Be able to match the disease with the microbe that causes it

Staph aureus

(gram + cocci) biols, toxic shock, superantigen, exfoliative toxin (scaled skin syndrome) MRSA --> Methicillin resistant , horizontal gene transfer, evolved in hospitals, reistant to everything except vancomycin

Strept. Pyogenes

(gram +cocci) GAS, necrotizing fascitis, flesh eating, primary cause, virulence factors

pseudomonas aerugnosa

Grod infects cystic fibrosis patients fevers, chills, cough, chest pain

Flea bite inhaled

pneumonic plague highly contagious, type 3 secretion systems virulence factors inhibit phagocytosis

Which microbial diseases are transmitted by ticks

Borrelia burgdoferi: Lyme disease, tick ixodes, spirochete, antigenic variation

Clostridium Botulinum

CNS infection Botulin toxin, botox, anaerobe, canned food, toxin ingested, prevents muscle movement, blocks Ach release

Clostridium Tetani

CNS infection tetanus tocin, anaerobe, puncture wounds, exotoxin tetanospasmin blocks GABA release, excessive nerve signaling to muscle, uncontrollable lethal spasms

Meningitis

CNS infection viral or bacterial strep pneumonia, group B strep., Haemohilus influenza Neisseria meningitides (meningococcal meningitis)-thick LPS endotoxin, type 4 pili, capillary to CSF

Salmonella, shigella, "enteroinvasive" ecoli (EIEC)

gastroenteritis entbacterial toxin producing strains Type 3 secretion EIEC and shigella produce shiga toxin outside epithelial cells-Ecoli-EHEC(O157:H7) ETEC, EAEC-secrete Tir into host cells, attachment and lesions, entero-homorrhagic, tocigenic aggregative

Clostridium difficile

gastrointestinal disease misuse of antibitoics on viruses

Flea bite introduction through bloodstream

septicemic plague

HCV

Hep C flavivirus ss+RNA

HBV

Hep B Hepadnavirus dsDNA

CMV disease

Cytomegalovirus CMV, dsDNA

Strep Pneumonia

G+ diplococcus fevers, chills, cough, chest pain

Norovirus

Gastroenteritis Norwalk virus highly infectious lethal dehydration

HAV

Hep A picornnavirus ss-RNA

Legionnaires disease

Legionella pneumophia, G-rod, fever, chest pain, chills cough, muscle pain, vomiting, diarrhea

Leptospira interrogans

Leptospirosis, spirchete, burrowing motility, vaccination for animals

Which microbial diseases are transmitted by mosquitos

Mosquito born encephalitis viruses: west nile, eastern equine, st louis

Tuberculosis

Mycobacterium tuberculosis, acid fast bacillus fever, chilles, cugh, bloody sputum, fatigue, weight loss

Rubeolla

Paramycovirsus, SSRNA-, measles, severe disease, fever, conjuctivitis, cough, rash

Which microbial disease are transmitted by fleas

Plague- yersinia pestis

RSV disease

Respiratory syncytial virus RSV, ssRNA-

Severe acute respiratory syndrome

SARS virus, ssRNA+

Vibrio Vulnificus

Vibriosis G-curved rod cytolysin, capsule

Rabies

Viral CNS enveloped virus- ssRNA genome, saliva of animal bite, long incubation period

Chlamydophilia pneumonia

associated with cardio disease, fever, sore throat, chest pain, runny nose

Whopping cough

brdetella pertusis, G-coccobacillus, fever, runny nose, sneezing, violent cough foolwed by whoop

Brucella abortus

brucellosis, G- rod, intracellular growth in monocytes

Flea bite introduction through lymph nodes

bubonic plague G- rod, intracellular growth type 3 secretion

Diptheria

corynebacterium diptheriae, G+ rod, tracheal pseudomembrane

Adenovirus

dsDNA

Varicella zoster

dsDNA, herpes virsus, chickenpox-generalized discolored lesions/shingles-pain and lesions, usually on trunk in adults

variola

dsDNA, smollpox, variola major, raised, crusted skin rash, highly contagious

Rickettsia prowazekii

epidemic typhus, obligate intracellular growth, escapes phagosome, G-rode

Rotavirus

gastroenteritis dsRNA reovirus, most common cause of stomach flu

Prion CNS

mad cow disease

Walking pneumonia

mycoplasma pneumonia (wall-less microbe) fever, sore throat, nonproductive cough, chills

Warts

papillomavirus, dsDNA, rapid growth of skin cells

Influenza and parainfluenza viruses

ssRNA(-)/segmented

Rubella

togavirsus, ssRNA+, german measels, pimply rash, mild disease unless congenital

Francisella tularensis

tularemia G-rod intracellular

Salmonella typhi and S. cholerasuis

typhoid fever, G-rod, Type 3 secretion, intracellular growth, antigen capsule