Immuno Week 7 Quiz

Type ___ hypersensitivity's involve soluble antigen with IgM or IgG forming complexes that can deposit in tissues. 1 2 3 4

3

Hypersensitivity reactions to penicillin have been identified that correspond to which of the below types of reactions? a. Type IV hypersensitivity b. All of the answers are correct. c. Type II hypersensitivity d. Type I hypersensitivity e. Type III hypersensitivity

All of the answers are correct.

Which of the following is NOT an explanation for ineffecient clearing of antibody-antigen complexes that could lead to type III hypersensitivity reactions? a. Compromised phagocytic system b. High affinity for tissues of particular antigens c. Highly charged antigens d.All of the answers could explain inefficient clearing of antibody-antigen complexes. e.Antigens that are prone to formation of lattices when bound by antibodies

All of the answers could explain inefficient clearing of antibody antigen complexes

Which of the following cell types are targets of products of mast-cell degranulations, as well as mediators produced by mast cells following degranulation ? A.) hematopoietic cells b.) nervous tissue c.) epithelial cells d.) smooth muscle e.) all of the answers are correct

All of these answers are correct

Which of the following is NOT involved in the development of type II diabetes ? a. Antibodies against pancreatic islet cells. b.None of the answers are involved in the development of Type II diabetes. c. Signaling from IL-6R. d.Inactivation of components involved in signaling from the insulin receptor by JNK. e. All of the answers are involved in the development of Type II diabetes.

Antibodies against pancreatic islet cells

Which of the following cell types is NOT typically associated with type IV hypersensitivity reactions? a. TH17 b. B cells c. Langerhans cells d.None of the answers are typically associated with type IV hypersensitivity reactions. e. TH1

B cells

Which of the following cell types is NOT typically associated with type IV hypersensitivity reactions? a.None of the answers are typically associated with type IV hypersensitivity reactions. b. Langerhans cells c. TH17 d. TH1 e. B cells

B cells

The potential for hemolytic disease of newborn occurs when a.) maternal Rh− cells enter an Rh+ fetus. b.) fetal Rh+ cells enter an Rh− mother. c.) fetal Rh+ cells enter an Rh+ mother. d.) maternal Rh+ cells enter an Rh− fetus. e.) fetal Rh− cells enter an Rh+ mother.

B.) fetal Rh+ cells enter an Rh- mother

What type of cell would be most instructive in classifying the type of reaction responsible for skin rash? a. CD8+ T cells b. CD4+ T cells c. APCs d. Mast cells e. NK cells

CD4+ cells

The transfusion reaction involves which of the following antigens that are structurally similar to antigens on the surface of commensal bacteria? a. None of the answers are correct. b. Carbohydrates on the surface of erythrocytes c. Fc receptors on the surface of cytotoxic cells d. Fc receptors on the surface of mast cells e. Complement receptors on the surface of APCs

Carbohydrates on the surface of erythrocytes

Which of the following is NOT a possible symptom of a type I hypersensitivity ? Rashes Sneezing Diarrhea Contact dermatitis Rhinitis

Contact dermatitis

The effects of histamine in allergic reactions are primarily attributable to its binding which of the following histamine receptors? a. H2 b. H4 c. None of the answers are correct. d. H3 e. H1

H1

The effects of histamine in allergic reactions are primarily attributable to its binding which of the following histamine receptors? a. H4 b. H1 c. None of the answers are correct. d. H3 e. H2

H1

Which of the following cytokines is NOT generally found in increased concentrations in increased concentrations in individuals with chronic inflammation ? a. IL-1 b. TNF- c. IL-10 d.All of the answers are generally elevated in chronic inflammation. e. IL-6

IL-10

All o the following are involved in type 2 hypersensitivity except: IgM. complement. IgE. foreign cells. IgG.

IgE

All of the following are involved in the development of type 4 hypersensitivity reaction except: TH cells. cytokines. TC cells. macrophages. dendritic cells. antigen. IgE.

IgE

All of the following are involved in type 2 hypersensitivity except, IgE. complement. foreign cells. IgG. IgM

IgE

All of the following are involved in type 2 hypersensitivity, except: IgG. complement. foreign cells. IgE. IgM.

