WBCs and Platelets
B
A good presurgical screening test for von Willebrand disease is a(n) (A) Total platelet count (B) Buccal mucosal bleeding time (C) Activated clotting time (D) Activated partial thromboplastin time
A
A left shift refers to increased numbers of (A) Immature neutrophils (B) Immature RBCs (C) Immature platelets (D) Immature lymphocytes
C
A leukocyte count will be falsely elevated by which of the following in the peripheral blood? (A) Spherocytes (B) Reticulocytes (C) Metarubricytes (D) Bands
B
A neutrophil in which cytoplasm is more basophilic than normal and contains vacuoles is also known as a (A) Band cell (B) Toxic neutrophil (C) Metamyelocyte (D) Hypersegmented neutrophil
D
A normal leukocyte count with an increase in immature PMNs that outnumber mature PMNs is (A) Reticulocytosis (B) Leukopenia (C) Regenerative left shift (D) Degenerative left shift
D
A normal leukocyte count with an increase in immature neutrophils that outnumber mature neutrophils is (A) Leukocytosis (B) Leukopenia (C) A regenerative left shift (D) A degenerative left shift
B
Döhle bodies are found in what type of blood cell? (A) Erythrocyte (B) Neutrophil (C) Platelet (D) Nucleated RBC
B
Eosinophilia is commonly seen with a (A) Bacterial infection (B) Parasitic infection (C) Viral infection (D) Hormonal infection
D
Eosinophils would most commonly be found in the (A) Liver (B) Spleen and greater omentum (C) Muscle bellies (D) Lining of the lung
A
Leukopenia is (A) A decrease in WBCs (B) An increase in WBCs (C) A bone marrow disease (D) A type of blood cancer
B
Lymphocytic leukemia is indicated by finding what cells in a peripheral blood smear? (A) Large lymphocytes (B) Lymphoblasts (C) Small lymphocytes (D) Plasma cells
C
Megakaryocytes are the precursor cell to (A) Metarubricytes (B) Polychromatic cells (C) Thrombocytes (D) Monocytes
B
Phagocytes are a type of (A) RBC (B) WBC (C) Platelet (D) Anitbody
D
Phagocytosis does not involve (A) Chemotaxis (B) Adherence (C) Ingestion (D) Antibiosis
D
Physical signs of hypocoagulation include all of the following, except (A) Petechiae or ecchymoses (B) Epistaxis (C) Hematuria (D) Thromboembolism
D
Physiological leukocytosis can be caused by (A) Bacterial infection (B) Parasitic infection (C) Toxemia (D) Excitement
D
Platelet clumping could possibly affect the (A) RDW (B) PCV (C) RBC (D) Manual WBC count
B
The dark - staining material in the nuclei of lymphocytes and neutrophils is called ______ (A) Leukopoietin (B) Chromatin (C) Mitochondria (D) Endoplasmic reticulum
B
The first phagocytes to respond to an infection are (A) Lymphocytes (B) Neutrophils (C) Monocytes (D) Eosinophils
D
The least common leukocyte found on a normal bovine differential count is a(n) (A) Neutrophil (B) Monocyte (C) Eosinophil (D) Basophil
D
The leukocyte most commonly associated with parasitic and allergic conditions is the (A) Neutrophil (B) Monocyte (C) Lymphocyte (D) Eosinophil
C
The main function of the eosinophil is (A) Phagocytosis (B) Autoimmune reaction (C) Allergic reaction (D) Immune response
A
The main function of the neutrophil is (A) Phagocytosis (B) Hypersensitivity reactions (C) Allergic reaction (D) Immune response
B
The precursor cell of a thrombocyte is (A) Thromboblast (B) Megakaryocyte (C) Metakaryocyte (D) Prothrombocyte
D
The total WBC count of a healthy adult dog ranges from (A) 1,000 to 3,000/ul (B) 30,000 to 50,000/ul (C) 4,000 to 8,000/ul (D) 6,000 to 17,000/ul
D
Toxic neutrophils may show large (A) Blue granules (B) Black granules (C) Red granules (D) Purple granules
B
Under the microscope you observe a leukocyte that you identify as an eosinophil. The eosinophil cytoplasm contains numerous rod-shaped granules. This blood sample is most likely from a healthy adult (A) Dog (B) Cat (C) Horse (D) Cow
C
What blood cell is also known as a PMN? (A) Basophil (B) Eosinophil (C) Neutrophil (D) Monocyte
