Hyperprolactinemia definitions

dopamine antagonists

A class of drugs that that can cause hyperprolactinemia.

prolactin inhibits:

GnRH secretion

prolactinoma

The most common type of pituitary tumor. It hypersecretes prolactin.

The first line of treatment for hyperprolactinemia is usually medical treatment with a:

dopamine agonist

Hyperprolactinemia

high prolactin secretion

hypogonadotropic hypogonadism

low gonadal function that results from low gonadotropin secretion

A concern is that decreased gonadal steroid secretion will lead to:

osteoporosis

Prolactin

the hormone that stimulates milk production in the breast

lactation

the secretion of milk by the mammary glands.

oxytocin

a hormone released from the posterior pituitary that causes milk ejection.

dopamine

a hormone, traveling to the anterior pituitary via the hypophyseal portal vessels to inhibit prolactin secretion by anterior pituitary cells.

galactorrhea

abnormal milk production

anovulation

absence of ovulation

2 dopamine agonists that are approved for the treatment of hyperprolactinemia are:

bromocriptine and cabergoline