Clinical Medicine IV - Lecture 11 - Disorders of Hemostasis
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some key points in disorders of hemostasis 1) disorder of platelets or von willebrand factor causes what symptom? 2) disorder of clotting factors - cause what specific symptoms? 3) screening tests for bleeding disorders 4) how will a mixing study look if it is a clotting factor deficiency? inhibitor? 5) peripheral smear in DIC, TTP, HUS will show?
1) mucosal type bleeding 2) spontaneous hemarthroses, muscle hematomas 3) platelet count, PT, aPTT, TT 4) clotting factor deficiency - prolong aPTT will correct inhibitor - prolonged aPTT will not correct 5) schistocytes + thrombocytopenia on peripheral smear