D
What blood cell resembles the mast cell found in tissues? (A) Eosinophil (B) Reticulocyte (C) Neutrophil (D) Basophil
D
What causes dark granules called Dohle bodies in the cytoplasm of canine neutrophils? (A) Leukemia (B) Parasitic infection (C) Immaturity (D) Toxemia
D
What cell becomes a macrophage once it enters the tissues? (A) Plasma cell (B) Lymphocyte (C) Neutrophil (D) Monocyte
C
What cell is produced at a site other than bone marrow? (A) Erythrocyte (B) Neutrophils (C) Lymphocytes (D) Monocytes
C
What cells are phagocytic (A) Granulocytes (B) Lymphocytes (C) Neutrophils and macrophages (D) Macrophages and lymphocytes
B
What clotting disorder is stimulated by hypothyroidism ? (A) Hemophilia A (B) Von Willebrand Disease (C) Disseminated intravascular coagulation (D) Coumarin toxicity
C
What is indicated by a neutrophil with a nucleus with six lobes? (A) Toxemia (B) Female animal (C) Old cell (D) Normal cell
C
What is normally the most numerous leukocyte seen in bovine blood? (A) Monocyte (B) Neutrophil (C) Lymphocyte (D) Eosinophil
B
What is normally the most numerous leukocyte seen in canine blood? (A) Monocyte (B) Neuytrophil (C) Lymphocyte (D) Eosinophil
A
What is not seen in DIC? (A) Icterus (B) Hemorrhage (C) Thrombocytopenia (D) Prolonged activated clotting time
D
What is seen in a degenerative left shift? (A) Leukocytosis (B) No bands are present (C) Lymphocytes outnumber neutrophils (D) Bands outnumber mature neutrophils
C
What is the function of the megakaryocyte? (A) Phagocytosis (B) Produces granulocytes (C) Produces thrombocytes (D) Produces plasma cells
A
What is the half life of neutrophils in the peripheral blood of dogs? (A) 6 hours (B) 24 hours (C) 7 days (D) 120 days
C
What is the most immature cell in the granulocyte series? (A) Megakaryocyte (B) Leukoblast (C) Myeloblast (D) Bands
C
What lab test evaluates primary hemostasis? (A) Activated clotting time (B) Activated partial thromboplastin time (C) Buccal mucosal bleeding time (D) One-step prothrombin time
D
What nuclear characteristic is associated with the most immature stage of eosinophil maturation? (A) Segmentation (B) Hypersegmentation (C) Chromatin clumping (D) Nucleoli
B
What order of maturation is correct? (A) Myeloblast, myelocyte, promyelcyte, metamyelocyte (B) Myeloblast, promyelocyte, myelocyte, metamyelocyte (C) Promyelocyte, metamyelocyte, myelocyte, band (D) Promyelocyte, myelocyte, band, segmented neutrophil
C
What species has the largest eosinophil granules? (A) Bovine (B) Canine (C) Equine (D) Feline
C
What species normally has eosinophils with small, round,red-staining cytoplasmic granules (A) Feline (B) Canine (C) Bovine (D) Equine
D
What substance is the final product in the coagulation pathway? (A) Thrombin (B) Plasmin (C) Factor VII (D) Fibrin
A
What term indicates an abnormally high lymphocyte count? (A) Lymphocytosis (B) Leukosis (C) Lymphocytopenia (D) Lymphosarcoma
D
What test is used to confirm a diagnosis of warfarin (rodenticide) toxicity? (A) Thrombocyte count (B) Calcium level (C) One-step prothrombin time (D) Partial thromboplastin time
A
What two cell types can be counted using a Unopette and hemocytometer? (A) Leukocytes and thrombocytes (B) Epithelial cells and erythrocytes (C) Thrombocyte and epithelial cells (D) Monocytes and plasma cells
C
What way of reporting WBC differential results is most useful? (A) As percentages (B) As relative numbers (C) As absolute numbers (D) As decimal numbers
B
What would be considered a normal WBC count for a healthy adult horse? (A) 30 x 10^3/ul (B) 8 x 10^3/ul (C) 30 x 10^6/ul (D) 8 x 10^6/ul
D
When collecting blood for a coagulation profile, it is especially important to (A) Use a gray-top vacutainer (B) Analyze the sample immediately (C) Use EDTA as the anticoagulant (D) Minimize vascular trauma during venipuncture
D
