lead to
blindness
in 1921, picric acid was used as a
both a common laboratory reagent and an explosive for artillery shells
In 1920 the company Eli Lilly was known for manufacturing
capsules for drugs
the Diabetes Control and Complications Trial monitored this complication that many diabetes patients suffer
damage to the retina's blood vessels
afrezza and exubera are two different insulin delivery systems. These two systems both
deliver insulin through the lungs
which of the following was not a frequent complication from diabetes before the Diabetes Control and Complications Trial
dementia
x-ray crystallography can be used to
determine the 3 dimensional structure of a protein
the order of amino acids in a protein produced by your body is
determined by your DNA
the birth control drug Nexplanon is implanted under the skin. Nexplanon is an example of ________ applied to birth control
drug delivery
around 1920, the amount of glucose in blood could be measured by an electronic meter.
false!
hypoglycemia can be alleviated by injecting insulin.
false!
when insulin is injected under the skin it has an immediate effect, lowering blood sugar levels within a few seconds.
false!
one of the most common problems people who have lived with diabetes for decades have is with their
feet
