microbiology
Chlamydia transmission
- sexual contact (can be spread to mouth and throat) - woman to infant during childbirth
Rickettsia typhi
-Endemic typhus -Fleas
what are the reasons of concern with candida auris
1.It is often multi-drug resistant; resistant to antifungal drugs commonly used to treat Candida infections. 2. It has caused outbreaks in healthcare settings. For this reason, rapid identification of C. auris in a hospital patient is particularly important so that hospitals can take special precautions to stop its spread. 3. It is difficult to identify with standard laboratory methods, and can be misidentified without special technology. Misidentification leads to inappropriate treatment,
chlamydia
A sexually transmitted disease, the most common in developed countries, caused by the bacterium Chlamydia trachomatis. Often producing no symptoms, it can cause infertility, chronic pain, or a tubal pregnancy if left untreated. Chlamydia trachomatis
rocky mountain spotted fever symptoms
A week after tick bite: -High fever -N/V -Muscle aches/arthralgias -malaise -Rash = red macule/papules to petechiae on wrists/palms and ankles/soles, spreading centrally to trunk (Can be fatal if not treated) --- can become necrotic
tinea cruris
A. Jock itch (groin area)
epidemic typhus
Bacterial disease caused by Rickettsia and transmitted by the body louse. Outbreaks often associated with times of conflict and war; historically, the course of conflicts were often regulated in part by the disease.
Tinea symptoms
Blister-like lesions - fluid discharge when scratched, cracks- open fissure - bacterial contamination
Rocky Mountain Spotted Fever
Caused by Rickettsia rickettsii Sx: rash on palms and soles (migrating to wrists, ankles, then trunk), HA, fever. Endemic to East Coast (in spite of its name).
Rickettsia akari
Causes rickettsial pox
Most common STD
Chlamydia
elementary bodies
Chlamydia spp live as ________ when they need to survive outside of a host cell. INACTIVE FORM A small dormant body that serves as the agent of transmission between hosts cells in the chlamydial life cycle.
epidemic typus transmission
Cold climates, poor sanitation, crowding during natural disasters, famine, infrequent Scratch into wound Inhalation Blow into eyes
Rickettsial pox is caused by
Common house mite from common house mouse
rickettsia typhi transmission
Rat flea bite --- deficate on skin - enters bite, Can contaminate clothes. common in rats
brill zinsser disease
Recurrences of rickettsia prowazaki up to 50 yrs later --recurrence of endemic typhus
Brill-Zinsser disease
Recurrences of rickettsia prowazaki up to 50 yrs later remains infected for long periods of tim
rickettsial pox
Rickettsia akari --- no WF reaction
Rickettsia transmission
Rickettsia infections often involve a characteristic rash and tick, lice or flea vectors.
epidemic typhus is caused by
Rickettsia prowazekii and transmitted by body lice. It is associated with war, famine and poverty.
rocky mountain spotted fever cause
Rickettsia rickettsia, spread by ticks
Spotted fever group
Rickettsia rickettsii ------Rocky mountain spotted fever
Scrub typhus cause
Rickettsia tsutsugamushi ( mites)
The most common rickettsial disease in the US is
Rocky Mountain Spotted Fever
Rickettsia
Small bacteria that live in lice, fleas, ticks, and mites that transmit infection to humans.
Sporotrichosis is caused by
Sporothrix schenckii
reticulate body
The form of chlamydiae that replicates and produces elementary bodies within the mucosal cell metabolically active
eschar
a thick layer of dead tissue and tissue fluid that develops over a deep burn area
Candida auris is diagnosed with
are usually diagnosed by fungal culture of blood or other body fluids, but can be confused with other types of Candida, especially Candida haemulonii.
dying patients that have epidemic typhus exhibit what symptoms
encephalitis, myocarditis, interstitial nephritis and shock.
rickettsia typhi
endemic typhus --- transmitted by fleas
rickettsial pox symptoms
eschar Fever malaise headache M-P rash on face, trunk, extremities, becomes vesicular like chicken pox.
Scrub typhus symptoms
eschar Sudden onset of headache fever pneumonia macular rash lymphadenopathy and hepatosplenomegaly
Endemic typhus symptoms
fever headache malaise myalgias nausea RED MACULAR RASH ---- starts in the trunk and spreads to the extremities --- no rash on the hand, feet or head
tinea pedis
fungal infection of the foot; athlete's foot athlete's foot
tinea capitis
fungal infection of the scalp
is rickettsia gram negative or gram positive
gram negative
which age group is susceptible to rocky mountain spotted fever
individuals younger then 19 years old are usually at risk males affected twice as often as females it is common during summer months
Weil-Felix Reaction
is an agglutination test for the diagnosis of rickettsial infections. an agglutination test for various rickettsial infections (as typhus and Rocky Mountain spotted fever) using particular strains of bacteria of the genus Proteus that have antigens in common with the rickettsiae to be identified
Rocky Mountain Spotted Fever is caused by
is caused by Rickettsia rickettsii which is transmitted by hard ticks.
scrub typhus symptoms can progress to which fatal conditions
meningoencephalitis myocarditis shock.
tinea barbae
ringworm of the beard
tinea corporis
ringworm of the body
tinea unguium
ringworm of the nails
ROSE THORN DISEASE causative agent
sporotrichosis
Sporothrix schenckii
sporotrichosis (rose pickers disease)
dermatomycoses
Informally known as tineas or ringworm
most susceptible patients for candida auris
Most vulnerable are fragile hospital patients - particularly newborns and the elderly. Patients who have been in the ICU for a long time or have a central venous catheter placed in a large vein, and have previously received antibiotics or antifungal medications, appear to be at highest risk of infection.
Rickettsia typhi
Murine typhus (endemic typhus) spread by fleas bites
rocky mountain spotted fever treatment
Doxycycline, chloramphenicol effective if given early prior to irreversible organ damage -- no vaccine
candida auris
Emerging global health threat Resistant to all three major classes of antifungals Can persist on surfaces and *spread between* patients --- ANTIBIOTIC RESISTANT This puts the pathogen on the ever-growing list of superbugs resistant to many, and in some cases, all antibiotics. This yeast can enter the bloodstream and spread throughout the body causing serious invasive infections. This fungi is resistant to ALL antifungal agents!!
Rickettsia prowazekii
Epidemic typhus Spread by lice