Insulin Onset, Peak, Duration, Action

Rapid-acting ONSET

15min

Long-acting ONSET

1h

Short-acting PEAK

2-5h

Long-acting DURATION

20-26h

Rapid-acting DURATION

3-5h

Short-acting ONSET

30-60min

Rapid-acting PEAK

30-90min

Short-acting DURATION

5-8h

Insulin glargine/Lantus

Onset 1 hr Peak NONE Duration 20-26h Long acting

50% insulin lispro protamine & 50% insulin lispro/Humalog Mix 50/50

Onset 10-15m Peak Varies Duration 10-16h Mixed intermediate & rapid

75% insulin lispro protamine & 25% insulin lispro/Humalog Mix 75/25

Onset 10-15m Peak Varies Duration 10-16h Mixed intermediate & rapid

Insulin aspart/NovoLog

Onset 15m Peak 30-90m Duration 3-5h Rapid acting

Insulin glulisine/Apidra

Onset 15m Peak 30-90m Duration 3-5h Rapid acting

Insulin lispro/Humalog

Onset 15m Peak 30-90m Duration 3-5h Rapid acting

Insulin detemir/Levemir

Onset 1h Peak NONE Duration 20-26h Long acting

Regular insulin/Humulin R/Novolin R

Onset 30-60m Peak 2-5h Duration 5-8h Short-acting

50% NPH & 50% regular/Humulin 50/50

Onset 30-60m Peak Varies Duration 10-16h Mixed intermediate & short

70% NPH & 30% regular/Humulin 70/30

Onset 30-60m Peak Varies Duration 10-16h Mixed intermediate & short

70% insulin aspart protamine & 30% insulin aspart/NovoLog Mix 70/30

Onset 5-15m Peak Varies Duration 10-16h Mixed intermediate & rapid

Long-acting PEAK

none