IgE

All of the following are involved in type 2 hypersensitivity, except: foreign cells. IgE. IgG. IgM. complement.

IgE

Type I hypersensitivity is caused by the release of vasoactive products from mast cells coated with: IgM. IgE. IgG. IgA.

IgE

Which immunoglobulin class/es can fix complement ? IgM only IgD only IgE and IgA IgG only IgM and IgG

IgM and IgG

Human blood types involve all of the following except: ABO antigen markers. genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors. genetically determined glycoprotein markers. MHC genes. inheritance of two of three possible alleles.

MHC genes

Human blood types involve all of the following, except: MHC genes. ABO antigen markers. genetically determined glycoprotein markers. genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors. inheritance of two of three possible alleles.

MHC genes

Which of the following is present during both acute and chronic inflammation? a. Macrophages b. Lymphocytes c. Neutrophils d. Monocytes e. Fibroblasts

Neutrophils

A normal individual should only produce IgE in response to which of the following types of antigens? a. Parasite antigens b. Antigens from extracellular bacterial antigens c. All of the answers are correct. d. Viral antigens e. Antigens from intracellular bacterial antigens

Parasite antigens

Which test is used to measure the IgE present in allergic patients? Weil-Felix reaction Rapid Plasma Reagin (RPR) test RIST ELISA fluorescent antibody tests

RIST

Which of the following cytokines is NOT generally associated with allergic reactions? a. TNF-alpha b. All of the answers are associated with allergic reactions. c. GM-CSF d. IL-4 e. TGF- Beta

TGF-.Beta

Which of the following cytokines is NOT generally associated with allergic reactions? a. IL-4 b. TNF-alpha c. GM-CSF d. TGF-B e. All of the answers are associated with allergic reactions

TGF-B

Which of the following reactions features mast cell degranulation as one of its key features? a. TH17 b. B cells c. Langerhans cells d.None of the answers are typically associated with type IV hypersensitivity reactions. e. TH1

Type I hypersensitivity

Which of the following reactions features mast cell degranulation as one of its key features? a. Type III hypersensitivity b. Type II hypersensitivity c. Type I hypersensitivity d. All of the answers are correct. e. Type IV hypersensitivity

Type I hypersensitivity

Which of the following types of hypersensitivity reactions is associated with IgE? a. All of the answers are correct. b. Type II hypersensitivity c. Type III hypersensitivity d. Type IV hypersensitivity e. Type I hypersensitivity

Type I hypersensitivity

Which of the following types of hypersensitivity reactions is associated with IgE? a. Type II hypersensitivity b. All of the answers are correct. c. Type IV hypersensitivity d. Type I hypersensitivity e. Type III hypersensitivity

Type I hypersensitivity

Which of the following types of hypersensitivity reactions includes the transfusion reaction: a. Type I hypersensitivity b. All of the answers are correct. c. Type II hypersensitivity d. Type IV hypersensitivity e. Type III hypersensitivity

Type II hypersensitivity

Formation of immune complexes between antibodies and soluble antigen is considered to be which type of hypersensitivity reaction: a. Type II hypersensitivity b. All of the answers are correct. c. Type IV hypersensitivity d. Type I hypersensitivity e. Type III hypersensitivity

Type III hypersensitivity

Formation of immune complexes between antibodies and soluble antigens is considered to be which type of hypersensitivy reaction ? a. All of the answers are correct. b. Type II hypersensitivity c. Type III hypersensitivity d. Type IV hypersensitivity e. Type I hypersensitivity

Type III hypersensitivity

Which of the following effects is NOT a result of histamine binding to histamine receptor H1? a. Suppression of mast-cell degranulation. b. All of the answers result from histamine binding H1. c. Increased vascular permeability. d. Intestinal smooth muscle contraction. e. Increased mucous secretion.

a.) suppression of mast-cell degranulation

Hypersensitivity reactions to penicillin have been identified that correspond to which of the below types of reactions? A.) all of the answers are correct b.) Type IV hypersensitivity c.) Type III hypersensitivity d.) Type II hypersensitivity e.) Type I hypersensitivity

all of the answers are correct

An Arthur reaction refers to: a. an inflammatory response 4 to 10 hours after exposure. b. a localized type III reaction. c. All of the answers are correct. d. swelling and localized bleeding after a type I response. e. a response to moldy hay or pigeon feces.

all of the answers are correct.

