Pharmacology

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Therapeutic level for Phenytoin

10-20

Therapeutic Level for Warfarin

2-3

How long does it take for Antidepressants to work?

2-3 weeks

Loop Diuretics end in

-Nide and -Mide

Therapeutic level of Digoxin

0.5-2

What is the therapeutic level of lithium?

0.6-1.2. Take action when its over 1.5

What is Tramadol?

A opiate analgesic used for moderate to severe pain.

What type of drug is Enlapril?

ACE Inhibitor

Antihypertensives

ACE Inhibitors ARBS Calcium Channel Blockers Beta Blockers

What happens when Phenytoin is given with an Antacid?

Antacids will reduce the absorption of Phenytoin

Ciprofloxacin is what type of drug?

Anti-Infective. Fluroquinolones

What is Atropine?

Antiarrhythmic & Anticholinergic

Vancomycin is what type of drug?

Antibiotic

What should you monitor for when taking TCAs?

Anticholingeric effects Can't See Can't Pee Can't Spit Can't Shit

Phenytoin is what type of drug?

Anticonvulsant

Ondansetron is what kind of drug?

Antiemetic

What type of drug is Haloperidol?

Antipsychotic

What type of drug is fluphenazine decanoate?

Antipsychotic. Used to treat schizophrenia

What type of drug is Acetaminophen?

Antipyretic (reduce fever) Non-opioid analgesic

What type of drug is Aspirin?

Antipyretic and non-opioid analgesic

What is Ativan used for?

Anxiety, Sedation, Seizures

What should you avoid when taking MAOIS?

Avoid foods that are high in tyramine (Aged cheeses, Wine, Pickled meats)

Nursing Considerations for Atropine

Avoid in patients with glaucoma

What renal labs to monitor when taking antibiotics

BUN and Creatinine

What should be avoided when doing an electroconvulsive therapy program?

Benzodiazepines

What is Propranolol?

Beta Blocker

Steroids

Betamethasone Dexamethasone Cortisone Fluticasone Methylprednisolone

What is Lithium used for?

Bipolar Disorder. (Mania)

Gastrointestinal Medications

Bisacodyl Lactulose Metoclopramide Ondansetron Omeprazole Pantoprazole

What is the common side effect of t-PA?

Bleeding. Important to check the insertion sites

Respiratory Medications

Albuterol Ipratropium Guaifenesin Montelukast Theophylline

What is Diphenhydramine used for?

Allergy, Anaphylaxis, Sedation

Gentamycin is what type of drug?

Aminoglycoside - Anti-Infective

Antiarrhythmics

Amiodarone Adenosine Procainamide Atropine

TCAs (Antidepressants)

Amitriptyline Nortriptyline Protriptyline

Calcium Channel Blockers

Amlodipine Diltiazem Nifedipine Verapamil

Anti-Infectives - Penicillin & Cephalosporins

Amoxicillin Ampicillin Ancef

Antifungals

Amphotericin B Metronidazole Nystatin

What is Ativan?

An antianxiety agent. Benzodiazepiene. Lorazepam

What is Adenosine?

An antiarrhythmic medication

What type of drug is Albuterol?

Bronchodilator, short acting beta 2 agonist, respiratory medication

Loop Diuretics

Bumetanide Furosemide Torsemide

What is Aspirin used for?

Pain, Arthritis, Stroke and Myocardial Infarction Prophylaxis

What are NSAIDS used for?

Pain, Inflammation, Fever

Risk factors for Digoxin toxicity

Patients with hypokalemia The Elderly

Anticonvulsants

Phenytoin (Dilantin) Carbamazepine Divalproex Gabapentin Lamotrigine Levetiracetam (Keppra)

Phenytoin should not be given with what drug at the same time?

Calcium Carbonate (TUMS) (Antacids)

Nursing Consideration of Ciprofloxacin

Can cause QT Prolongation

Nursing Considerations for ACE Inhibitors

Can cause a dry cough

Nursing Considerations for NSAIDS

Can cause prolonged bleeding and peptic ulcers

ACE Inhibitors

Captopril Enalapril Lisinopril

The action of Aspirin

Decrease platelet aggregation leading to a decrease in ischemic diseases

What medication is used to control bleeding a child with hemophilia A?

Factor VIII

True or False: Warfarin is given during pregnancy

False

What is Acetaminophen used for?

Fever and Pain

Side effects of hydrocortisone therapy

Fluid retention and edema

What is the antidote for antianxiety agents (benzodiazepines)?

Flumazenil

What is the antidote for Ativan?

Flumazenil. Remember Ativan (Lorazepam) is a benzodiazepine

SSRIs (antidepressants)

Fluoxetine Sertraline Escitalopram Citalopram

A newborn whose mother has type 1 diabetes has been receiving a continuous infusion of fluids with glucose. Which would the nurse do when there is an order to discontinue the infusion?

Gradually decrease the rate

What are calcium channel blockers used for?

Hypertension, Angina

What are ACE Inhibitors used for?

Hypertension, Congestive Heart Failure

What is Enlapril used for?

