Hyperprolactinemia definitions
dopamine antagonists
A class of drugs that that can cause hyperprolactinemia.
prolactin inhibits:
GnRH secretion
prolactinoma
The most common type of pituitary tumor. It hypersecretes prolactin.
The first line of treatment for hyperprolactinemia is usually medical treatment with a:
dopamine agonist
Hyperprolactinemia
high prolactin secretion
hypogonadotropic hypogonadism
low gonadal function that results from low gonadotropin secretion
A concern is that decreased gonadal steroid secretion will lead to:
osteoporosis
Prolactin
the hormone that stimulates milk production in the breast
lactation
the secretion of milk by the mammary glands.
oxytocin
a hormone released from the posterior pituitary that causes milk ejection.
dopamine
a hormone, traveling to the anterior pituitary via the hypophyseal portal vessels to inhibit prolactin secretion by anterior pituitary cells.
galactorrhea
abnormal milk production
anovulation
absence of ovulation
2 dopamine agonists that are approved for the treatment of hyperprolactinemia are:
bromocriptine and cabergoline