Desensitized therapy works by: A.) producing IgG antibodies to acting ITIMs on other Fc receptors b.) producing IgG antibodies that complete for antigen binding sites with IgE. c.) Inducing anergy of TH2 cells. d.) Switching the response from TH2 to TH1 e.) All of the answers are correct

all of the answers are correct.

Which of the following are proteins that interact directly with antigens during the adaptive immune response? a.) Major histocompatibility complex b.) immunoglobulins c.) T cell receptors d.) all of these

all of these

Desensitization therapy works by a.producing IgG antibodies to activing ITIMs on other Fc receptors. b. inducing anergy of TH2 cells. c. All of the answers are correct. d. switching the response from TH2 to TH1. e.producing IgG antibodies that compete for antigen binding sites with IgE.

all of these are correct

Transfusion of the wrong blood type can cause a.) fever and anemia b.) massive hemolysis of the donor RBCs c.) recipient antibody activating the complement cascade to attack the RBCs/ d.) Systemic shock and kidney failure e.) all of these

all of these choices are correct

The life threatening condition that may develop during a type I hypersensitivity reaction is called septic shock. stroke. toxic shock. anaphylaxis.

anaphylaxis

The serum of a person with blood type A, Rh- will have which f the following antibodies; anti-A, anti-Rh anti-A, anti-B, anti-Rh anti-B, anti-Rh anti-A anti-B

anti-B

Chemokines are a group of small proteins that: a.) potentiate specific immune responses. b.) function as chemoattractants for phagocytes and lymphocytes. c.) attract T cells to sites of injury. d.) attract T cells, phagocytes, and lymphocytes, as well as potentiate specific immune responses.

attract T cells, phagocytes and lymphocytes as well as potentiate specific immune responses

Chemokines are a group of small proteins that: a.) potentiate specific immune responses. b.) function as chemoattractants for phagocytes and lymphocytes. c.) attract T cells to sites of injury. d.) attract T cells, phagocytes, and lymphocytes, as well as potentiate specific immune responses.

attract T cells, phagocytes, and lymphocytes as well as potentiate specific immune responses

The immune response to a peanut allergy is most similar to a: a. None of the answers are similar. b. positive PPD test. c. bee sting. d. transfusion reaction. e. poison ivy rash.

bee sting

What will be the immediate action of allergen when it enters the body for a second time? a.) binding of IgE by the Fc region to mast cells and basophils b.) bonding of allergen to adjacent IgE binding sites on mast cells and basophils c.) degranulation d.) Prostaglandins cause vasodilation and increased vascular permeability. e.) Histamine acts on smooth muscle.

bonding of allergen to adjacent IgE binding sites on mast cells and basophils

What will the immediate action of allergen when it enters the body for the second time?

bonding of allergen to adjacent IgE binding sites on mast cells and basophils

Whta will be the immediate action of allergen when it enters the body for a second time? a.) Histamine acts on smooth muscle. degranulation b.) bonding of allergen to adjacent IgE binding sites on mast cells and basophils c.) Prostaglandins cause vasodilation and increased vascular permeability. d.) binding of IgE by the Fc region to mast cells and basophils

bonding of allergen to adjacent IgE binding sites on mast cells and basophils

Allergic responses may have evolved to: a. protect us from spoiled food. b. break down venom from reptiles. c. All of the answers are correct. d. keep us away from excess pollen. e. prevent blood transfusions.

break down venom from reptiles

Which of the following is most directly responsible for cell lysis in type 2 hypersensitivity reactions ? IgM antibodies IgG antibodies IgE antibodies NK cells TC cells complement activation

complement activation

Which of the following is not a possible symptom of type I hypersensitivity: Rhinitis Sneezing Diarrhea Contact dermatitis Rashes

contact dermatitis

Communication between cells of the immune system is accomplished in many cases through clonal deletion. allelic exclusion. cytokines. allelic exclusion, clonal deletion, and cytokines.

cytokines

Which event releases the chemical mediators: a.) Prostaglandins cause vasodilation and increased vascular permeability. b.) degranulation c.) binding of IgE by the Fc region to mast cells and basophils d.) Histamine acts on smooth muscle. e.) binding of allergen to adjacent IgE binding sites on mast cells and basophils

degranulation

Allergic patients receiving small, controlled injections of specific allergens are undergoing: tissue matching. desensitization. sensitization. degranulation.

