ASCP MLT Exam
VIII, IX, XI, XII, PK, HMWK
Intrinsic pathway
cystic fibrosis
Iontophoresis is a technique used in the diagnosis of
resistant
Jk(a-b-) red cells are __________ to lysis in 2 M urea
VP +
Klebsiella, Enterobacter, Serratia
HHMM
LD 3
Alder-Reilly
Large, darkly staining cytoplasmic granules composed of partially digested mucopolysaccharides
Spleen
Last resort treatment of ITP is removal of
Cold agglutinins
Least likely to interfere with hemoglobin measurements
Kappa or lambda
Light chains can be comprised of
Apoenzyme
Portion of enzyme separated from its cofactor
acetylsalicylic acid
Reye's syndrome
37C
Rh antibodies react best at
Diffuse cutaneous scleroderma
Scl-70+
Dohle bodies
Seen in severe infections and burns
Candida dubliniensis
Seen in thrush in aids patients
blue black
Starch stains ______________________ with iodine
hemoglobinopathy
Substitution of an amino acid in the hemoglobin chain
20-24C
The proper storage requirements for granulocyte concentrates is
budding
The stage of viral replication where the envelope is being acquired and the HIV is leaving the host cell is known as
1-2 minute break
The suggested time for a break after 30 minutes of computer use is
teardrop
These cells are associated with myelofibrosis
ALT
This test is used in the evaluation of hepatic disease
Francisella tularensis
Tiny, weak staining, gram negative coccobacilli
45%
Transferrin level that indicates to investigate further for hereditary hemochromatosis
Non-nucleated red blood cells
When performing a bone marrow analysis, which cell type is not included in the differential?
Liver
Where does the first hydroxylation of vitamin D occur?
Kidneys
Where does the second hydroxylation of vitamin D occur?
haptoglobin
Which blood level will decrease during intravascular hemolysis?
Arbitrary primed
Which derivative of PCR testing uses short primers not specifically complementary to a particular sequence of a target DNA?
hepatitis
Which infectious agent represents the greates risk to the laboratory worker?
transcription-mediated amplification
Which modified PCR technique or other method of amplification is used to detect Mycobacterium tuberculosis?
FISH
Which molecular method uses fluorescent probes to evaluate genes and/or DNA sequences on chromosomes?
aldolase
Which of the following enzymes is associated with conditions affecting skeletal muscles?
pancreatitis
Which of the following is considered a cause of hypomagnesemia?
Nasopharyngeal swab
Which of the following is the most suitable specimen for the isolation of Bordetella pertussis?
fructosamine
Which of the following methods for long-term diabetic monitoring is recommended for patients with sickle cell anemia?
proteins
Which of the following types od molecules is MOST LIKELY to be antigenic/immunogenic? nucleic acids carbohydrates lipids proteins
malaria
Which of the following viruses or diseases is screened for in blood donors only using questions asked during the donor screening and selection process?
TH2
Which subset of effector lymphs is predominately responsible for regulation of antibody production?
Immunoelectrophoresis
Which test confirms the presence of Bence-Jones proteinuria?
Troponin T
Which troponin protein binds the troponin complex to tropomyosin?
CEA
Which tumor marker is used for colorectal cancer?
CK-MB and myoglobin
Which two of the following biomarkers are not specific to cardiac muscle and may be elevated in patients with injury to muscle other than cardiac muscle?
Anti-A,B
Which type of antibody can cause HDFN in any pregnancy (first or subsequent), but is usually limited to less severe symptoms?
LDL
Which type of lipoprotein transports the MAJORITY of cholesterol to cells for steroid hormone synthesis or cell membrane incorporation?
Ionized calcium
Would be decreased due to delay in centrifugation
30 ml whole blood
a full 300 ug dose on RhIg provides protection for
8 weeks
accepted interval between whole blood donations
CIN
agar selective for Yersinia entercolitica
EBV virus
asymptomatic, >20% reactive lymphs
aminoglycosides
-mycins
Calcium
8-Hydroxyquinoline and CPC reagent is commonly used in the determination of
Color Doppler
BEST correlates with the severity of HDFN
1:10
Best dilution for slightly hazy CSF
dark field microscopy
Best suited for direct examination of infectious agent of syphilis
shaggy star
Candida parapsilosis
rosette clusters
Cardiobacterium hominis
indole pos
Chryseobacterium spp.
Treponemes
Direct examination can be performed by darkfield microscopy examination
Diphyllobothrium latum
Double genital pores emanating from each of the proglottids
VII, III
Extrinsic pathway
Leucine
Found in maple syrup urine disease
Necator americanus
Hookworm, long buccal cavity in rhabditiform
room temperature
How should a PT be stored until it is picked up by a courier?
Scopulariopsis
Hyaline mold that produces conidia in chains
Magnesium
Important metallic activator of alkaline phosphatase and creatine kinase
HbA
In the heterozygous state of HbS, sickle cell trait, which of the following hemoglobins appear in combination with HbS?
