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Heterozygous

A diploid organism is heterozygous at a gene locus when its cells contain two different alleles of a gene. The cell or organism is called a heterozygote specifically for the allele in question, therefore, heterozygosity refers to a specific genotype.

Gene

A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. -Glossary. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits.

Carrier

A genetic carrier (or just carrier), is a person or other organism that has inherited a recessive allele for a genetic trait or mutation but does not display that trait or show symptoms of the disease.

Transgenic Organism

A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques (i.e. genetically engineered organism).

Genotype

A genotype is an individual's collection of genes. The term also can refer to the two alleles inherited for a particular gene. The genotype is expressed when the information encoded in the gene's' DNA is used to make protein and RNA molecules.

Monohybrid

A monohybrid cross is a mating between two individuals with different alleles at one genetic locus of interest. The character(s) being studied in a monohybrid cross are governed by two or multiple alleles for a single locus.

Pedigree

A pedigree chart is a diagram that shows the occurrence and appearance or phenotypes of a particular gene or organism and its ancestors from one generation to the next, most commonly humans, show dogs, and race horses.

Phenotype

A phenotype (from Greek phainein, meaning "to show", and typos, meaning "type") is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, phenology, behavior, and products of behavior (such as a bird's nest).

Polygenic Trait

A polygenic trait is one whose phenotype is influenced by more than one gene. Traits that display a continuous distribution, such as height or skin color, are polygenic.

Trait

A trait is a specific characteristic of an organism. Traits can be determined by genes or the environment, or more commonly by interactions between them. The genetic contribution to a trait is called the genotype. The outward expression of the genotype is called the phenotype.

F1

An F1 hybrid (or filial 1 hybrid) is the first filial generation of offspring of distinctly different parental types. F1 hybrids are used in genetics, and in selective breeding, where it may appear as F1 crossbreed.

Allele

An allele is a variant form of a gene. Some genes have a variety of different forms, which are located at the same position, or genetic locus, on a chromosome. Humans are called diploid organisms because they have two alleles at each genetic locus, with one allele inherited from each parent.

Segregation

As chromosomes separate into different gametes during meiosis, the two different alleles for a particular gene also segregate so that each gamete acquires one of the two alleles.

True

Breeding - A true breeding organism, sometimes also called a purebred, is an organism that always passes down certain phenotypic traits (i.e. physically expressed traits) to its offspring.

CoDominance

Codominance is a relationship between two versions of a gene. Individuals receive one version of a gene, called an allele, from each parent. If the alleles are different, the dominant allele usually will be expressed, while the effect of the other allele, called recessive, is masked.

Dihybrid

Dihybrid cross is a cross between two different lines (varieties, strains) that differ in two observed traits. In the Mendelian sense, between the alleles of both these loci there is a relationship of complete dominance - recessive.

Dominant

Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus. The first allele is dominant and the second allele is recessive.

Electrophoresis

Electrophoresis is a technique used in laboratories in order to separate macromolecules based on size. The technique applies a negative charge so proteins move towards a positive charge. This is used for both DNA and RNA analysis.

Fertilization

Fertilization (also known as conception, fecundation, syngamy and impregnation) is the fusion of gametes to initiate the development of a new individual organism. In animals, the process involves the fusion of an ovum with a sperm, which first creates a zygote and then leads to the development of an embryo.

Genetics

Genetics is the study of genes, heredity, and genetic variation in living organisms. It is generally considered a field of biology, but it intersects frequently with many of the life sciences and is strongly linked with the study of information systems.

Homozygous

Homozygous is a word that refers to a particular gene that has identical alleles on both homologous chromosomes. It is referred to by two capital letters (XX) for a dominant trait, and two lowercase letters (xx) for a recessive trait.

Vector

In molecular cloning, a vector is a DNA molecule used as a vehicle to artificially carry foreign genetic material into another cell, where it can be replicated and/or expressed. A vector containing foreign DNA is termed recombinant DNA.

Incomplete Dominance

Incomplete dominance is a form of intermediate inheritance in which one allele for a specific trait is not completely expressed over its paired allele.

Sex

Linked Traits - In humans, red-green colorblindness is a recessive sex-linked trait. It is found on the X chromosome, not the Y. Because, males only have one X chromosome, they have a much greater chance of having red-green colorblindness. Females would have to be homozygous recessive in order to have red-green colorblindness.

Recessive

Recessive traits can be carried in a person's genes without appearing in that person. For example, a dark-haired person may have one gene for dark hair, which is a dominant trait, and one gene for light hair, which is recessive.

Restriction Enzyme

Restriction enzymes, also known as restriction endonucleases, are enzymes that cut a DNA molecule at a particular place. They are essential tools for recombinant DNA technology. The enzyme"scans" a DNA molecule, looking for a particular sequence, usually of four to six nucleotides.

Independent assortment

The Principle of Independent Assortment describes how different genes independently separate from one another when reproductive cells develop. Independent assortment of genes and their corresponding traits was first observed by Gregor Mendel in 1865 during his studies of genetics in pea plants.

Hybrid

The first meaning is the result of interbreeding between two animals or plants of different taxa. Hybrids between different species within the same genus are sometimes known as interspecific hybrids or crosses.Hybrids between different subspecies within a species are known as intra-specific hybrids.

F2

The second filial generation, which is comprised of offspring(s) resulting ... The F2 generation is the result of a cross between two F1

Gamete

a mature haploid male or female germ cell that is able to unite with another of the opposite sex in sexual reproduction to form a zygote.

Multiple Allele

multiple alleles Three or more alternative forms of a gene (alleles) that can occupy the same locus. However, only two of the alleles can be present in a single organism. For example, the ABO system of blood groups is controlled by three alleles, only two of which are present in an individual.


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