Human Growth Hormone
Under the influence of HGH fats may be used in preference to what
-Carbohydrates and proteins for energy
Production of HGH may be stimulate during what
-Starvation -Fasting
HGH does NOT *directly* affect what
-bone -cartilage growth
HGH is critical for what
1. Tissue repair 2. Muscle growth 3. Brain function 4. Bone strength 5. Metabolic balance
What is the best way to determine the adequacy of HGH in the body
By checking IGF levels
Where does IGF1 form and as a result of what?
In the liver and possibly the kidneys as a result of stimulation by HGH
What was the original method used to treat children with growth deficiencies
Injection of natural HGH
It is difficult to measure HGH levels why
It is rapidly used up and absorbed by the liver. It does not last long in the blood stream
What promotes the basis for most over the counter HGH supplements
People claiming that ingestion of certain amino acids will stimulate the production and the release of HGH
What are symptoms of acromegaly
1. Distorted bone and skull development 2. Kyphosis 3.Enlargement of tongue, Kidneys, and Liver
Insulin like Growth Factor 1 is also called what
Somatomedin C
Human Growth Hormone is also called what
Somatotropin
Secretion of HGH responds to what
changes in protein and carbohydrate levels
Blood concentration of HGH varies how
during the day and can change VERY rapidly
Where does IGF1 stay?
in the blood stream for an extended period of time
Chondroitin sulfate is necessary for what
the growth of cartilage and bone -Because HGH promotes the formation of IGF1 it *INDIRECTLY* promotes bone growth
What are the results of HGH deficiency?
1. Inadequate cell maintenance and repair 2. Inadequate growth 3. Dwarfism 4. Protein breakdown- bc it usually inhibits its breakdown 5. Reduced energy levels
What are the results of an excess of HGH
1. Joint pain 2. Fluid retention 3. Hypertension 4. Carpal Tunnel syndrome 5. Abnormal growth 6. Giantism 7. Acromegaly
HGH will mobilize what
Free fatty acids from adipose tissue to be used as an energy source
IGF1 also stimulates the growth of what
other tisses
HGH will promote what
protein synthesis and cellular uptake of protein and amino acids
HGH is produced by what
the anterior pituitary gland
HGH will decrease what
the breakdown of protein and amino acids
IGF1 promotes what
the deposition of collagen and chondroitin sulfatet
Inection of a recombinant (synthetic) HGH was made possible by what
the production of HGH in a laboratory in 1986
HGH is partially converted to what
growth factors
The availability secretion of HGH peaks when
in adolescence and early adulthood and then decreases afterwards