What causes muscle fatigue?

Glycogen depletion has been found to be selective to what muscle groups?

Selective to muscle groups involved in the activity. Pattern of glycogen depletion from Type I and II fibers depends on the duration and intensity of the activity.

For a muscular contraction to occur, what do you need?

-Acetylcholine to bind at the neuromuscular junction -Calcium dependent binding -ATP Dependent release

What are the possible causes for central fatigue?

-interruptions in motor coordination in the motor cortex. -interference in motor control circuits in the basal ganglia. -inhibition of voluntary effort. -psychological factors such as motivation and perceived competence. -pain perception and tolerance. -neural malfunctions *central fatigue is the main reason we stop exercising in the middle of it.

What are the two categories that mechanisms of this process fall into?

1) Running out of fuel: depletion of neurotransmitters and energy sources. 2) Buildup: accumulation of metabolic byproducts.

What is the pH level where muscles operate best?

6.9 and 7.1

What does peripheral fatigue cause?

It causes contractile dysfunction that is manifested in the eventual reduction or lack of ability of a single muscle or local group of muscles to do work.

What is peripheral fatigue?

It is considered an inability for the body to supply sufficient energy or other metabolites to the contraction muscles to meet the increased energy demand.

How does fatigue occur?

It results in the cessation of muscular work or the inability to maintain a given intensity of work.

What happens when the pH falls lower than 6.9?

The cellular processes of energy production and muscle contraction begin to slow.

What happens when pH reaches 6.4?

The myosin can no longer bind to actin and muscle contraction stop.s