Pharamacology EAQ Chapter 2

The nurse is working in a clinical trial for which healthy volunteers are being recruited. Which phase of the clinical trial is the nurse participating in? Phase I Phase II Phase III Phase IV

Phase I Phase I is a clinical trial in which healthy volunteers are used to determine the optimal dosage range and the pharmacokinetics of the drug

What basic ethical principle involves autonomy as an integral component in research involving human studies. Justice Veracity Beneficence Respect for persons

Respect for Persons Autonomy is the right to self determination. Integral component for respect.

A nurse is teaching a group of new nurses about the use of OTC medications. Which statement by the new nurse indicates a need for further explanation. "Be wary of overdosing when using OTC products." "Read specific warning labels before taking OTC products." "OTC cold products are safe in children younger than 2 years of age." "Do not use OTC products if you have cardiovascular disease."

"OTC cold products are safe in children younger than 2 years of age." OTC cold products can lead to seizures, tachycardia, over sedation, and death. If you have cardiovascular disease you can use products, but you should check with your healthcare provider first.

A patient who is prescribed a Schedule II drug expresses concern to the nurse that they must arrange for another appointment with the health care provider before receiving another prescription for the medication. What is the most appropriate response by the nurse. "Your doctor will need to know how you feel before you get another prescription.: "Insurance companies have specific rules regarding reimbursement." "The drug has the potential for severe psychological and physical dependence." "You'll be finished with the medication soon, so don't worry about it."

"The drug has the potential for severe psychological and physical dependence." The HCP doesn't need to know how the patient feels, but does need to do a physical assessment. Insurance companies do have rules about reimbursement, but that's irrelevant to the follow up appointment. The nurse doesn't know when the patient will be finished with the medication.

A nurse is studying basic ethical principles that are relevant to research involving human subjects. Which statement indicates that that the nurse understand the ethical principle autonomy? "The patient can withdraw from a research study but will penalized." "The patient has the right of self-determination." "The patient can refuse all treatments even if it poses a risk to other patients." "The purpose of autonomy is to minimize harm that might occur in research."

"The patient has the right of self-determination." Beneficence- is the duty to not harm others, maximize possible benefits and minimize possible harm that might occur in research.

What resource provides the basis for standards in drug strength and composition throughout the world? United states pharmacopeia/national formulary American hospital Formulary Service (AHFS) MedlinePlus International Pharmacopeia

International Pharmacopeia

The nurse who treats all patients fairly is demonstrating which ethical principle? Justice Beneficence Autonomy Veracity

Justice

The nurse is caring for a patient with end-stage cancer. The nurse notes a Schedule I drug in addition to anticancer drugs in the patient's prescriptions. Which drug would require increased monitoring due to it's Schedule I status. Marijuana Phenobarbital Diazepam Aprazolam

Marijuana (Nabilone) Marijuana is a Schedule I drug according to the Controlled Substances Act of 1970.

While reviewing the medication history of a patient, the nurse finds medication with a high potential for drug abuse and strong physical and psychologicals dependency. Which schedule medication does the nurse identify in the patient's medical records. Schedule II Schedule V Schedule IV Schedule III

Schedule II controlled medication include oxycodone, codeine, amphetamines, secobarbital, meperidine, morphine, and hydrocodone. These substances have high potential for drug abuse and can cause strong physical and psychological dependency.

An investigational drug completes a Phase III trial; however the drug cannot enter the market. Which statement describes the possible reason for this? The new drug isn't approved by the FDA The new drug needs more data for confirm its safety The manufacturer doesn't have funds to finance the drug The new drug is not in demand in the market

The new drug isn't approved by the FDA. Once Phase III is complete, an investigational new drug application is submitted to the FDA.

How is a preclinical study of a drug different from a clinical study? preclinical includes both vitro and in vivo studies preclinical analyzes the risk-benefit ratio of the drug preclinical incorporates experimental and control group preclinical establishes the safe therapeutic dose for human experimentation

preclinical includes both vitro and in vivo studies preclinical studies involve experimentation on animals. clinical studies are carried out on humans. Both clinical and periclinal analyze the risk benefit ratio and include an experimental group and a control group and also both establish safe therapeutic dose for human experiementation.

Which drug phase defines an "orphan drug" Treat cancer symptomatic relief treat rare illness treat common mental illness

treat rare illness Orphan Drug Act 1983

A patient is prescribed a Schedule III drug. The patients asks the nurse what the schedule designation means. How are the Schedule III drugs classified Risk for toxicity Potential for abuse Adverse Effects Pain relief provided

Potential for abuse Schedule designation occurs based ont eh drug's potential for abuse and dependence; therefor Schedule III and all other drugs on the schedule are classified according to their potential for abuse and dependence.

The patient is making his or her own decisions regarding health care. The patient is demonstrating which ethical principle. Justice Beneficence Autonomy Veracity

Autonomy Autonomy is the right to self determination. In health care settings, health care personnel must respect patient's rights to make decisions about themselves, even if the decisions is not what we think is right.

The nurse is assessing a patient with cancer who is unable to adhere to the medication regiment due to the high cost of medication. Which treatment strategy does the nurse anticipate being most beneficial for the patient Prescribing generic drugs Prescribing Schedule I drugs Prescribing controlled substances Prescribing medication undergoing clinical trial

Prescribing generic drugs Generic drugs have the same active ingredients as brand-name drugs and are usually less expensive. These medications may be prescribed to prove cost-effective treatment. Although some controlled substances are use in cancer treatment, prescribing these does not address the patients inability ot pay. Clinical trial drugs are not safe yet.

A patient has consented to participate in a drug study. Which statement describes the nurse's role in the informed consent procedure. It depends on the type of study The nurse is responsible to educate the patient about the study The nurse's role is to protect the patient from anticipated harm The nurse's role is to write out the consent form

The nurse's role is to protect the patient from anticipated harm. The nurse's responsibility does not vary depending on the study The HCP is responsible for teaching the patient and writing the informed consent form