19.4 - 19.6 : platelets, hemostasis, and blood typing
Which of the following substances does not inhibit coagulation?
prothrombin
Which of the following blood types is considered the universal recipient?
AB+
A sample reacts with anti-A and anti-B antibodies, but it does not react with anti-Rh antibodies. What is the sample's blood type?
AB-
Carbohydrate groups on the surfaces of erythrocytes determine blood type and are known as __________.
antigens
The ABO blood group is based on which antigen(s)?
antigens A & B
Which of the following characteristics do platelets have?
capable of oxidative catabolism
Which of the following events must occur first during hemostasis?
formation of thrombin
Which of the following blood types is compatible with B- during a transfusion?
O-
What is the functional consequence of vascular spasms during hemostasis?
Vascular spasms decrease blood vessel diameter to limit blood loss.
Select the appropriate pathway for the steps of hemostasis.
Vascular spasms, platelet plug formation, coagulation, clot retraction, and thrombolysis
Which of the following antibodies does a person with type B+ blood have in their plasma?
anti-A antibodies
Which of the following pairs of terms can be used interchangeably?
antibody & agglutinin
What ions are necessary for both the intrinsic and extrinsic pathways of the coagulation cascade?
calcium ions
Fibrin converts the soft, liquid platelet plug into a more solid mass by the process of ______________.
coagulation
Some rat poisons contain a toxin that blocks the liver's ability to use vitamin K. Animals that consume this poison would have problems with __________.
coagulation
What event initiates the intrinsic or contact pathway of coagulation?
factor XII contacts exposed collagen fibers
What process does agglutination promote?
hemolysis
What clotting disorder results from an inadequate amount of the Christmas factor (IX)?
hemophilia B
What process involves a series of events that minimizes the amount of blood lost from an injured blood vessel?
hemostasis
Platelets are cell fragments formed from __________.
megakaryocytes
Hemostasis is mediated by which of the following formed elements?
platelets
What enzyme coverts fibrinogen to fibrin?
thrombin
What process dissolves a blood clot?
thrombolysis
What condition results in the formation of an inappropriate blood clot?
thrombosis
What vitamin is necessary for certain clotting factors to operate during coagulation?
vitamin K
What chemical is produced by endothelial cells at the site of injury during the first step of platelet plug formation?
von Willebrand factor (vWF)
What is the average lifespan of a platelet?
7-10 days
Which antigens does a person with blood type A- have on the surface of his or her erythrocytes?
A antigens
Which of the following blood types would agglutinate if donated to a person with blood type A+?
B-
What is another name for the Rh antigen?
D antigen
