Unit 11: Infection
for one pt infected with d diff, how many pts will become colonized on average
5-10
rate of hai in the average ICU is _____ than in an average hospital area
5-10 times greater. the pts are sicker there are lots of germs, there's more touching by HCP, there are more tubes, more procedures. more risk
human mouth is gross and gives boxer infection
:) - so don't punch ppl in the face - and if you do, avoid punching their mouth
kill giardia with what?
Flagyl (metronidazole)
virus you get in the south west us from sweeping up dust that field mice pooped in
Hantavirus Pulmonary Syndrome (HPS) is a severe, sometimes fatal, respiratory disease in humans caused by infection with a hantavirus
_____________ disease can refer to any illness that is caused by the type of bacteria called Neisseria meningitidis, also known as ______________. These illnesses are often severe and include infections of the lining of the brain and spinal cord (meningitis) and bloodstream infections (bacteremia or septicemia). ______________ bacteria are spread through the exchange of respiratory and throat secretions like spit (e.g., by living in close quarters, kissing). Meningococcal disease can be treated with antibiotics, but quick medical attention is extremely important. Keeping up to date with recommended vaccines is the best defense against meningococcal disease.
Meningococcal
why does c diff cause diarrhea
Once established, C. difficile can produce toxins that attack the lining of the intestine. The toxins destroy cells and produce patches (plaques) of inflammatory cells and decaying cellular debris inside the colon and cause watery diarrhea.
What's the most ocmmon type of cap
Streptococcus pneumoniae mycoplasma pneumonia haemophilus influenzae.
when can you see someones health information and it's not a hippa violartion
accidental exposure. in the event of a needle stick, the pt must be tested for certain blood borne diseases like hep and hiv. not violation. info must be shared
pathophysiology of pneumonia
affects both ventilation and diffusion inflammation in alveoli, produces an exudate that interferes with diffusion of oxygen and co2 secretions cause partial occlusion of bronchi and alveoli, which obstructs ventilation bronchospasm arterial hypoxemia (low oxygen)
organism capable of causing disease
agent - pathogen
which precaution requires a negative airflow room and what's the room called
airborn precautions requrire special room airborne infection isolation room with negtive air flow, air isn't returned to inside ventilation system but is filtered through a high efficiency particulate air filter (hepa filter) and exhausted directly outside. all hcp wear n95 respriator
airborne v droplet transmission
airborne is smaller droplets, they can go more than 3 ft, you may need negative pressure and isolation tb is airborne droplet, is larger droplets, can't go more than a meter, examples, meningococcal and influenza
pulmonary sitution resulting from entry of endogenous or exogenous substance into lower airway, substances could include bacteria from upper airway, gastric contents (common) irritating gases or chem contents
aspiration pneumonia
person harboring an organism with s and s., but who is able to transmit infection to others
carrier
common sources of infection in hospital
central lines feeding pumps iv pumps dynomap
the broad street pump outbreak and the outbreak in haiti started by un relief workers
cholera
when a pt with c diff is discharged, what happens to the room
cleaned completely - fomites pass disease
act of a mo invading a pt, growing, and multiplying but not causing disease
colonization
contact precaution infections
colonization or infection with multidrug resistnat orgs like VRE, MRSA, C diff, shigella, other enteric path. major wound infections; herpes simplex; scabies; disseminated varicella zoster; resp syncytial virus;
classifications of pneumonia
community acquired hospital acquired immunocompromised host? aspiration can be caused by bacteria, virus, fungi
occurs either in the community setting or within 48 hours of on patient admission not all cases are hospitialized. specific causative org is identified only 50% of time
community acquired pneumonia or CAP
interval when acute symptoms of infection disappear -- meaning, it's the recovery period
convalescence
droplet precaution infections - larger than 5 microns - 3 ft away
diptheria (pharyngeal), rubella, streptococcal pharyngitis, pneumonia, scarlet fever in infants and young, pertusis, mumps, mycoplasma pneumonia, meningococcal pneumonia or sepsis, pneumonic plague private room or cohort pts; mask or respirator required
what are the conditions that commonly occur to get HAP??
