Cardiac Output
What AFFECTS preload?
- Total blood volume and volume distribution - Cardiac compliance - Myocardial contractility - Increase in afterload or ventricular impedence
Afterload is AFFECTED by what?
- Vasodilation/vasoconstriction - Valvular impedence - Atherosclerosis (turbulant vs laminar flow) - Blood volume and viscosity
What 3 factors INFLUENCE cardiac output?
1. Preload (Intravascular fluid volume) 2. Afterload (Vascular resistance) 3. Contractility of the heart
What is end systolic volume?
Amount of blood in the ventricles at the end of ventricular systole
What is the formula for cardiac output?
CO = HR x Stroke volume
What is cardiac output AFFECTED by?
Cardiac function and fluid status
The strength of the hearts contraction is known as what?
Contractility
Preload is INFLUENCED by what?
It is affected by the blood returning to the heart via pulmonary or systemic veins
What is myocardial tension caused by stretching before contraction?
Preload
Preload, Afterload and contractility affect what?
Stroke volume
What is end diastolic volume?
The amount of blood in the ventricle at the end of ventricular diastole - After the atrial kick
What is cardiac output?
The amount of blood pumped by the heart each minute (L/min)
What is stoke volume?
The amount of blood pumped with each heartbeat
What is afterload?
The resistance against which the heart must pump to get blood into the arteries
You need adequate cardiac output for what?
To perfuse organs and tissues
What is the average stroke volume in an adult?
~ 70mls