Human Growth Hormone

Under the influence of HGH fats may be used in preference to what

-Carbohydrates and proteins for energy

Production of HGH may be stimulate during what

-Starvation -Fasting

HGH does NOT *directly* affect what

-bone -cartilage growth

HGH is critical for what

1. Tissue repair 2. Muscle growth 3. Brain function 4. Bone strength 5. Metabolic balance

What is the best way to determine the adequacy of HGH in the body

By checking IGF levels

Where does IGF1 form and as a result of what?

In the liver and possibly the kidneys as a result of stimulation by HGH

What was the original method used to treat children with growth deficiencies

Injection of natural HGH

It is difficult to measure HGH levels why

It is rapidly used up and absorbed by the liver. It does not last long in the blood stream

What promotes the basis for most over the counter HGH supplements

People claiming that ingestion of certain amino acids will stimulate the production and the release of HGH

What are symptoms of acromegaly

1. Distorted bone and skull development 2. Kyphosis 3.Enlargement of tongue, Kidneys, and Liver

Insulin like Growth Factor 1 is also called what

Somatomedin C

Human Growth Hormone is also called what

Somatotropin

Secretion of HGH responds to what

changes in protein and carbohydrate levels

Blood concentration of HGH varies how

during the day and can change VERY rapidly

Where does IGF1 stay?

in the blood stream for an extended period of time

Chondroitin sulfate is necessary for what

the growth of cartilage and bone -Because HGH promotes the formation of IGF1 it *INDIRECTLY* promotes bone growth

What are the results of HGH deficiency?

1. Inadequate cell maintenance and repair 2. Inadequate growth 3. Dwarfism 4. Protein breakdown- bc it usually inhibits its breakdown 5. Reduced energy levels

What are the results of an excess of HGH

1. Joint pain 2. Fluid retention 3. Hypertension 4. Carpal Tunnel syndrome 5. Abnormal growth 6. Giantism 7. Acromegaly

HGH will mobilize what

Free fatty acids from adipose tissue to be used as an energy source

IGF1 also stimulates the growth of what

other tisses

HGH will promote what

protein synthesis and cellular uptake of protein and amino acids

HGH is produced by what

the anterior pituitary gland

HGH will decrease what

the breakdown of protein and amino acids

IGF1 promotes what

the deposition of collagen and chondroitin sulfatet

Inection of a recombinant (synthetic) HGH was made possible by what

the production of HGH in a laboratory in 1986

HGH is partially converted to what

growth factors

The availability secretion of HGH peaks when

in adolescence and early adulthood and then decreases afterwards