don't know
mechanical vs vector mode of transpportation
don't know - vector is through a living thing, mechanical? from fomite?
what precautions should you wear a mask in for sure
droplet and airborne -- when transporting pt on droplet and airborne precautions, the pt wears a mask
notorious for contaminating water
e coli giardiasis leptosporosis cholera shigellosis campylobacter cryptosporidium parvum
travelers diarrhea - what's the bacteria and how do you get it
e coli, from water
part of the pts normal flora is altered and overgrowth of an organism results - what sort of infection is this?
endogenous
some of the most common endogenous infectinos - what are the culprits
escherichia coli staphylococcus aureus enterococcus pseudomonas klebsiella enterobacter candida staphylococcus epidermis bacteriodes serratia
shunt or fistula infections gotten in the hospital are what sort
exogenous and iatrogenic
HAI acquired from a source outside the pt body like a contaminated instrument
exogenous infection
what shot can aid in pneumonia prevention
flu , and clearly, pneumococcal vaccine
inanimate object that can transmit path b/t ppl
fomite
Hep A Hep B (HBV) Hep C (HCV) modes of transmission
food blood borne blood borne
whats one way to get an intrabdominal infection
gi is punctured during surgery
isolation procedures protective equipment - put on take off order
gown mask eye shields gloves gloves eye shields gown mask
full ppe steps
hand hygient gown mask and eyewear or goggles end with gloves gown mask eye shields gloves gloves eye shields gown mask
HAI
healthcare acquired infection
what's the major means of transmission of path in hospital
healthcare worker hands
bloodborne pathogens - examples
hep b hep c hiv
_________is pneumonia that occurs 48 hours or more after admission and did not appear to be incubating at the time of admission. non s/s on admission
hospital or healthcare acquired pneumonia HAP
organism that harbors a virus or parasite
host
what's the most important reservoir of human infectious disease?
humans
HAI, nosochomial, and one other synonom
iatrogenic infection
an infection after an operation is what sort of infection?
iatrogenic infection -- ....an exogenous infection
interval when pt manifests s and s specific to the sytpe of infection
illness stage
time elapsed bt exposure to a pathogenic organism or a chemical or radiation and when symptoms and signs first appear
incubation period
entry of an org into a host
infection
a state of decline in wellness due to an infection, invasion of the body by mo
infectious disease
the body's cellular response to injury, infection, or irritation is called ___ or _______
inflammation or inflammatory process
used when n95 mask won't fit. it uses positive air. uses a power source to push air through a filter
papr respirator - powered air purifying respirator
infection in pleural space
pleurisy. it hurts when you breathe. - chest wall pain worse when cough
inflammation of the lung cused by various orgs. most common cause of infectious disease death in us 7th leading cause of death in us overall
pneumonia
place or means by which org enter or exit host
portal (of entry/exit)
basic elements of infection control to prevent nosocomial infections
prevention, control surveillance?
what's the period when symptoms are vague, after incubation
prodromal period
occurence of early symptoms that indicate the onset of a disease process - not sure what illness it could be
prodromal stage
example of zoonoses
rabies
a place where a pathogen can survive , may or may not multiply
reservoir
what can result from pneumonia that is in blood
sepsis
potential terrorist infection. how is it spread? what's incupation period?
smallpox airborne or contact spread 7-14 days
everyone in extended care is tested for c diff?
