human growth hormone
how many amino acids are there?
191
what professional sports are currently testing for hGH?
NFL and MLB
hGH is an ______ which is ______ in nature.
amino acid; anabolic
how does GH affect exercisers?
anabolic steroids cause hypertrophy; hGH cause hyperplasia; hGH decreases body fat
where is hGH secreted from?
anterior pituitary gland
hGH is the most sought after drug among ______.
athletes
what is somatotrop adenomas?
benign tumors that may grow in and around the brain (headaches, blurred vision, etc.)
what test can hGH be detected through?
blood draws
what were the original intended uses for hGH?
children who suffered from growth disorders and adults who were not endogenously producing enough GH
how does exercise affect the action of hGH?
exercise stimulates endogenous hGH output in both men and women; aerobically and anaerobically
how does hGH cause hyperplasia?
increased amounts of RNA lead to increased protein synthesis; GH effects on muscle persist and do not wear off like the effects of anabolic steroids (endogenous levels that are elevated cause acromegaly)
what are complications that arise from needle sharing risks?
infection and skin scarring
can dwarfism be corrected by supplementary hGH?
yes
hGH is a ______ hormone.
peptide
what is pituitary gigantism?
rare, but results from a GH secreting tumor in children
what does hGH stimulate?
regeneration and growth and cell reproduction
what happens if hGH is abused?
somatotrop adenomas; acromegaly; pituitary gigantism
what is human growth hormone known as?
somatotropin or somatropin
what is acromegaly?
thickened jawbone, forehead, fingers and toes
hGH is initially undetectable through what standard test?
urine screen drug tests
is hGH ergogenic in those that are not GH deficient?
no
what is the NCAA and USOC status on hGH?
both have banned hGH
is affect of hGH action related to the inrensity of activity?
hGH is attenuated by age and level of activity even though GH levels do spike (post exercise) in elderly men and women who use contraceptives
exogenous GH administration to those who are deficient has been associated with what?
improvement in exercise performance (increased muscle mass and muscle strength)
why do athletes use hGH?
increases calcium retention, and strengthens and increases the mineralization of bone; increases muscle mass through sarcomere hyperplasia; promotes lipolysis; increases protein synthesis; stimulates the growth of all internal organs excluding the brain; plays a role in homeostasis; reduces liver uptake of glucose
what reasons that athletes take hGH have actually been proven?
increases muscle mass through sarcomere hyperplasia; increases protein synthesis
what are the potential complications of hGH?
long term effects of administration are not reversible (acromegaly); needle sharing risk; bad batches of synthetic hGH
does GH supplementation improve the muscular strength on non deficient endogenous GH power lifters?
no