Hypertension, Congestive Heart Failure

What is Losartan used for?

Hypertension, Diabetes Mellitus Neuropathy, Congestive Heart Failure

What is a huge side effect of taking MAOIs?

Hypertensive Crisis

Nursing Consideration for Digoxin

If pulse is less than 60, hold the digoxin

NCLEX Tip

If you never heard of a medication, do not choose it on the exam.

NCLEX Tip

If your patient is on a loop diuretic and digoxin, they are more likely to become toxic. Be careful with black licorice

A verbal response of 2 on a Glasgow Coma Scale

Incomprehensible sounds

Nursing considerations for ampicillin

Increase fluid intake

Nursing Consideration for Anticoagulants

Increased risk for bleeding

Oxytocin is given for what?

Inducing Labor Postpartum Hemorrhage

How is alopecia areata treated?

Intralesional injection

Why are NSAIDS not used post operation?

It can prolong bleeding

Antibiotics can harm what

Kidneys. It can be nephotoxic.

Diuretics

Loop Diuretics Potassium Sparing Diuretics Thiazide diuretics

Angiotensin II Receptor Blockers (ARBS)

Losartan

What are statins used for?

Lower the bad cholesterol (LDL)

What are Beta blockers used for?

Lower the heart rate. Myocardial Infarction. Angina/Chest Pain

Nursing Considerations for Acetaminophen

Maximum daily dose is 4 grams

Antianxiety Drugs (Benzodiazepines)

Midazolam Alprazolam Clonazepam Lorazepam Diazepam

A patient is experiencing severe, acute anxiety before a procedure. Which antianxiety agent would you give?

Midazolam. It has rapid onset

Nursing Considerations for Oxytocin

Monitor contractions Monitor fetus

Nursing Considerations for Haloperidol

Monitor for extrapyramidal side effects Tardive dyskinesia Neuroleptic Malignant Syndrome Can prolong the QT Interval

Nursing Considerations for Magnesium sulfate

Monitor for hypermagnesemia (decreased reflexes) Give IV slowly

Nursing Considerations for Loop Diuretics

Monitor potassium levels

Nursing Considerations for anakinra therapy

Monitor the injection sites Monitor the neutrophil count Can cause respiratory problems

Opiods

Morphine Fentanyl Hydromorphone Methadone Oxycodone

Antidote for acetaminophen toxicity

N-acetylcysteine

The antidote for Morphine

Naloxone

Nursing Considerations for Gentamycin

Tinnitus Do not administer with penicillin

Obstetric/Maternity Medications

Tocolytics Oxytocics

MAOIs (antidepressants)

Tranylcypromine Isocarboxazid Phenelzine Selegiline

What are Antipsychotics used for?

Treat schizophrenia

What is sodium hyaluronate?

Treats pain in the knee caused by osteoarthritis

Potassium Sparing Diuretics

Triamterene Amiloride Spironolactone

What type of drug is rifampin?

Tuberculosis medication

What type of medication is isoniazid?

Tuberculosis medication

What type of medication is pyrazinamide?

Tuberculosis medicatipn

What is the antidote for warfarin?

Vitamin K

What is a side effect of ceftriaxone?

allergic reactions such as rash, urticaria, pruritus', and angioedema

What is amlodipine?

calcium channel blocker

Nursing Considerations for Vancomycin

Red-man syndrome Monitor for ototoxicity (ears) and nephrotoxicity

Nursing Considerations for Omeprazole

Report black, tarry stools

What does anakira therapy treat?

Rheumatoid arthirits

Nursing Considerations for Aspirin

Risk for bleeding In Pediatric patients it can cause Reye syndrome

What type of medication is Duloxetine?

SNRI (Antidepressant)

What drugs are the first line therapy for depression?

SSRIs

Antidepressants

SSRIs, TCAs, MAOIs

What is the main side effect of fluoroquinolones?

Tendon rupture

Tocolytics

Terbutaline Magnesium-Sulfate Indomethacin (prostaglandin inhibitor) Nifedipine (Calcium channel blocker)

Side effect of quetiapine

cataracts

A verbal response of 5 on a Glasgow Coma Scale

Speech is well oriented

Nursing Considerations for SSRIs

Suicide Precautions

Treatment for Heparin Induced Thrombocytopenia and Thrombosis

Discontinue Heparin and use a different anticoagulant

What is magnesium sulfate used for?

Pre-eclampsia Preterm Labor

What is a side effect of isoniazid?

hepatitis

What is clomiphene?

infertility drug, selective estrogen receptor modulator (SERM), used to induce pregnancy by triggering pregnancy

Which anticoagulant can be given during pregnancy

low molecular weight heparin

What is Cyclobenzaprine hydrochloride?

muscle relaxer

What is Ondansetron used for?

nausea and vomiting

Side effects of ampicillin

nephrotoxicity, oliguria, hematuria, proteinuria, and glomerulonephritis.

