FUNGI CASE STUDY 2

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Based on the signs and symptoms described so far, which disease(s) from this differential diagnosis chart might explain Jade's condition? To be marked correct, you'll need to select all applicable diseases, as there may be more than one correct answer. (NCLEX-HESI-TEAS Style)

Histoplasmosis Tuberculosis

Itraconazole is in the azole family of antifungal drugs. What is its mechanism of action?

It inhibits ergosterol production.

Jade's chest X-ray image came back from radiology and is shown below. For comparison, a normal chest X-ray image is also shown. What can be concluded from these data? (NCLEX-HESI-TEAS style)

Jade has a lung infection.

Jade's temperature at the hospital was 100.0°F. What treatment should be administered? (NCLEX-HESI-TEAS style)

Low-grade fevers don't necessitate treatment; if the patient is still able to rest, let it run its course.

The results of the differential blood count are shown here. What is your interpretation of these data? (NCLEX-HESI-TEAS style)

No new information can be extracted about Jade's condition.

Why does Jade have antibodies to two different morphological forms of Histoplasma?

She was exposed to both the mycelial and the yeast forms of the organism at some point in her infection.

Upon Jade's diagnosis, some of the other people on Jade's trip were contacted and given a skin test that detects Histoplasma capsulatum exposure. Although several people in the traveling cohort tested positive for an exposure, no one aside from Jane had any signs or symptoms of the disease. Strangely, one of these people, a graduate student from Ohio, never even went into the caves, yet still had a positive skin test result. How can this be explained? (NCLEX-HESI-TEAS Style)

The fungus is endemic in several places, but it rarely causes disease.

What tests/procedures should the healthcare staff run on Jade? To be marked correct, you'll need to select all applicable tests/procedures, as there may be more than one correct answer. (NCLEX-HESI-TEAS Style)

A physical exam A PPD (skin test for tuberculosis) A complete blood count (CBC)


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