When counting cells on a hemocytometer, what cells are not counted? (A) Those on the top and bottom borders (B) Those on the left and right borders (C) Those on the left and top borders (D) Those on the right and bottom borders
D
When performing a CBC, a stained blood film will not allow you to evaluate the morphology of (A) Platelets (B) Small lymphocytes (C) Large lymphocytes (D) Macrophages
B
Where is the storage pool of granulocytes found? (A) Pancreas (B) Bone marrow (C) Liver (D) Capillaries
C
Where on the blood smear would you select to start your WBC differential? (A) Thickest area (B) Feathered edge (C) Monocellular layer (D) Thinnest area
A
Which blood cell can have vacuoles in its cytoplasm when seen in peripheral blood from a healthy animat? (A) Monocyte (B) Lymphocyte (C) Neutrophil (D) Thrombocyte
C
Which leukocyte count is in the normal reference range for a dog, cat, cow, or horse? (A) 35,000/uL (B) 5,750,000/uL (C) 7,500/uL (D) 272,000/uL
C
Which of the following cells has cytoplasmic granules that stain blue to blue-black and gray-blue cytoplasm, often with small vacuoles? (A) Neutrophil (B) Small lymphocyte (C) Basophil (D) Eosinophil
B
Which of the following cells has high nuclear-cytoplasm ratio; coarse, clumped, dark staining chromatin; and a sky blue cytoplasm? (A) Neutrophil (B) Small lymphocyte (C) Basophil (D) Eosinophil
C
Which of the following cells is usually associated with a chronic infection or inflammation? (A) Lymphocytes (B) Neutrophils (C) Monocytes (D) Eosinophils
A
Which of the following is correct when describing a large lymphocye? (A) It has the same function as a small lymphocyte (B) Its primary function is phagocytosis (C) It has a small amount of cytoplasm (D) Its nucleus stains dark blue with Wright's stain
D
Which of the following is not part of a stress leukogram? (A) Leukocytosis (B) Neutrophilia (C) Monocytosis (D) Eosinophilia
B
Which of the following is the least common granulocyte seen in the peripheral blood of a healthy adult cow? (A) Monocyte (B) Basophil (C) Eosinophil (D) Metarubricyte
C
Which one of thesee would not affect a manual WBC count? (A) Condenser in the farthest "up" position (B) Length of time that the hemocytometer has been loaded (C) Objective lens used (D) Mini clots in the blood
B
Which pair are both agranulocytes? (A) Monocytes and neutrophils (B) Lymphocytes and monocytes (C) Eosinophils and basophils (D) Lymphocytes and eosinophils
B
Which squares of the Neubauer hemocytom eter are used to count platelets? A) All nine large squares (B) All 25 small squares of the central primary square (C) Four small corner squares and the small central square of the central primary square (D) For small squares of the central primary square
A
Which squares of the Neubauer hemocytometer are used to count leukocytes? A) All nine large squares (B) All 25 small squares of the central primary square (C) Four small corner squares and the small central square of the central primary square (D) For small squares of the central primary square
C
Which statement is true regarding circulating leukocytes in a healthy adult cow? (A) Always decrease in # during infections (B) Always decrease in # during inflammations (C) Always include more than one cell type (D) Always are phagocytic
B
Basophils share characteristics with what tissue cell? (A) Macrophage (B) Mast cell (C) Phagocyte (D) Plasma cell
D
A Döhle body is identified with the Diff-Quik stain as (A) One small dark body on an erythrocyte membrane (B) A dark blue-staining protuberance on a neutrophil nucleus (C) Coarse. dark blue dots within an erythrocyte (D) A small, bluish-gray inclusion in a neutrophil cytoplasm
A
A QBC evaluates blood for (A) Quantitative buffy coat (B) Qualitiative buffy count (C) Quality blood count (D) Quantitative buffy cells
A
Coagulation tests would be useful for (A) Rodenticide poisoning (B) Thyroid function (C) Adrenal function (D) Ethylene glycol poisoning
