Difference between Class I and Class II MHC proteins

Where are Class II MHC proteins found?

Typically found only on the surfaces of APCs

Class I (endogenous antigens) can be ______ or ________

self or nonself

Specific cell type where Class II MHC proteins are found?

APC cells

Specific cell type where Class I MHC proteins are found?

All nucleated cells

What are the exogenous antigens found in Class II MHC proteins?

Antigens from outside the cell that have been engulfed by the cell that displays them

Which class is more common?

Class I MHC protein

Where are Class I MHC proteins found?

Found on virtually all body cells - except red blood cells

What are the endogenous antigens found on class I MHC proteins?

Fragments of proteins synthesized inside the cell

What does MHC stand for?

Major Histocompatibility Complex

Class II (exogenous antigens) are ALWAYS ______

Non-self, NEVER self

Specific example of cells that are class II MHC?

dendritic cells, macrophages and B cells

All antigens displayed on class I MHC proteins are _____ ________

endogenous antigens

The antigens for Class II MHC proteins are _____ _______-

exogenous antigens