ALL QUIZZES

When 1,000 donors were tested, 75% were positive for C and 25% were negative for C; the gene frequency of

0.5

What is meant by the term autosomal?

A trait that is not carried on the sex chromosomes

In order to maintain ATP levels in stored blood, ______________ can be added to CPD to extend the shelf-life of stored RBCs from 21 days to 35 days. This new preservative is designated as CPDA-1.

Adenine and glucose

How is it genetically possible for a child to type Rh-negative?

Both parents are Dd

All of the following processes occur in replication, except:

DNA polymerase acts on the 5' to 3' parent strand to produce an anticomplementary duplicate strand.

Which change (mutation) is incapable of reverting back to the original phenotype?

Deletion type of genetics

What cryoprotective agent is added to red blood cells upon freezing?

glycerol

Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?

glycolysis

What is the normal life span of an RBC?

120 days

One of the most important controls of hemoglobin's affinity for oxygen is:

2,3-diphosphoglycerate (2,3-DPG)

If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?

20C - 24C

In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues when PO2 averages 40 mm Hg?

25%

Methods to isolate intact DNA in order for it to be studied include all of the following except:

Heat treatments

The ABO blood groups were discovered in 1901 by whom?

Karl Landsteiner

Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?

Luebering-Rapoport Shunt

What does the term autologous transfusion refer to?

An individual donating blood for his or her own transfusion

All of the following biochemical changes are associated with loss of red blood cell viability upon storage except:

Increased ATP level

In the MN blood group system, a person who inherits an "M" allele and an "N" allele expresses both M and N antigens on the RBCs. Which of the following is true?

M and N are codominant alleles

What factors are known to influence platelet metabolism and function?

Storage temp, initial pH, and platelet count.

A rare unit of blood became outdated 48 hours ago but is needed for a patient. Which of the following concepts applies to this situation?

The blood could be rejuvenated with Rejuvesol, washed, and given immediately to the patient

A unit of blood was returned to the blood bank before it was spiked. Apparently the patient's IV failed. The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most accurate?

Unit of blood must be transfused within 4 hours or be discarded at the end of that time

A father carries the Xga trait and passes it on to all of his daughters but none of his sons. What type of inheritance does this represent

X-linked dominant

A gene, such as the O gene, that produces no detectable product is called:

an amorph

Which of the following best describes the process of mitosis?

cell division that produces two daughter cells having the same number of chromosomes as the parent

In Mendel's law of separation, the first-filial generation is:

heterozygous

When an individual is said to have blood group A, it refers to the individual's:

phenotype

All of the following are included in transcription except:

RNA polymerase II binds to a promoter

How is RNA different from DNA?

RNA usually exists as a single strand and incorporates Uracil. Ribose is substituted for deoxyribose

What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs of alkalosis?

Shift to the left

Which of the following best describes classical genetics?

Transmission of characteristics from parents to offspring