What is a side effect of ethambutol?

ocular toxicity

What is a Diclofenac epolamine patch?

pain relief for strains, sprains and bruises. It is an NSAID

What type of drug is Omeprazole?

proton pump inhibitor

What is Haloperidol used for?

schizophrenia

What do tocolytics do?

slow contractions

What do Oxytocics do?

stimulate contractions

What is Adenosine used for?

supraventricular tachycardia (SVT)

What does an infant receive a Vitamin K shot?

the infant's intestine is sterile at birth, it lacks the flora to synthesize vitamin K, which activates coagulation factors and prevents hemorrhage in the newborn.

Therapeutic Level for Warfarin for patients who have heart valves

2.5-3.5

What is quetiapine?

2nd gen antipsychotic

How long does the effect of aspirin last?

5-7 days. It should be stopped 5-7 days before a surgery

What is Losartan?

ARB

Non-Opioid Analgesics

Acetaminophen NSAIDS (Aspirin, Ibuprofen, Naproxen)

Anti-Virals

Acyclovir

Nursing Considerations for Ondansetron

Administer slowly. Fast push can cause QT Prolongation and Ventricular Tachycardia

Acetylsalicylic Acid is known as what

Aspirin

What is Albuterol used for?

Asthma, COPD

Thiazide Diuretics

Chlorothiazide Chlorthalidone Hydrochlorothiazide Indapamide

Anti-Infectives - Fluroquinolones

Ciprofloxacin Levofloxacin

Complications of Heparin Induced Thrombocytopenia and Thrombosis

Clotting

Nursing Considerations for Morphine

Common side effect is Constipation Monitor respiratory rate

What is Heparin Induced Thrombocytopenia and Thrombosis?

Complication of Heparin therapy. Unexplained low platelet count

A verbal response of 4 on a Glasgow Coma Scale

Confusion

Methylprednisolone is what type of drug?

Corticosteroids

Side effects of ACE Inhibitors

Cough, Angioedema (tongue swelling)

What are MAOIs used for?

Depression

What are SSRIs used for?

Depression

What are TCAs used for?

Depression

Side effects of Cephalosporins

Diarrhea and Nephrotoxicity

Cardiac glycosides

Digoxin

Antihistamines

Diphenhydramine (Benadryl) Promethazine Cimetidine Famotidine Ranitidine

What is a side effect of rifampin?

Discoloration of body fluids (i.e. orange sweat) Thrombocytopenia

What should you do next if clomiphene therapy fails?

Do human chronic gonadotropin and gonadotropin-releasing hormone to stimulate ovulation.

Nursing Considerations for Beta Blockers

Do not discontinue abruptly Can mask the signs of hypoglycemia (need to monitor blood sugars)

Side effects of sertaline

Dry mouth and constipation

Medication used to treat generalized anxiety disorder and depression

Duloxetine

Side effects of fluphenazine decanoate?

Dystonia. Torticollis. Oculogyric crisis

What are the side effects of oxytocin?

Edema, Headache, Confusion, Blurred vision, uterine rupture

Anti-Infectives - Macrolides

Erythromycin Azithromycin

What is Atropine used for?

Excessive secretions, Sinus Bradycardia, Heart Block

Sign & Symptoms of Diabetic Ketoacidosis

Excessive thirst, frequent urination, nausea and vomiting, abdominal pain, weakness or fatigue, shortness of breath, fruity scented breath, and confusion

What are the side effects of aspirin?

Ototoxicity (ears), tinnitus. Gastrointestinal irritation. Blood in the stool

What is Omeprazole used for?

GERD and ulcers

Anti-Infectives - Aminoglycosides

Gentamicin

Oxytocics

Oxytocin Ergometrine (Methergine) Misoprostol

Antipsychotics

Haloperidol Quetiapine Olanzapine

How is methadone different compared to other opiates?

Has a longer duration

What is Digoxin used for?

Heart Failure, A-Fib, A-Flutter, Cardiogenic shock

Anticoagulants

Heparin Clopidogrel (Plavix) Warfarin Enoxaparin (Low Molecular Weight)

The main risk factor for using inhaled glucocortisterioids?

Oral candidiasis

Beta Blockers

Propranolol Atenolol Metoprolol

Antidote for Heparin

Protamine Sulfate

What are anticonvulsants used for?

Seizures

What should you monitor for when taking SSRIs?

Serotonin Syndrome

Quick Relief or Rescue Medications for an acute asthma attack

Short acting beta 2 agonists and anticholinergics (Atropine)

What does Heparin do?

Slows down clotting

Nursing Considerations of Adenosine

There will be a period of asystole after administration Rapid push or it will not work

What are antiarrhythmics used for?

Used for correcting abnormal rhythms in the heart

Anti-Infectives - Antibiotic

Vancomycin

Symptoms of digoxin toxicity

Vision changes, blurred vision, yellow/green vision, Nausea/Vomiting, Anorexia, Bradycardia

Huge side effect of calcium channel blockers

gingival hyperplasia

What is a side effect of pyrazinamide?

hyperuricemia

A verbal response of 3 on a Glasgow Coma Scale

inappropriate words

What type of drug is ethambutol?

tuberculosis medication


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