Pharm I EAQ Ch. 47
A patient is diagnosed with non-Hodgkin's lymphoma. The patient developed fever and chills after the administration of rituximab. Which treatments should the nurse include as premedication to prevent allergy in the patient?
- Acetaminophen - Diphenhydramine
A patient is administered aldesleukin for the treatment of non-Hodgkin's lymphoma. After 4 months, which diagnostic results confirm that the patient's has recovered?
- Healthy skin - No signs of infection - Normal nutritional status
If the patient with a dust allergy has 4000 T helper cells, how many T suppressor cells does the patient have?
2000
A patient has been prescribed monoclonal antibody therapy for rheumatoid arthritis. Which disorder or disease is a contraindication and would alert the nurse to question the order for this class of drugs?
AIDS
Which patient lab report would alert the nurse to request that the primary HCP discontinue filgrastim therapy?
Absolute neutrophil count above 10,000 cells/mm3
A patient had been treated with myelosuppressive antineoplastic drugs during bone marrow transplantation. The nurse finds that the white blood cell (WBC) count of the patient has dropped to a critical level. Which reason explains the patient's condition?
Administration of filgrastim less than 24 hours prior to chemotherapy
Which symptom is an expected adverse effect of hematopoietic drugs?
Alopecia
Which biologic or chemical substance is recognized as foreign by the body's immune system?
Antigen
Which cells are the functional cells of the humoral immune system that mature into immunoglobins?
B Cells
A patient is receiving lithium therapy for bipolar disorder. Which result in the patient is expected if filgrastim is administered for neutropenia?
Bone marrow stimulation
The nurse would teach patients receiving filgrastim to expect which side effect?
Bone pain
Which point about filgrastim would the nurse keep in mind before beginning myelosuppressive antineoplastic drug therapy in a patient with cancer?
Can be initiated 24 hours prior to chemotherapy.
Which medication would the nurse expect the primary health care provider to prescribe for a patient with metastatic colorectal cancer who is on irinotecan therapy and develops an allergic reaction?
Cetuximab
A patient was administered aldesleukin for metastatic renal cell carcinoma. The patient's blood pressure is now dropping rapidly. Which cause of falling blood pressure does the nurse suspect?
Concurrent antihypertensive drugs
Which antitumor necrosis factor is used in the treatment of ankylosing spondylitis?
IInfliximab
Which drug would the nurse administer to relieve severe bone pain in a patient administered methotrexate for rheumatoid arthritis?
Ibuprofen
A patient is affected by a dust allergy. Which antibodies are elevated in the patient?
IgE antibodies
A patient who has no known exposure to tuberculosis is administered etanercept for the treatment of severe chronic plaque psoriasis. Which is a possible result if cyclophosphamide is administered?
Increased severity of plaque psoriasis
Which drug is prescribed to treat ankylosing spondylitis and carries a US FOOD & Drug Administration (FDA) black box warning for patients with heart failure or latent tuberculosis?
Infliximab
Which immunomodulating drugs are contraindicated in the treatment of multiple sclerosis in a patient with an allergy to human albumin?
Interferon beta-1a
Which prescribing guideline for methotrexate would the nurse keep in mind before administering the drug to a patient for rheumatoid arthritis?
It is given once per week and not once per day
Which drug would have a reduced clearance with concurrent administration of interferon beta-1a, used in the treatment of multiple sclerosis?
Natalizumab
Which monoclonal antibody drug is prescribed to patients with multiple sclerosis?
Natalizumab
A patient with a low platelet count is prescribed a drug to stimulate platelet production. Which drug would the nurse anticipate being prescribed?
Oprelvekin
After administering etanercept subcutaneously for chronic plaque psoriasis, the nurse learns that the patient has a history of tuberculosis. Which consequence would the nurse anticipate in the patient?
Reactivation of tuberculosis
The nurse is instructed to premedicate the patient with severe rheumatoid arthritis before administering tocilizumab intravenously. Which adverse effect of tocilizumab is the reason for this instruction?
Risk of allergy including anaphylaxis
The nurse suspects that the patient has developed bone marrow suppression after administration of methotrexate for rheumatoid arthritis. Which symptom confirm bone marrow suppression in the patient?
Severe bone pain
Which adverse effect is associated with filgrastim?
Severe bone pain
Which cells are activated by aldersleukin (interleukin-2)?
T Cells
A patient has erythema nodosum due to the use of oral contraceptives. Which immunostimulant drug is used to treat erythema nodosum?
Thalidomide
Which monoclonal antibody is used in the treatment of breast cancer?
Trastuzumab
The nurse is caring for a patient with cancer who is receiving bevacizumab. Which monitoring tests would the nurse perform for this patient?
White blood cell count