something like that
movement from incubation period to prodromal period
subclinical infection
highest level of respiratory protection. used in hazardous material settings, bio terrorism etc, er will have this - special training to use
supplied air respirator SCBA
used over face to protect you from inhaling particles at a distance of 3 feet or less. used with droplet precautions
surgical mask
degree to which an indi resists a path
susceptibility
tb pt is in a what room operating room is what sort of room
tb is in a negative pressure room operating room is a positive pressure room
nosocomial infections involve what three things to happen
the microorganism / pathogen/ agent of infection/harm the compromised host / pt the chain of transmission / hc worker for ex
what to warn family members about masks
they can make you feel smothered. if they feel that way, leave the room. don't take off mask
means by which an organism is transmitted from host to host
transmission (indirect contact, droplet etc)
precautions everybody gets and what does it mean
universal precautions - standard universal precautions consider all blood and body fluids potentially infectious use personal protective equipemnt to protect
what antibiotic did dennis mention in particulare, can treat c diff diarrhea- is this right?
vancomycin will treat c diff.. -- it is most often caused by fluoroquinolones, cephalosporins, clindamycin and penicillins. (this is not how i wrote it in notes, ask someone)
infectious microbe that is transmitted to people by blood-sucking arthropods. The arthropods (insects or arachnids)
vector
common way to get hap - or specific type of hap
ventilator acquired pneumonia VAP
midl pneumonia name
walking pneumonia
steps to properly wash hands
wet 20 sec wash with soap rince dry turn off with paper towel
can a virus spread at the prodromal stage
yes
flagyl is an antibiotic - can you use it to treat giardia lamblia?
yes, even though it's not a bacteria, it still works
human diseases with animal reservoirs
zoonoses
foodborne infections
intoxication with aftatoxins and botulinum toxin, paralytic shellfish poisoning, staphylococcal food poisoning, typhoid fever, salmonellosis, listeriosis, toxoplasmosis (also cat poop) tapeworms hep A
stages of getting infected
invasion by pathogen through poe (portal of entry) incubation period (pathogen replicates in host, no s and s) prodromal period (early s and s, generic, like fever , fatigue) illness period (clinical s and s) convalescent period (s and s recede - person returns to health) host at this time can become chronic carrier of infectious agent
why not talk so much with a mask
keep respirations to a minimum and a mast that's moist doesn't proveid barrier to mo and is ineffective
legionnaires disease is spread how? what is the name of the pathogen? what is legionnaires disease?
legionnaires disease is spread from old water systems. the mo can live and grow in them. the water is spread out as droplets in AC Legionellosis (LEE-juh-nuh-low-sis) is a respiratory disease caused by Legionella bacteria. Sometimes the bacteria infect the lungs and cause pneumonia — if so, it is called Legionnaires' disease. The bacteria can also cause a less serious infection that seems more like a mild case of the flu. That form of legionellosis is commonly called Pontiac fever.
(also known as field fever,[1] rat catcher's yellows,[2] and pretibial fever[3] among others names) is an infection caused by corkscrew-shaped bacteria called Leptospira. Signs and symptoms can range from none to mild such as headaches, muscle pains, and fevers; to severe with bleeding from the lungs or meningitis.[4][5] If the infection causes the person to turn yellow, have kidney failure and bleeding, it is then known as Weil's disease.[5] If it causes lots of bleeding from the lungs it is known as severe pulmonary haemorrhage syndrome.[5]
leptosporosis
what's a sign of bacterial infection
leukocytosis - wbc above???????
example of disease with vector
maleria, lyme
airborne precaution infections are
measles, chickenpox, disseminated varicella zoster, pulmonary or laryngeal tb require negative pressure airflow; mask or resp protection device like n95 ...
used when caring for pts with known or suspected tb - fit texting is required maybe every year
n95 respirator - duck mask
It includes a ventilation system that generates _______________ to allow air to flow into the isolation room but not escape from the room, as air will naturally flow from areas with higher pressure to areas with lower pressure, thereby preventing contaminated air from escaping the room.
negative pressure
you can kill c diff with alcohol
no! wash them - c diff is a spore forming bacteria. you're best option is to wash and have it go down the drain
no matter where in the body a pathogen enters, if it's a pathogen, it'll cause an infection
nope! it absolutely matters - many organisms that cause one disease if they enter one body site are harmless if they enter another - eg - various enteric uti pathogens