desensitization

T/F: A person who is Rh negative will have anti-Rh antibodies in their serum from early infancy

false

T/F: A person who is Rh negative will have anti-Rh antibodies in their serum from early infancy.

false

T/F: Allergy testing which is accomplished by injecting tiny amounts of allergen into the skin and examining the injection site for a reaction is an example of an in vitro test

false

T/F: Allergy testing, which is accomplished by injecting tiny amounts of allergen into the skin and examining the injection site for a reaction is an example of an in vitro test.

false

The potential for hemolytic disease of the newborn occurs when: maternal Rh− cells enter an Rh+ fetus. fetal Rh− cells enter an Rh+ mother. fetal Rh+ cells enter an Rh+ mother. fetal Rh+ cells enter an Rh− mother. maternal Rh+ cells enter an Rh− fetus.

fetal Rh+ cells enter an Rh- mother

Which is mismatched? transfusion reaction - Type 2 hypersensitivity hay fever - Type 4 hypersensitivity food allergy - Type 1 hypersensitivity serum sickness - Type 3 hypersensitivity poison ivy dermatitis - Type 4 hypersensitivity

hay fever- type 4 hypersensitivity

What are the primary chemical mediators released from mast cells during a type I hypersensitivity reaction ? cytokines histamine and serotonin antibodies interleukin I and tumor necrosis factor

histamine and serotonin

Histamine causes all of the following except: a.) relaxes vascular smooth muscle. b.)increased sensitivity to light. c.)constriction of smooth muscle of bronchi and the intestine. d.) wheal and flare reaction in skin. e.) pruritis and headache.

increased sensitivity to light

Which of the following is mismatched? ingestant - nuts ingestant - food additive contactant - rubber injectant - vaccine inhalant - bee sting

inhalant- bee sting

A female who is Rh+ : a.) is at risk for a pregnancy resulting in hemolytic disease of the newborn. b.) inherited two recessive genes. c.) is in the majority of the population with regard to Rh status. d.) can only have an Rh positive baby. e.) All of these choices are correct.

is in the majority of the population with regard to Rh status

A female who is Rh+ is at risk for a pregnancy resulting in hemolytic disease of the newborn. inherited two recessive genes. is in the majority of the population with regard to Rh status. can only have an Rh positive baby. All of these choices are correct.

is in the majority of the population with regard to Rh status.

A person with O type blood: a.) could not have the Rh factor. b.) lacks A and B antigens. c.) is called a universal recipient. d.) lacks antibodies to A and B blood types. e.) All of these choices are correct

lacks A and B antigens

A person with O type blood: could not have the Rh factor. lacks A and B antigens. is called a universal recipient. lacks antibodies to A and B blood types. All of these choices are correct.

lacks A and B antigens

The chemical mediator that causes prolonged brochospasm, vascular permeability and mucus secretion of asthmatic patient is: serotonin. platelet-activating factor. histamine. leukotriene. prostaglandin.

leukotriene

The chemical mediator that causes prolonged bronchospasm, vascular permeability and mucus secretion of asthmatic patients is: platelet-activating factor. histamine. leukotriene. serotonin. prostaglandin.

leukotriene

Which cells play the greatest role in allergic symptoms ? monocytes plasma cells T-cells mast cells eosinophils

mast cells

Which cells play the greatest role in allergic systems: T-cells eosinophils plasma cells mast cells monocyte

mast cells

Which of the following cell types are implicated in type I hypersensitivity reactions? a. None of the answers are correct. b. Neutrophils c. Monocytes d. T cells e. Mast cells and basophils

mast cells and basophils

Which of the following is present during both acute and chronic inflammation ? a. Fibroblasts b. Lymphocytes c. Monocytes d. Neutrophils e. Macrophages

neutrophils

Which of the following is present during both acute and chronic inflammation ? a. Monocytes b. Macrophages c. Lymphocytes d. Neutrophils e. Fibroblasts

neutrophils

Which of the following is present during both acute and chronic inflammation? a. Neutrophils b. Monocytes c. Lymphocytes d. Macrophages e. Fibroblasts

neutrophils

A normal individual should only produce IgE in response to which of the following types of antigens? a. Antigens from intracellular bacterial antigens b. Antigens from extracellular bacterial antigens c. Viral antigens d. Parasite antigens e. All of the answers are correct.

