Ch 14 - Review Questions

True/False FFP, packed RBCs, platelets, or cryoprecipitate are used to treat DIC.

True

True/False Hemophilia is the most inherited coagulation disorder resulting in excessive bleeding.

True

True/False Parenteral/IV administration of vitamin K is avoided due to a possible anaphylactic reaction.

True

PT/INR, aPTT, D-dimer tests are elevated in which disorder? A - Hemophilia A B - DIC C - Von Willebrand disease D - Thrombocytopenia

B - DIC

Which disorder may be caused by trauma, malignancy, burns, shock, and abruptio placentae? A - Hemophilia A B - DIC C - Von Willebrand disease D - Thrombocytopenia

B - DIC

Which hemophilia type has a deficiency in factor IX? A - Hemophilia A B - Hemophilia B C - Relax with a cup of coffee/tea

B - Hemophilia B

Blood found in sputum is called? A - Epistaxis B - Hemoptysis C - Menorrhagia D - Hematemesis

B - Hemoptysis

Transitory thrombocytosis is due to? A - Hemorrhage B - Stress/physical exercise C - Splenectomy D - Polycythemia vera

B - Stress/physical exercise

What is it called when widened venules cause thread-like red lines or patterns on the skin, AKA spider veins? A - Petechiae B - Telangiectasia C - Purpura D - Bruises/ecchymosis

B - Telangiectasia

If a patient has a family history of bleeding disorders in both males and females, this is a clue for which disorder? A - Factor XIII deficiency B - Von Willebrand disease C - Hemophilia A or B D - Mild to severe deficiency of coagulation factors

B - Von Willebrand disease

Folate/B12 deficiency, radiation/chemotherapy, drugs, aplastic anemia, and bone marrow cancer causes thrombocytopenia through? A - Splenic sequestration B - Intravascular dilution of circulating platelets C - Decreased platelet survival D - Decreased platelet production

D - Decreased platelet production

PT/INR is a lab test used to assess what? A - Intrinsic pathway of coagulation B - Platelet count C - Platelet function D - Extrinsic pathway of coagulation

D - Extrinsic pathway of coagulation

True/False Platelet transfusions or whole/packed blood is NOT a viable treatment for hepatic disease.

False

The normal range for PT (PT/INR) is? A - 12 to 13 B - 8 to 10 C - 16 to 20 D - 11 to 14

D - 11 to 14

What should the goal for INR be for most disorders? A - 2.5 to 3.5 B - 4 to 5 C - 0.8 to 1.1 D - 2 to 3

D - 2 to 3

What can inadequate hemostasis lead to? A - Clotting disorders B - Anemia C - Leukocytosis D - Bleeding disorders

D - Bleeding disorders

What should the goal for INR be for patients with metal heart valves? A - 2.5 to 3.5 B - 4 to 5 C - 0.8 to 1.1 D - 2 to 3

A - 2.5 to 3.5

The normal range for an aPTT test is? A - 30 to 40 sec B - 60 to 70 sec C - 40 to 50 sec D - no idea

A - 30 to 40 sec

What can excessive hemostasis lead to? A - Clotting disorders B - Anemia C - Leukocytosis D - Bleeding disorders

A - Clotting disorders

Defects of the normal clotting mechanism is called? A - Coagulopathies B - Platelet disorders C - Hemophilia D - Thrombocytopenia

A - Coagulopathies

Occult or frank bleeding from the nose is called? A - Epistaxis B - Hemoptysis C - Menorrhagia D - Hematemesis

A - Epistaxis

What does a vitamin K deficiency result in? A - Excessive bleeding B - Excessive clotting C - Malnutrition D - Chronic hepatic disease

A - Excessive bleeding

A decrease in the synthesis of fibrinogen and factor V and XI along with impaired absorption of vitamin K results in what coagulopathy? A - Hepatic disease B - DIC C - Hemophilia A D - Hemophilia B

A - Hepatic disease

Which statement is true about disseminated intravascular coagulation (DIC)? A - It is both a bleeding and clotting disorder B - The acute form has more thrombotic episodes C - Fibrin split products are decreased D - Fibrinogen level is increased

A - It is both a bleeding and clotting disorder

What is it called when pinpoint, round red, brown, or purple spots appear on the skin in clusters, and may look like a rash, as a result of bleeding? A - Petechiae B - Telangiectasia C - Purpura D - Bruises/ecchymosis

A - Petechiae

PT/INR helps determine the use of which med? A - Warfarin B - Heparin C - Thrombolytics D - Aspirin

A - Warfarin

What is the normal range for INR? A - 2.5 to 3.5 B - 4 to 5 C - 0.8 to 1.1 D - 2 to 3

C - 0.8 to 1.1

Vitamin K deficiency causes bleeding and affects which baby? A - Premature B - Disabled C - Breast-fed D - Formula-fed

C - Breast-fed

Which is true regarding hemophilia A? A - Carried by a symptomatic female carrier B - AKA Christmas disease C - Caused by factor VIII deficiency D - It is an X-linked dominant disorder

C - Caused by factor VIII deficiency

Drugs, mechanical prosthetic heart valves, viral/bacterial infection, circulating immune complexes, increased destruction in the spleen, and disseminated intravascular coagulation causes thrombocytopenia through? A - Splenic sequestration B - Intravascular dilution of circulating platelets C - Decreased platelet survival D - Decreased platelet production

C - Decreased platelet survival

Melena or hematochezia is bleeding found in? A - Urine B - Vomit C - Feces D - Sputum

C - Feces

If a patient has a family history of bleeding disorders in males, this is a clue for which disorder? A - Factor XIII deficiency B - Von Willebrand disease C - Hemophilia A or B D - Mild to severe deficiency of coagulation factors

C - Hemophilia A or B

Excessive menstrual bleeding is know as? A - Epistaxis B - Hemoptysis C - Menorrhagia D - Hematemesis

C - Menorrhagia

Factors released by platelets contribute to hemostasis by enhancing what? A - Vasodilation B - Intrinsic pathway C - Platelet aggregation D - Fibrinolysis

C - Platelet aggregation

Thrombocytosis in response to hemorrhage, a disease process, or splenectomy is which type? A - Transitory B - Primary C - Secondary D - Dolphins are cool

C - Secondary

Which is an autosomal dominant disorder of factor VIII carrier protein and platelet dysfunction that causes excessive bleeding? A - Hemophilia A B - DIC C - Von Willebrand disease D - Thrombocytopenia

C - Von Willebrand disease

True/False Vitamin K deficiency may occur with malnutrition and malabsorption but does NOT occur with chronic hepatic disease, antibiotic therapy, or oral anticoagulation therapy.

False