Insulin Onset, Peak, Duration, Action
Rapid-acting ONSET
15min
Long-acting ONSET
1h
Short-acting PEAK
2-5h
Long-acting DURATION
20-26h
Rapid-acting DURATION
3-5h
Short-acting ONSET
30-60min
Rapid-acting PEAK
30-90min
Short-acting DURATION
5-8h
Insulin glargine/Lantus
Onset 1 hr Peak NONE Duration 20-26h Long acting
50% insulin lispro protamine & 50% insulin lispro/Humalog Mix 50/50
Onset 10-15m Peak Varies Duration 10-16h Mixed intermediate & rapid
75% insulin lispro protamine & 25% insulin lispro/Humalog Mix 75/25
Onset 10-15m Peak Varies Duration 10-16h Mixed intermediate & rapid
Insulin aspart/NovoLog
Onset 15m Peak 30-90m Duration 3-5h Rapid acting
Insulin glulisine/Apidra
Onset 15m Peak 30-90m Duration 3-5h Rapid acting
Insulin lispro/Humalog
Onset 15m Peak 30-90m Duration 3-5h Rapid acting
Insulin detemir/Levemir
Onset 1h Peak NONE Duration 20-26h Long acting
Regular insulin/Humulin R/Novolin R
Onset 30-60m Peak 2-5h Duration 5-8h Short-acting
50% NPH & 50% regular/Humulin 50/50
Onset 30-60m Peak Varies Duration 10-16h Mixed intermediate & short
70% NPH & 30% regular/Humulin 70/30
Onset 30-60m Peak Varies Duration 10-16h Mixed intermediate & short
70% insulin aspart protamine & 30% insulin aspart/NovoLog Mix 70/30
Onset 5-15m Peak Varies Duration 10-16h Mixed intermediate & rapid
Long-acting PEAK
none