exam two quick misses

oxazolidinones ADE

hematologic

vanco ADEs w/ IV therapy

histamine-mediated reaction, nephrotoxicity

IgE-mediated

hives

only stimulant taken at bedtime

jornay PM

alternative to the 2 drug combo of beta-lactam and macrolide for CAP

levo, moxi

standard of care for treating pregnant women w/ opioid use d/o

methadone (may need higher doses)

lipophilic

metronidazole

gram-negative w/ NO risk for pseudomonas

unasyn

aminopenicillins indications

upper/lower resp tract infection

methadone ADE

QT prolongation (monitor EKG)

macrolides ADEs

QT prolongation, hepatotoxicity

mix with 4 oz of water, take w/ food

fosfomycin

monobactam is ONLY

gram negative

glycopeptides, clindamycin, oxa are ONLY

gram positive

aminoglycosides ADEs

ototoxicity, nephrotoxicity, neuromuscular blockade

tetracyclines ADEs

photosensitivity, esophageal irritation

vanco IV trough

prior to 4th dose, 15-20

nitrofurantoin ADEs

pulm, hemolytic anemia

non-IgE-mediated

rash

baby heroin

seroquel

bactrim ADEs

sulfa allergy, hyperkalemia, rash, renal failure

gram-negative w/ risk for pseudomonas

zosyn

antistaphylococcal ADE

AAIN

atomoxetine metabolism

CYP

bactrim metabolism

CYP

clarithromycin/erythromycin metabolism

CYP (potent)

acamprosate contraindication

CrCl < 30

ceftaroline

MRSA

daptomycin NOT a good choice for

MRSA pneumonia

misuse of PO vanco can lead to

VRE

stimulants BBW

abuse potential, CV events

metronidazole DIs

alcohol, warfarin

PAE

aminoglycosides

narrow therapeutic window

aminoglycosides

poor tissue distribution

aminoglycosides

FQ DIs

antiarrhythmics, cation chelation

aminoglycosides have a synergistic effect w/

beta lactams and glycopeptides

direct observation not needed for

buprenorphine

poor man's cocaine

bupropion

seizure risk is a class effect

carbapenems

tetracyclines DIs

cation chelation

what can be used for sx associated with opioid withdrawal

clonidine

stimulants increase

dopamine and NE

pts w/ true beta lactam allergy

monobactam

avoid what alcohol use med in hepatic failure

naltrexone

REMS program

naltrexone IM

mu opioid receptor antagonists

naltrexone, naloxone

FQ ADEs

neurotoxicity, QT prolongation, tendon rupture

CAMs for ADHD

omega 3 and 6, ferrous sulfate

good 1st line for children w/ tic d/o

vyvanse

DIs w/ oritavancin

warfarin

bactrim DIs

warfarin

transdermal patch timing

wear up to 9 hrs, effects last 3 hrs after removed