Chapter 11 Epidemiology
Most sexually transmitted viruses are?
Latent infections
Sometimes, the term virulence is used to express the measure or degree of ________.
pathogenicity
Indirect contact via airborne droplet modes of transmission
sneezing and coughing, airborne enters through respiratory system, droplet through mouth and nose
A disease that is occurring in epidemic proportions in many countries simultaneously, AROUND the world
Pandemic
Never had the disease, but can still spread it
Passive carries
The steps or mechanisms involved in the DEVELOPMENT of a disease
Pathogenesis
The ability to cause disease
Pathogenicity
Number of cases of a disease existing in a given population during a specific time period, ex during year 2009
Period prevalence
Two types of prevalence
Period prevalence and point prevalence
Number of cases of a disease existing in a given population at a particular moment in time, ex. right now.
Point prevalence
Steps in the Pathogenesis of infectious diseases.
1. Enter the body 2. Attach 3. Multiply 4. Spread 5. Evasion of host 6. Damage
An infectious disease than can be transmitted from one person to another
Communicable disease
A communicable disease that is EASILY transmitted from person-to-person. Ex. Ebola
Contagious disease
Why do we need to know modes of transmission?
Decides how much protection we need
What transmission is easiest to control?
Direct transmission
Words containing the prefix "path" or "patho-" pertain to ?
Disease
Who is the father of Epidemiology?
Dr. John Snow
Pathogens that MUST live WITHIN host cells in order to survive and multiply are referred to as ?
Obligate intracellular pathogens
One infectious disease may commonly follow another
Primary Versus Secondary Infections
Sources of microorganism causing infectious diseases are known as?
Reservoirs of infection or reservoirs
Four periods or Phases in the course of an infectious disease. -Patient feels I am coming down with something, before drama begins
Second stage. Prodromal period
Which is more serious, primary or secondary infections?
Secondary
What virulences can cause sickness?
Shigella cells, Salmonella cells
One that occurs only occasionally within the population of a particular geographic area; ex. Tetanus
Sporadic disease
When the infection spreads throughout the body it is said to have become a _______ or generalized infection; ex. miliary tuberculosis caused by mycobacterium tuberculosis
Systemic infections
Best case scenario to break the chain of infection is?
Take away the pathogen, and if you can not take away the pathogen, take away the environment
What do we call antibacterial factors?
bacteriocins
The easiest modes of transmission is?
direct skin-to-skin contact
Four periods or Phases in the course of an infectious disease. -The date between arrival pathogen and onset symptom
first stage. Incubation period time
Most flue can be transmitted during?
incubatory period
A person can be _____ with a pathogen, but no have an ________
infected, infectious disease
Four periods or Phases in the course of an infectious disease. - Experience symptoms of disease
third stage. Period of illness
Transit white recovering
Convalescent carriers
Factors of infect. disease to occur.
-Factors pertaining to the PATHOGEN, HOST, ENVIRONMENT
Factors pertaining to the environment
-Physical factors -climate, season -geographic location - availability of appropriate reservoirs -sanitary and housing conditions -availability of potable water
Factors pertaining to the Host
-health status -nutritional status -hygiene -age -travel -lifestyle -stress, etc
Factors pertaining to the pathogen
-virulence of pathogen (strong/weak) -Mode of enter (air, water) -Number of organisms that can enter body
Completely recovered but have pathogen
Active carriers (completely sick)
Disease is one that has a RAPID ONSET, and is usually followed by a relatively repaid recovery
Acute
What are some nonliving reservoirs?
Air, soil, dust, contaminated water and foods, and fomites
What do we call infections of the pathogen by rabies and lyme?
Arthropod
Most common chronic disease?
Back pain
What bacteria has pathogenicity?
Bad bacteria
Living reservoir- Human
Carrier base Disease
Disease has a SLOW ONSET and lasts a long time
Chronic
What is an example of latent infections?
Cold Sore
One that is always present within the population of a particular geographic area disease never dies out completely; Ex. Common Cold
Endemic disease
Defined as a GREATER than usual number of cases of a disease in a particular region, usually within a short period of time; ex. the legionnaire's disease epidemic of 1976
Epidemic disease
Loosely defined as the study of disease
Epidemiology
Pathogens that are capable of BOTH an INTRACELLULAR AND EXTRACELLULAR existence.
Facultative Intracellular Pathogens
Opposite of obligate is?
Facultative intracellular pathogens
Inanimate (nonliving) objects capable of transmitting pathogens (bedding, towels, eaten and drinking utensils hospital equipment. ONLY health centers
Fomites
Four periods or Phases in the course of an infectious disease. -Patient recovers
Fourth stage. Convalescent period
Number of new cases in specific population in a specific period
Incidence
Four periods or Phases in the course of an infectious disease.
Incubation period time, prodromal period, period of illness, convalescent period
Capable of transmitting during incubation period, spread during initial time
Incubatory carriers
Colonization by a pathogen, the pathogen may or may not go on to cause disease
Infection
A disease caused by a microbe
Infectious disease
What is an example of Pandemic?
Influenza, HIV/AIDS, Tuberculosis, Malaria
Are infectious diseases that of from being symptomatic to asymptomatic and than later go back to being symptomatic.
Latent Infections
Reservoirs are?
Living and nonliving
Once an infectious process is initiated, the disease may REMAIN ______ or it may spread; ex. pimples, boils, abscesses
Localized Infection
Numer of new cases of a during specific time period per a specific population, ex. usually per 1,000/10,000/100,000 (How sick you're going to be)
Morbidity
Ratio of number of people who DIED of a particular disease during a specific time period per a specific population
Mortality
There are symptomatic and asymptomatic diseases.
True
Living reservoirs- Arthropods
Vectors base disease
Plasmodium (which causes malaria) intraerythrocytic pathogens; they live ________.
Within Red blood cells, inside the cell
Diseases from animal sources
Zoonotic disease
Living reservoir- Animals
Zoonotic diseases or zononeses base disease