Adipose Tissue

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Adipocytes function

Energy storage, insulation, space filled as cushion

Major adipokines secreted by WAT

PGI2, PGF2 alpha, leptin, adiponectin, resistin, visfatin, apelin, angiotensinogen, AGA 2, Interlukins, bone morphogenic protien, fatty acids and estrogen

Master switch of regulation of WAT differentation

PPARy/ RXR

Master switch for BAT differention

PRDM/PGC-1

Two types of adipose tissue

White and brown adipose tissue

Adipose tissue

a specialized connective tissue that plays an important role in energy homeostasis and hormone production

Adipose tissue is an important part in?

energy homeostasis, adipogenesis, steroid metabolism, angiogenesis and immune response

White adipose tissue functions

energy storage, insulation, cushion for vital organs and secretion of hormones

Adipocytes

fat filled cells, ring shaped cells filled with triglycerides chicken wire appearance nucleus is pressed against cell membrane

Adipokines

hormone production

Brown Adipose tissue

multilocular

Brown adipose tissue

present in newborns mitochondira of brown fat cells express uncoupling protein which short curcuits the ETC producing heat instead of ATP

Subcutaneous fasicia

provides a significant thermal insulation against cold by reducing the rate of heat loss

WAT stucture

spherical but looks oval shaped when a lot supplied with blood vessels and capillaries

Adipocytes location

subcutaneous fat beneath skin, breast, heart surface, surrounds organs, joints, eyeball and is with the abdomen.

White adipose tissue

unilocular


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