parasite antigens

All of the following cells participate in immune surveillance, except: plasma cells. natural killer cells. macrophages. cytotoxic T-cells. All of the choices participate.

plasma cells

Which of the following is NOT packaged within basophil and mast cell granules? a. All of the answers are found in granules. b. Tryptase c. Heparin d. Prostaglandins e. Histamine

prostaglandins

Epinephrine a.) inhibits the activity of lymphocytes. b.) reverses constriction of airways. c.) is an antihistamine. d.) causes desensitization. e.) All of these choices are correct.

reserves constriction of airways

Epinephrine: inhibits the activity of lymphocytes. reverses constriction of airways. is an antihistamine. causes desensitization. All of these choices are correct

reverses the constriction of airways

The initial encounter with an allergen is called the: sensitizing dose. allergic dose. provocative dose. hypersensitivity dose. desensitizing dose.

sensitizing dose

Large quanitities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes that deposit. in basement membranes occur in; hemolytic disease of the newborn. serum sickness. delayed hypersensitivity. anaphylaxis. All of these choices are correct.

serum sickness

Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes that deposit in basement membranes occur in: hemolytic disease of the newborn. serum sickness. delayed hypersensitivity. anaphylaxis. All of these choices are correct.

serum sickness

All of the following are associated with IgE- and mast cell mediated allergy, except: allergic asthma. systemic lupus erythematosus. anaphylaxis. eczema. drug allergy.

systemic lupus erythematosus

All of the following are associated with IgE- and mast cell-mediated allergy, except: anaphylaxis. allergic asthma. systemic lupus erythematosus. drug allergy. eczema

systemic lupus erythematosus

All of the following are associated with IgE- and mast cell-mediated allergy, except: drug allergy. allergic asthma. systemic lupus erythematosus. eczema. anaphylaxis.

systemic lupus erythematosus

Which of the following is incorrect about the role of mast cells and basophils in allergies: Their cytoplasmic secretory vesicles contain physiologically active cytokines. They degranulate when triggered by a specific allergen through the IgE bound to them. They carry high numbers of cell receptors that bind to IgE antibodies. They are found mainly in the lymph nodes.

they are found mainly in the lymph nodes

Which of the following is incorrect about the role of mast cells and basophils in allergies: a.) They degranulate when triggered by a specific allergen through the IgE bound to them. b.) They carry high numbers of cell receptors that bind to IgE antibodies. c.) Their cytoplasmic secretory vesicles contain physiologically active cytokines. d.) They are found mainly in the lymph nodes.

they are found mainly in the lymph nodes.

T/F: The tuberculin test is an example of an in vivo serological test

true

The tuberculin test is an example of an in vivo serological test

true

Autoantibodies cause tissue injury in all of the following diseases, except: myasthenia gravis. rheumatoid arthritis. multiple sclerosis. tuberculin reaction. Graves' disease.

tuberculin reaction

Autoantibodies cause tissue injury in all of the following diseases, except: tuberculin reaction. rheumatoid arthritis. Graves' disease. multiple sclerosis. myasthenia gravis.

tuberculin reaction

Antibodies consist of four polypeptides. ____ heavy chains, and ___ light chains two / two three / one one / three four / four

two/two

Atrophy and anaphylaxis are hypersensitivities in the category: Type 1 only. Type 1, Type 2, Type 3. Type 4 only. Type 1 and Type 4. Type 1, Type 2, Type 3, and Type 4.

type 1 only

The major categories of hypersensitivity's that typically involve B-cell immunoglobulin response is/are:; Type 1 and Type 4. Type 1, Type 2, Type 3, and Type 4. Type 1 only. Type 1, Type 2, Type 3. Type 4 only.

type 1,2 and 3

The Arthus reaction is considered to be which of the following hypersensitivity types? a. Type IV hypersensitivity b. All of the answers are correct. c. Type I hypersensitivity d. Type II hypersensitivity e. Type III hypersensitivity

type III hypersensitivity