Regulations and Facilities-RATS Final Exam Review

True or False? Each animal research institution must establish and maintain an occupational safety and health program as a part of the overall program of animal care and use.

True

True or False? Red light is imperceptible to rodents, but can be seen by humans. Red lights are commonly used in research facilities for fire alarm notifications or to check on rodents during the dark light cycle.

True

True or False? Scientists use animals for research when they have provided assurance to the IACUC that no non-animal methods will allow them to achieve their scientific aim.

True

True or False? The NIH will not fund research that utilizes dogs and cats from random sources (class B dealers).

True

True or False? Animal feed in a research facility may be stored on the floor.

False

True or False? Aseptic techniques are not needed when performing surgery on rats as they are inherently resistant to surgical infection.

False

True or False? The terms "animal welfare and "animal rights" are synononymous.

False

How many air changes per hour (ACH) are recommended for animal housing rooms in a research facility? a. 20-25 b. 10-15 c. 5-10 d. 15-20

10-15

What is the suggested temp to achieve sanitation in an automated cage washer? a. 280ºF b 250ºF c. 160ºF d. 180ºF

180ºF

What is an appropriate relative humidity range for most terrestrial animal housing rooms in biomedical research?

30-70%

Most dry animal diets that are properly stored can be used up to ______ after the manufacture date. a. 6 months b. 9 months c. 3 months d. 1 year

6 months

How often is IACUC required to inspect all animal care facilities and study areas? a. Every year b. Every 6 months c. Every 3 months d. Every 3 years

Every 6 months

AALAC International

Administers a voluntary accreditation program of laboratory animal care

How often does a veterinary medical officer (VMO) from USDA perform site inspections at biomedical research facilities? a. every 3 years b. every 6 months c. every 2 years d. at least annually

At least anually

Which of the following is NOT an acceptable reason to singly house animals of a social species? a. Cost b. Veterinary concerns regarding animal well-being c. Scientific necessity d. Observed social incompatibility (ex: fighting)

Cost

PHS Policy

Defines laboratory animals as "any vertebrae used in research, testing, or education"

ILAR

Develops guidelines and disseminates information to the federal government on scientific, technological, and ethical use of animals

FDA

Federal agency that requires animal testing of products when a scientifically valid, alternative testing method is not available

What does FBR stand for?

Foundation for Biomedical Research

What does the acronym IACUC stand for?

Institutional Animal Care and Use Committee

What does LATg stand for? a. Laboratory Animal Technician Global b. Laboratory Animal Technologist c. Laboratory Animal Technical Specialist d. Limited Animal Teaching Goal

Laboratory Animal Technologist

FD&C

Law created to safeguard and protect consumer health and safety from the sale of dangerous products

NIH

Main public agency for biomedical research

Which of the following species is not covered by the AWA?

Mice bred for research

Which of the following features of walls should be incorporated to facility design for an animal housing room in a research facility? Select all that apply. a. Minimal sound transmission b. Impervious to moisture c. Fire-resistant d. as seamless as possible

Minimal sound transmission, fire-resistant, impervious to moisture, as seamless as possible.

AALAS

Nonprofit organization that serves as the principal means of communication between individuals and organizations within the field of laboratory animal science

Operating rooms are clean rooms. What type of room pressure is recommended for operating rooms?

Positive

Which governing body is responsible for the interpretation and implementation of the Public Health Service Policy on Humane Care and Use of Laboratory Animals? a. OLAW b. FDA c. USDA d. EPA

OLAW

What does the acronym OLAW stand for?

Office of Laboratory Animal Welfare

AWIC

Part of the National Agriculture Library

What does PPE stand for? a. Personal Protective Equipment b. Protective Paper Essentials c. Prickly Pear Eatery d. Personal Party Expert

Personal Protective Equipment

IACUC

Prior to use of animals in research, testing, or training, a protocol must be approved by this committee

A researcher at you institution has updated their animal use protocol to deliver medications to nonhuman primates in food treats instead by injection. Which of the 3Rs is this applying?

Refinement

Cleaning

Removes excess amounts of excrement, dirt, and debris.

ACLAM

Speciality board recognized by the AVMA

Sanitation

The maintenance of environmental conditions conductive to health and well-being.

Which governing body is responsible for enforcing the AWA?

USDA

Sterilization

Validated process to render a product free from all forms of viable microorganisms.

What do humane endpoints help determine?

When an animal should be euthanized or removed from a study

the cost to maintain one animal (or cage of animals) for one day is called what?

per diem

Disinfection

reduces or eliminates unacceptable concentrations of microorganisms.

LAT

AALAS certification level for technicians who have achieved diagnostic and technical skills

Which of the following animal biosafety level designations involves the highest level of risk? a. ABSL 4 b. ABSL 2 c. ABSL 3 d. ABSL 1

ABSL 4

AWR

Interprets the Animal Welfare Act into enforceable standards