Be able to match the disease with the microbe that causes it
Staph aureus
(gram + cocci) biols, toxic shock, superantigen, exfoliative toxin (scaled skin syndrome) MRSA --> Methicillin resistant , horizontal gene transfer, evolved in hospitals, reistant to everything except vancomycin
Strept. Pyogenes
(gram +cocci) GAS, necrotizing fascitis, flesh eating, primary cause, virulence factors
pseudomonas aerugnosa
Grod infects cystic fibrosis patients fevers, chills, cough, chest pain
Flea bite inhaled
pneumonic plague highly contagious, type 3 secretion systems virulence factors inhibit phagocytosis
Which microbial diseases are transmitted by ticks
Borrelia burgdoferi: Lyme disease, tick ixodes, spirochete, antigenic variation
Clostridium Botulinum
CNS infection Botulin toxin, botox, anaerobe, canned food, toxin ingested, prevents muscle movement, blocks Ach release
Clostridium Tetani
CNS infection tetanus tocin, anaerobe, puncture wounds, exotoxin tetanospasmin blocks GABA release, excessive nerve signaling to muscle, uncontrollable lethal spasms
Meningitis
CNS infection viral or bacterial strep pneumonia, group B strep., Haemohilus influenza Neisseria meningitides (meningococcal meningitis)-thick LPS endotoxin, type 4 pili, capillary to CSF
Salmonella, shigella, "enteroinvasive" ecoli (EIEC)
gastroenteritis entbacterial toxin producing strains Type 3 secretion EIEC and shigella produce shiga toxin outside epithelial cells-Ecoli-EHEC(O157:H7) ETEC, EAEC-secrete Tir into host cells, attachment and lesions, entero-homorrhagic, tocigenic aggregative
Clostridium difficile
gastrointestinal disease misuse of antibitoics on viruses
Flea bite introduction through bloodstream
septicemic plague
HCV
Hep C flavivirus ss+RNA
HBV
Hep B Hepadnavirus dsDNA
CMV disease
Cytomegalovirus CMV, dsDNA
Strep Pneumonia
G+ diplococcus fevers, chills, cough, chest pain
Norovirus
Gastroenteritis Norwalk virus highly infectious lethal dehydration
HAV
Hep A picornnavirus ss-RNA
Legionnaires disease
Legionella pneumophia, G-rod, fever, chest pain, chills cough, muscle pain, vomiting, diarrhea
Leptospira interrogans
Leptospirosis, spirchete, burrowing motility, vaccination for animals
Which microbial diseases are transmitted by mosquitos
Mosquito born encephalitis viruses: west nile, eastern equine, st louis
Tuberculosis
Mycobacterium tuberculosis, acid fast bacillus fever, chilles, cugh, bloody sputum, fatigue, weight loss
Rubeolla
Paramycovirsus, SSRNA-, measles, severe disease, fever, conjuctivitis, cough, rash
Which microbial disease are transmitted by fleas
Plague- yersinia pestis
RSV disease
Respiratory syncytial virus RSV, ssRNA-
Severe acute respiratory syndrome
SARS virus, ssRNA+
Vibrio Vulnificus
Vibriosis G-curved rod cytolysin, capsule
Rabies
Viral CNS enveloped virus- ssRNA genome, saliva of animal bite, long incubation period
Chlamydophilia pneumonia
associated with cardio disease, fever, sore throat, chest pain, runny nose
Whopping cough
brdetella pertusis, G-coccobacillus, fever, runny nose, sneezing, violent cough foolwed by whoop
Brucella abortus
brucellosis, G- rod, intracellular growth in monocytes
Flea bite introduction through lymph nodes
bubonic plague G- rod, intracellular growth type 3 secretion
Diptheria
corynebacterium diptheriae, G+ rod, tracheal pseudomembrane
Adenovirus
dsDNA
Varicella zoster
dsDNA, herpes virsus, chickenpox-generalized discolored lesions/shingles-pain and lesions, usually on trunk in adults
variola
dsDNA, smollpox, variola major, raised, crusted skin rash, highly contagious
Rickettsia prowazekii
epidemic typhus, obligate intracellular growth, escapes phagosome, G-rode
Rotavirus
gastroenteritis dsRNA reovirus, most common cause of stomach flu
Prion CNS
mad cow disease
Walking pneumonia
mycoplasma pneumonia (wall-less microbe) fever, sore throat, nonproductive cough, chills
Warts
papillomavirus, dsDNA, rapid growth of skin cells
Influenza and parainfluenza viruses
ssRNA(-)/segmented
Rubella
togavirsus, ssRNA+, german measels, pimply rash, mild disease unless congenital
Francisella tularensis
tularemia G-rod intracellular
Salmonella typhi and S. cholerasuis
typhoid fever, G-rod, Type 3 secretion, intracellular growth, antigen capsule