exam two quick misses
oxazolidinones ADE
hematologic
vanco ADEs w/ IV therapy
histamine-mediated reaction, nephrotoxicity
IgE-mediated
hives
only stimulant taken at bedtime
jornay PM
alternative to the 2 drug combo of beta-lactam and macrolide for CAP
levo, moxi
standard of care for treating pregnant women w/ opioid use d/o
methadone (may need higher doses)
lipophilic
metronidazole
gram-negative w/ NO risk for pseudomonas
unasyn
aminopenicillins indications
upper/lower resp tract infection
methadone ADE
QT prolongation (monitor EKG)
macrolides ADEs
QT prolongation, hepatotoxicity
mix with 4 oz of water, take w/ food
fosfomycin
monobactam is ONLY
gram negative
glycopeptides, clindamycin, oxa are ONLY
gram positive
aminoglycosides ADEs
ototoxicity, nephrotoxicity, neuromuscular blockade
tetracyclines ADEs
photosensitivity, esophageal irritation
vanco IV trough
prior to 4th dose, 15-20
nitrofurantoin ADEs
pulm, hemolytic anemia
non-IgE-mediated
rash
baby heroin
seroquel
bactrim ADEs
sulfa allergy, hyperkalemia, rash, renal failure
gram-negative w/ risk for pseudomonas
zosyn
antistaphylococcal ADE
AAIN
atomoxetine metabolism
CYP
bactrim metabolism
CYP
clarithromycin/erythromycin metabolism
CYP (potent)
acamprosate contraindication
CrCl < 30
ceftaroline
MRSA
daptomycin NOT a good choice for
MRSA pneumonia
misuse of PO vanco can lead to
VRE
stimulants BBW
abuse potential, CV events
metronidazole DIs
alcohol, warfarin
PAE
aminoglycosides
narrow therapeutic window
aminoglycosides
poor tissue distribution
aminoglycosides
FQ DIs
antiarrhythmics, cation chelation
aminoglycosides have a synergistic effect w/
beta lactams and glycopeptides
direct observation not needed for
buprenorphine
poor man's cocaine
bupropion
seizure risk is a class effect
carbapenems
tetracyclines DIs
cation chelation
what can be used for sx associated with opioid withdrawal
clonidine
stimulants increase
dopamine and NE
pts w/ true beta lactam allergy
monobactam
avoid what alcohol use med in hepatic failure
naltrexone
REMS program
naltrexone IM
mu opioid receptor antagonists
naltrexone, naloxone
FQ ADEs
neurotoxicity, QT prolongation, tendon rupture
CAMs for ADHD
omega 3 and 6, ferrous sulfate
good 1st line for children w/ tic d/o
vyvanse
DIs w/ oritavancin
warfarin
bactrim DIs
warfarin
transdermal patch timing
wear up to 9 hrs, effects last 3 hrs after removed