C
On a CBC, all of the following findings could be expected in a patient with an infection, except (A) Neutrophilia (B) Leukocytosis (C) Narrow buffy coat (D) A left shift
B
Basophils are most commonly found in what tissues? (A) Eyeball (B) Near blood vessels (C) Avascular tissues (D) Bone marrow
B
A pleomorphic nucleus has (A) Many colors (B) Many shapes (C) Many nuclei (D) Undergone many divisions
C
A total leukocyte count can be falsely elevated by which of the following in the peripheral blood? (A) Spherocytes (B) Reticulocytes (C) Metarubricytes (D) Bands
C
A toxic neutrophil can be identified by all of the following characteristics, except (A) Cytoplasmic vacuolization (B) Cytoplasmic basophilia (C) Hypersegmentation (D) Dohle bodies
B
An intracellular parasite, which appears as a structure called morula, found in the cytoplasm of leukocytes, is (A) Babesia (B) Ehrlichia (C) Anaplasma (D) Theileria
D
At what stage in granulopoiesis do the specific or definitive granules first appear? (A) Metamyelocyte (B) Progranulocyte (C) Myeloblast (D) Myelocyte
D
Avian WBC counts can be determined indirectly by using what Unopette? (A) WBC (B) Platelet (C) RBC (D) Eosinophil
B
Fresh frozen plasma can be stored up to ________ and still contain clotting factors (A) 1 month (B) 12 months (C) 36 months (D) 60 months
B
Frozen fresh plasma must be separated and frozen within _____ hours to maintain all coagulation factors in normal concentrations (A) 2 (B) 8 (C) 12 (D) 6
C
Given a WBC count of 10,000 / μL and a relative value of 65 % neutrophils calculate the absolute value of neutrophils. (A) 65/ul (B) 650/ul (C) 6,500/ul (D) 65,000/ul
C
Heterophils in the avian species are the equivalent of the mammialian (A) Monocytes (B) Eosinophils (C) Neutrophils (D) Basophils
B
How does a band cell differ in appearance from a mature neutrophil? (A) The mature neutrophil is larger (B) The band nucleus has smooth, parallel sides (C) The band cytoplasm does not contain granules (D) The mature neutrophil has bluer cytoplasm
A
If eosinophil Unopettes are available, they can be used to indirectly determine the total count of avian (A) WBCs (B) RBCs (C) Platelets (D) Heterophils
D
In addition to birds, which one of the following animals also has WBCs called heterophils? (A) Llamas (B) Potbellied pigs (C) Ferrets (D) Reptiles
C
In healthy adult horses, the ratio of circulating neutrophils and marginated neutrophils is (A) 80:20 (B) 70:30 (C) 50:50 (D) 25:75
D
In what tissue would you normally expect to find the least number of eosinophils? (A) Skin (B) Lung (C) Small intestine (D) Lymph node
B
In which of these would you expect to find a predominance of lymphocytes on the differential WBC count? (A) Garfield (B) Billy Goat Gruff (C) Tweety Bird (D) Lassie
C
Monocytes typically have (A) Segmented nuclei (B) Band-shaped nuclei (C) Lobular nuclei (D) No nuclei
B
Sodium citrate is used for coagulation tests because it chelates calcium, allowing the coagulation process to be easily reversed by addition of (A) Thrombin (B) Ionized calcium (C) Prothrombin (D) Fibrinogen
A
Secondary hemostasis refers to (A) The coagulation cascade (B) Vascular spasm (C) Clot lysis (D) Platelet plug formation
A
Smudge cells are (A) Created while spreading blood for making a blood smear (B) Seen with Papanicolaou stains only (C) Created during blood smear staining process (D) Specific to species with nucleated RBCs only
D
The Unopette system for counting WBCs uses what diluent? (A) 0.85% saline (B) Distilled water (C) 9% hydrochloric acid (D) 1% ammonium oxalate
D
The abbreviation "seg" refers to to what blood cell? (A) Lymphocyte (B) Monocyte (C) Band neutrophil (D) Neutrophil
B
The bone marrow is not a major site of production for what cell type? (A) Erythrocytes (B) Lymphocytes (C) Neutrophils (D) Eosinophils