Obstructive jaundice
Increased alkaline phosphatase is found in
LDL-C
Increased level of ___________ indicates an increased risk of cardiovascular disease
Pneumocystis jiroveci
Increased risk of contracting this unusual form of pneumonia in AIDS patients
thrombosis
Obstruction of a blood vessel caused by a stationary blood clot is called
Acute glomerulonephritis
Oliguria is usually correlated with
Leb
Only this antigen adsorbs onto the red cells of adults
mariner's wheel
Paracoccidioides brasiliensis
carcinoid tumor
A markedly elevated 5-HIAA determination is presumptive evidence for
4 weeks
A potential donor who has received a German measles (rubella) vaccine is deferred for
HDN
A spectrophotometric scan of amniotic fluid may be valuable in the determination of which of the following conditions?
urine, serum, and whole blood
Acetest can be used to test for ketones in
HbS polymerization
Acid ph, dehydration, increased level of 2,3-DPG increases risk of
Lavender
Acinetobacter baumannii are ________________ on MAC agar
18-30 hours
After an AMI myoglobin levels will rise within 3 hours and peak at 8-12 hours. When will they return to normal?
Mild proteinuria
All of the following are urinalysis findings associated with nephrotic syndrome except: Oval fat bodies Fatty and waxy casts Renal tubular epithelial cells Mild proteinuria
I, II, V, X, XIII
All pathways
acute hemolytic transfusion reactions
Antibodies directed against granulocyte antigens have been implicated for all of the following except
IgG
Antibody class of paroxysmal cold hemoglobinuria
Haptoglobin
Appears in the alpha-2-globulin band
5-7
Approximately how many doses are required to obtain a steady state oscillation allowing for peak and trough levels of be evaluated?
Flavus
Aspergillus species that is granular to wooly with some shade of yellow or yellow-green
Thromboxane A2
Aspirin ingestion prevents the synthesis of this signaling molecule in the platelet
Burkholderia cepacia
Motile with polar tufts of flagella and can produce yellow pigment
CD2, 11b, 16
NK cells express
Anti-HBc
Necessary test to detect patients in the window period of a hepatitis B infection
Flavobacterium
Needs xylene extraction and Ehrlich's reagent for indole test
sucrose
Not considered a reducing sugar
Lewis
Not expressed, or weakly expressed on cord blood cells
lower, higher
Potassium, calcium, and total protein are ___________ in capillary specimens, where glucose is typically _______________ than in venous blood.
Kidd
Proteolytic enzyme techniques may be useful in identifying which of the following antigen groups?
zero order
Reaction depends only on enzyme concentration
polychromatic normoblast
Red cells begin forming enough hemoglobin to be visualizes on a wright stained bone marrow aspirate smear
primary myelofibrosis
The JAK2 mutation is seen in
flow cytometry
The MOST reliable method for determining the appropriate dosage of Rh immune globulin to give to an identified Rh immune globulin candidate after delivery is
gp41 or gp160
The Western Blot for HIV-1 infection identification looks for HIV p24 and what other two protein bands to confirm HIV-1 infection?
HBeAg
The antigen marker most closely associated with transmission of HBV infections is
Health hazard
The blue section of fire diamond means
B lymphs
The causative agent of infectious mono attaches to a receptor on which of the following cells?
sporothrix schenckii
The dimorphic fungi that may produce black, yeast-like colonies after prolonged incubation at 37C is
acetoacetic acid
The ketone component that is measured by the nitroprusside reaction
Pentatrichomonas hominis
Trophozoite is the only morphologic form in the life cycle of
Mixed connective tissue disease
U1RNP+
meat diet
Urine test strip positive for blood may indicate all except
Rabbit erythrocyte stroma
What absorption technique removes cold (IgM) antibodies, particuarly anti-I specificities?
NAD+
What coenzyme does LD use when converting lactate to pyruvate?
coomassie brilliant blue 250
What dye-binding method uses an increase of absorbance at 595 nm to determine the total protein concentration of the specimen?
extravascular
What form of hemolysis is seen in hereditary spherocytosis?
CDe/ce
What genotype is found with the highest frequency in caucasian population?
18-23 days; it binds with neonatal Fc receptor
What is the half-life of IgG? Why is the duration of the half-life significant?
myocardial ischemia
What is the term used to describe inadequate blood supply that decreases availability of oxygen to the myocardium?
1.5-2 mmol/L
What is the toxic level of lithium?
interferon-gamma release assays
What method is used to identify prior exposure to Mycobacterium tuberculosis?
platelet neutralization test
What test should be performed to determine if the patient has lupus anticoagulant?
monitoring course of treatment
benefits of RPR or VDRL tests
glucuronic acid
conjugates bilirubin
Sporothrix
daisy-like clusters produced from the tips of straight, delicate conidiosphores
aspirin
does not cause abnormal TT
reptilase
evaluate the adequacy of fibrinogen in heparinized patients
absence
high specificity means to accurately identify the _________________ of disease
brown/black urine
homogentisic acid
Hepatocellular carcinoma
increased AFP in adults
fibrinogen
most responsible for increasing the sed rate
CSF3R
mutation in chronic neutrophilic leukemia
exserohilum
nipple-like protrusion
speckled
no staining in metaphase mitotic cells
Rickettsia
obligate intracellular parasite
0.04 to 0.08
pH alteration of normal blood in a closed vessel standing at 37C for 1 hour is approximately
Bordatella pertussis
potato-blood-glycerol agar
LD50
the dose of drug in which 50% of the individuals will result in mortality
adenine and guanine
uric acid is the final breakdown product of what two purines?
Pulsed field electrophoresis
used to separate larger DNA fragments
diabetes
uses microalbuminuria to monitor
