Pharmacology Chapter 36 - Multiple Choice

A patient presents with dehydration. Following ACTH administration, plasma cortisol levels cannot be detected. The mostly likely diagnosis for this patient is

Addison's disease

The regulation of cortisol secretions involves which of the following?

diurnal rhythm, negative feedback triggered by elevated circulating cortisol levels, stress, and circadian rhythm

Which of these effects is not associated with long-term steroid therapy?

increased muscle strength

Select the true statement about dexamethasone

it is a naturally occurring steroid

A patient taking prednisone long term (chronically) might develop which of the following adverse effects?

moon face or buffalo lump

The advantage of a repository preparation of a glucocorticoid is

prevention of edema in the joint

Which of the following is not true of mineralocorticoids like fludrocortisone?

regulate fluid balance

A patient diagnosed with rheumatoid arthritis is in remission, and the physician tells the patient to discontinue her prednisone. Which important advice would the physician give to his patient?

taper the medication dosage down over the next few months

Which of the following is correct about the mineralocorticoids?

they are secreted by the adrenal medulla

Which of the following is not a function of secreted glucocorticoids:

transcription of nucleus DNA